45,981 research outputs found
Semantic Web Meets Autonomic Ubicomp
No full textThe placement of autonomic systems’ management functionality into a ubiquitous computing environment is a difficult task due to the lack of systems’ resources and the need for ‘intelligence’ to ensure that the system is selfhealing/ organising or configuring. For such systems to adapt to changes to their current environment they need to be able to (re) configure the workflow of their services. In this paper, we propose the ANS, an autonomic middleware for ubicomp devices. We briefly describe the architecture of ANS and its autonomic behaviour. The ANS follows a service centric design and therefore lends itself to semantic service description. This paper introduces the concept of services with ancillary behaviour and illustrates the use of OWL-S to semantically describe them. Commitment is discussed as an example of ancillary behaviour which can be used to achieve self-healing at service level. We illustrate our approach with examples from the homecare scenario of a cardiac patient
Nesting Behavior of Red-throated Caracaras
No full text<p>Nest camera videos and pictures from Red-throated Caracara nests at the Nouragues station, French Guiana from 2008 and 2009. For more, see this paper: McCann, S., Moeri, O., Jones, T., O'Donnell, S., & Gries, G. (2010). Nesting and nest-provisioning of the Red-throated Caracara (Ibycter americanus) in central French Guiana. Journal of Raptor Research, 44(3), 236-240. http://dx.doi.org/10.3356/JRR-09-75.1</p
P Values and Statistical Significance
No full textThis resource, created by author Will G. Hopkins, defines what a p-value is, why .05 is significant, and when to use it. It also covers related topics such as one-tailed/two-tailed tests and hypothesis testing. Overall, this is a wonderful resource for students wanting to learn more about statistics, and more specially, significant testing
Professor Anthony H. Gershlick
No full textInterventional cardiology has lost one of its most prominent leaders, trainers, and researchers in Professor Tony Gershlick who died from COVID-19 on 20th November 2020 at the hospital he had worked in for over 30 year
L-optimal transportation for Ricci flow
No full textWe introduce the notion of L-optimal transportation, and use it to construct a natural monotonic quantity for Ricci flow which includes a selection of other monotonicity results, including some key discoveries of Perelman [13] (both related to entropy and to L-length) and a recent result of McCann and the author [11]
Sub-Series 2: Community Participants
No full textOfficial mortgage documents notarized by Robert G. Pugh for Warren G. H. King and Resia Mary McCann King. Witnesses to attest this event were Faye Forshee and Eulalie P. Brown
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Universal neonatal hearing screening moving from evidence to practice
No full textRecent technological advances have made feasible universal newborn hearing screening and therefore early detection of permanent childhood hearing impairment. Over the past three years, new information has been published on whether early intervention is beneficial, the possibility of harm arising from newborn screening, and its cost. Dramatic progress has been made in the large scale implementation of universal screening in many parts of the western world
sj-docx-1-jic-10.1177_08850666231198030 - Supplemental material for The Association of Nonmodifiable Patient Factors on Antipsychotic Medication use in the Intensive Care Unit
No full textSupplemental material, sj-docx-1-jic-10.1177_08850666231198030 for The Association of Nonmodifiable Patient Factors on Antipsychotic Medication use
in the Intensive Care Unit by Jennifer Connell, Brittany McCann, Xiaoke Feng, Matthew S. Shotwell, Christopher G. Hughes and Christina S. Boncyk in Journal of Intensive Care Medicine</p
Transcriptional subtyping and CD8 immunohistochemistry identifies patients with stage II and III colorectal cancer with poor prognosis who benefit from adjuvant chemotherapy
No full textPurpose Transcriptomic profiling of colorectal cancer (CRC) has led to the identification of four consensus molecular subtypes (CMS1 to 4) that have prognostic value in stage II and III disease. More recently, the Colorectal Cancer Intrinsic Subtypes (CRIS) classification system has helped to define the biology specific to the epithelial component of colorectal tumors; however, the clinical value of these classification systems in the prediction of response to standard-of-care adjuvant chemotherapy remains unknown. Patients and Methods Using samples from four European sites, we assembled a novel cohort of patients with stage II and III CRC (n = 156 samples) and performed transcriptomic profiling and targeted sequencing and generated a tissue microarray to enable integrated multiomics analyses. We also accessed data from two published cohorts of patients with stage II and III CRC: GSE39582 and GSE14333 (n = 479 and n = 185 samples, respectively). Results The epithelial-rich CMS2 subtype of CRC benefitted significantly from treatment with adjuvant chemotherapy in both stage II and III disease (P = .02 and P < .001, respectively), whereas the CMS3 subtype significantly benefitted in stage III only (P = .001). After CRIS substratification of CMS2, we observed that only the CRIS-C subtype significantly benefitted from treatment with adjuvant chemotherapy in stage II and III disease (P = .0081 and P < .001, respectively), whereas the CRIS-D subtype significantly benefitted in stage III only (P = .0034). We also observed that CRIS-C patients with low levels of CD8+ tumor-infiltrating lymphocytes were most at risk for relapse in both stage II and III disease (log-rank P = .0031; hazard ratio, 12.18 [95% CI, 1.51 to 98.58]). Conclusion Patient stratification using a combination of transcriptional subtyping and CD8 immunohistochemistry analyses is capable of identifying patients with poor prognostic stage II and III disease who benefit from adjuvant standard-of-care chemotherapy. These findings are particularly relevant for patients with stage II disease, where the overall benefit of adjuvant chemotherapy is marginal
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