1,720,987 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
ACTIVE H1-RECEPTORS PROTECT AGAINST THE HARMFUL EFFECTS OF H2-RECEPTORS IN A HISTAMINE INDUCED BRAIN EDEMA MODEL
No full textActive traumatic brain injury (TBI), high levels of histamine may participate in the pathophysiology of secondary brain injury. Histaminergic neurons project throughout the entire brain and are activate during brain diseases accompanied by edema. Interfering with histamine signaling influences the outcome after neurological insults in animals. We developed a histamine induced brain edema model in rats. Intracerebroventricular (ICV) application of histamine dose dependently impairs survival and water homeostasis in the adult rat brain as documented by increased intracranial pressure (ICP). In this new experimental model, selective histamine agonists and antigonists were tested. We show an acute toxic effect of H2-receptor activity, which disappears when H1-receptors are activated. We conclude that active H1-receptors protect against the toxic H2-effect. This shielding effect of H1-receptor activity is confirmed in several experiments. Therefore the use of central penetrating H1-antagonists must be avoided in patients with a suspected elevated histamine concentration in the brain, for example TBI-patients
ACTIVE H1-RECEPTORS PROTECT AGAINST THE HARMFUL EFFECTS OF H2-RECEPTORS IN A HISTAMINE INDUCED BRAIN EDEMA MODEL
No full textActive traumatic brain injury (TBI), high levels of histamine may participate in the pathophysiology of secondary brain injury. Histaminergic neurons project throughout the entire brain and are activate during brain diseases accompanied by edema. Interfering with histamine signaling influences the outcome after neurological insults in animals. We developed a histamine induced brain edema model in rats. Intracerebroventricular (ICV) application of histamine dose dependently impairs survival and water homeostasis in the adult rat brain as documented by increased intracranial pressure (ICP). In this new experimental model, selective histamine agonists and antigonists were tested. We show an acute toxic effect of H2-receptor activity, which disappears when H1-receptors are activated. We conclude that active H1-receptors protect against the toxic H2-effect. This shielding effect of H1-receptor activity is confirmed in several experiments. Therefore the use of central penetrating H1-antagonists must be avoided in patients with a suspected elevated histamine concentration in the brain, for example TBI-patients
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
The Fabry disease-associated lipid Lyso-Gb3 enhances voltage-gated calcium currents in sensory neurons and causes pain
No full textFabry disease is an X-linked lysosomal storage disorder characterised by accumulation of glycosphingolipids, and accompanied by clinical manifestations, such as cardiac disorders, renal failure, pain and peripheral neuropathy. Globotriaosylsphingosine (lyso-Gb3), a deacylated form of globotriaosylceramide (Gb3), has emerged as a marker of Fabry disease. We investigated the link between Gb3, lyso-Gb3 and pain. Plantar administration of lyso-Gb3 or Gb3 caused mechanical allodynia in healthy mice. In vitro application of 100nM lyso-Gb3 caused uptake of extracellular calcium in 10% of sensory neurons expressing nociceptor markers, rising to 40% of neurons at 1μM, a concentration that may occur in Fabry disease patients. Peak current densities of voltage-dependent Ca(2+) channels were substantially enhanced by application of 1μM lyso-Gb3. These studies suggest a direct role for lyso-Gb3 in the sensitisation of peripheral nociceptive neurons that may provide an opportunity for therapeutic intervention in the treatment of Fabry disease-associated pain
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