479 research outputs found
The virtues of Fukuda laboratory of crystal growth
No full textAbstractThe author, dealing with crystal growth of II–VI, IV–VI and III–V compounds for more than 25 years, describes his impressions on the state of art of the basic research in the field of bulk growth of electronic materials in Japan, obtained during his stay from 1993 to 1994 as invited professor at the laboratory of Professor Tsuguo Fukuda at the Institute for Materials Research of Tohoku University in Sendai. He learned that the future generations of electronic and optical devices require original ideas and unconventional steps towards new bulk crystal growth technologies combined with a close teamwork between academic laboratories and industry
Impact of Fatigue on Quality of Life in People With Parkinson’s Disease
No full textAbstract
Date Presented 3/30/2017
The symptom of fatigue was shown to be an effector for quality of life (QOL) in people with Parkinson’s disease (PD) independently from motor function–related PD symptoms. Intervention to improve specific aspects of fatigue is recommended to promote better QOL for people with PD.
Primary Author and Speaker: Kayoko Takahashi
Contributing Authors: Naoto Kamide, Michinari Fukuda</jats:p
Making it Just in Time: Author-Creator Matsumoto Taiyō
No full textTranslated by Jon Holt and Teppei Fukuda
The first time I can remember encountering Matsumoto Taiyō’s work was probably when he released his short story collection, Blue Spring (Aoi haru - Matsumoto Taiyō tanpenshū [stories published from 1990 to 1993; Shōgakukan, 1993]). All of the stories concern a bunch of young dudes -- full of desires, frustrations, and violent tendencies -- and no chance they can ever get past those things. I thought to myself at that time, “Ah, I bet this stuff means a lot to readers in their teens, but they don’t really do anything for me.” After all, I was a man in my forties, so this stuff wasn’t on my radar as I was busy becoming a grown-up. Keep in mind that Taiyō himself was just in his early twenties. So, it really wasn’t that unnatural for him to write about life like that
複数の癌抑制型マイクロRNAの制御を受けるCoronin1Cは、膵菅腺癌の遊走能、浸潤能を促進する
No full text鹿児島大学博士(医学)Doctor of Philosophy in Medical Science博士論文全文, 博士論文要旨, 最終試験結果の要旨, 論文審査の要旨Coronin proteins are actin-related proteins containing WD repeat domains encoded by seven genes (CORO1A, CORO1B, CORO1C, CORO2A, CORO2B, CORO6, and CORO7) in the human genome. Analysis of large cohort data from The Cancer Genome Atlas revealed that expression of CORO1A, CORO1B, CORO1C, CORO2A, and CORO7 was significantly upregulated in pancreatic ductal adenocarcinoma (PDAC) tissues (p < 0.05). Moreover, high expression of CORO1C and CORO2A significantly predicted the 5 year survival rate of patients with PDAC (p = 0.0071 and p = 0.0389, respectively). In this study, we focused on CORO1C and investigated its functional significance and epigenetic regulation in PDAC cells. Knockdown assays using siRNAs targeting CORO1C were performed in PDAC cells. Aggressive cancer cell phenotypes, especially cancer cell migration and invasion, were inhibited by CORO1C knockdown. The involvement of microRNAs (miRNAs) is a molecular mechanism underlying the aberrant expression of cancer-related genes in cancer cells. Our in silico analysis revealed that five miRNAs (miR-26a-5p, miR-29c-3p, miR-130b-5p, miR-148a-5p, and miR-217) are putative candidate miRNAs regulating CORO1C expression in PDAC cells. Importantly, all five miRNAs exhibited tumor-suppressive functions and four miRNAs except miR-130b-5p negatively regulated CORO1C expression in PDAC cells. CORO1C and its downstream signaling molecules are potential therapeutic targets in PDAC.Kosuke Fukuda, Naohiko Seki, Ryutaro Yasudome, Reiko Mitsueda, Shunichi Asai, Mayuko Kato,Tetsuya Idichi, Hiroshi Kurahara and Takao Ohtsuka
Coronin 1C, Regulated by Multiple microRNAs, Facilitates Cancer Cell Aggressiveness in Pancreatic Ductal Adenocarcinoma
Genes 2023, 14(5), 995
https://doi.org/10.3390/genes14050995doctoral thesi
Paraehlersia martapolae Fukuda, Centurión, Nogueira & Martín, 2012, sp. nov.
No full textParaehlersia martapolae sp. nov. Figures 4–6; Table 3 Material examined. Brazil, State of Rio de Janeiro, offshore: 1 spec. (MZUSP 0 0 978, paratype 3), coll. 2 Mar 1998, 21° 51 ’S 40 °07’W, 110 m; 1 spec. (ZUEC-POL 9696), coll. 2 Mar 1998, 22°02’S 40 °05’W, 93 m; 1 spec. (MZUSP 00979), coll. 28 Feb 1998, 23° 20 ’S 41 ° 22 ’W, 110 m; 1 spec. (ZUEC-POL 9699), coll. 14 Feb 1998, 24° 11 ’S 43 ° 26 ’W, 330 m. State of São Paulo, offshore: 2 specs (MNCN 16.01/ 13610, paratype 4; MZUSP 0 1005, paratype 5), coll. 11 Jan 1998, 24°07’S 44 ° 42 ’W, 101 m; 10 specs (MZUSP 0 0 977, holotype; MZUSP 0 1004, paratype 1; MNCN 16.01/ 13609, paratype 2; ZUEC-POL 9697, paratype 6; MZUSP 00980), coll. 9 Jan 1998, 24°07’S 45 ° 51 ’W, 147 m. State of Paraná, offshore: 1 spec. (ZUEC-POL 9700), coll. 17 Mar 1998, 28º 40 ’S 47 º 25 ’W, 285 m. State of Santa Catarina, offshore: 1 spec. (MZUSP 00981), coll. 22 Mar 1998, 28º 41 ’S 48 º 18 ’W, 104 m; 1 spec. (ZUEC-POL 9698), coll. 22 Mar 1998, 28º 53 ’S 47 º 48 ’W, 225 m. Type series. Data on each specimen of the type series are provided in Table 3. Comparative material examined. Paraehlersia weissmannioides (Augener, 1913). Australia, Western Australia, Shark Bay, Useless Inlet: 1 spec. (ZMH V- 7949, holotype) coll. Michaelsen, 26 °08´S 113 ° 21´E, 7 m. Description. Holotype (MZUSP 00977) largest specimen, complete, with 65 chaetigers, 4.72 mm long, 0.23 mm wide (Table 3); body without colour patterns (Fig. 4 A); peristomium and chaetigers throughout with 1–2 tranverse rows of cilia dorsally extending to near bases of dorsal cirri (Fig. 5 A–B). Palps triangular, longer than prostomium (Figs. 4 A; 5 A–C), occasionally with tips ventrally bent. Prostomium oval, 2 pairs of eyes in open trapezoidal arrangement and 1 pair of anterior eyespots (Fig. 4 A); median antenna inserted between posterior pair of eyes, almost twice as long as prostomium and palps together, with up to 20 articles distally; lateral antennae inserted in front of anterior pair of eyes, similar to median antenna but about two thirds as long, with up to 15 articles distally (Figs. 4 A; 5 A–B). Nuchal organs as 1 pair of dorso-lateral ciliary bands posterior to insertion of median antenna (Fig. 5 A–B). Peristomium dorsally shorter than chaetigers, frequently covering nuchal organs (Fig. 5 A–B); dorsal peristomial cirri about as long as lateral antennae or slightly shorter, sometimes irregularly articulated distally; ventral peristomial cirri about two thirds length of dorsal peristomial cirri, usually smooth (Fig. 4 A). Dorsal cirri with nearly inconspicuous alternation in length along body, longer cirri approximately as long as body width, shorter cirri about two thirds to half length of longer cirri (Fig. 4 A). Antennae, peristomial and dorsal cirri with short cirrophores (Fig. 5 A–D); ovate to digitiform ventral cirri, shorter than parapodial lobes on anterior body (Fig. 5 C), progressively slightly longer, about as long as parapodial lobes from midbody (Fig. 4 A). Anterior parapodia with small, rounded subcirral papilla underneath each dorsal cirrus (Fig. 5 D); parapodial lobes conical (Figs. 4 A; 5 A–B). Anterior parapodia with 2–4 spiniger-like chaetae and 10–15 falcigers each, 1–3 spiniger-like chaetae and 5–7 falcigers on midbody parapodia, 0–1 spiniger-like chaetae and 3–6 falcigers on each posterior parapodium (Table 3). Spiniger-like chaetae with thin shafts, progressively slightly thinner towards posterior body (Figs. 4 B–C; 6 A); elongate, slender blades, bidentate with both teeth minute, subdistal tooth smaller than distal tooth, with short spines on margin (Fig. 4 B–C), 77 – 35 μm long on anterior body, 82 – 37 μm long on midbody, 75 – 22 μm long on posterior body, spiniger-like chaetae absent on last chaetigers (Table 3). Falcigers with subdistally slightly spinulated shafts, tips of shafts with slightly more sigmoid distal beaks towards posterior body; bidentate blades with subdistal tooth smaller than distal one on anterior body (Fig. 4 D), distal tooth progressively slightly smaller and subdistal tooth progressively stouter towards posterior body (Figs. 4 D–F; 6 A–D); blades with short, thin spines on margin (Figs. 4 D–F; 6 A–D); blades 32 – 12 μm long on anterior body, 17 – 7 μm long on midbody, 15 – 8 μm long on posterior body (Table 3). Dorsal simple chaetae present from midbody (Table 3), sigmoid, distally irregularly rounded, with short and coarse subdistal spines (Figs. 4 G; 6 E). Ventral simple chaetae on posterior segments only (Table 3), sigmoid, bidentate with distal tooth smaller than subdistal one, with short subdistal spines (Figs. 4 H; 6 F). Anterior parapodia with up to 2 aciculae each, subdistally bent at almost right angle, sometimes apparently flattened at top (Fig. 4 I); single acicula per parapodium from midbody, similar to anterior ones, but more conspicuously bent (Fig. 4 J). Pygidium with 2 long, thin anal cirri and conical median papilla. Pharynx through 9–12 segments (Table 3), with crown of 13 papillae surrounding its opening and conical central tooth close to anterior margin (Fig. 4 A; 5 B–C); proventricle through 5 –6.5 segments, with 21–24 muscle-cell rows (Fig. 4 A; Table 3). Remarks. Paraehlersia martapolae sp. nov., is characterized by having dorsal simple chaetae distally irregularly rounded, with short and coarse subdistal spines, which does not occur in any other species of Paraehlersia (Table 2). Paraehlersia weissmannioides (Augener, 1913), from Australia, has relatively similar dorsal simple chaetae, but has compound and ventral simple chaetae with subdistal aristae extending beyond the level of subdistal tooth, as well as aciculae of three types: straight, distally rounded and with oblique tip (San Martín & Hutchings 2006), instead of compound and ventral simple chaetae with progressively shorter marginal spines towards tip, without subdistal aristae, and aciculae subdistally bent almost at right angle as in P. martapolae sp. nov. The absence of dorsal simple chaetae in anterior fragments often difficults the identification of Paraehlersia species, and this is particularly true for the distinction between P. longichaetosa sp. nov., and P. martapolae sp. nov. In addition to the morphology of dorsal simple chaetae, P. longichaetosa sp. nov., and P. m a r ta p ol a e sp. nov., differ because the latter has blades of spiniger-like chaetae more distinctly bidentate (Figs. 1 B–D vs. 4 B–C) and blades of anterior body falcigers with subdistal tooth smaller than distal tooth, sometimes resembling an enlarged spine (Fig. 4 D), aciculae apparently flattened at the top (Fig. 4 I–J), and longer pharynx and shorter proventricle. In contrast, P. longichaetosa sp. nov., has blades of anterior body falcigers with both teeth similar (Figs. 1 B; 3 A, C); aciculae distally enlarged, sometimes apparently hollow (Fig. 1 G–I), and a shorter pharynx and longer proventricle (see Tables 1 and 3). Etymology. This species is named after Dr Marta Pola, colleague and friend of the last author in the Universidad Autónoma de Madrid, well known specialist in nudibranchs.Published as part of Fukuda, Marcelo Veronesi, Centurión, Romina, Nogueira, João Miguel De Matos & Martín, Guillermo San, 2012, Two new species of Paraehlersia San Martín, 2003 (Polychaeta, Syllidae) from the Atlantic Coast of South America, pp. 38-52 in Zootaxa 3264 on pages 46-51, DOI: 10.5281/zenodo.28073
Pista nonatoi Nogueira, Harris, Hutchings & Fukuda, 2011, spec. nov.
No full textPista nonatoi spec. nov. Figures 3–6 Pista corrientis. Blankensteyn 1988: 51 –54, Fig. 10; Nogueira 2000: p. 180–183, Figs. 42–43; Alves 2008: 70 –74, Figs. 21 B, 22–23. ? Pista corrientis. Hartman 1966: 97 –99, Figs. 4–9. Material examined. Brazil, State of Rio de Janeiro, offshore: 1 spec., coll. 2 Mar 1998, 21° 51 'S 40 °07'W, 110 m; 23 specs, coll. 14 Feb 1998, 24°02'S 43 ° 30 'W, 147 m. Brazil, State of São Paulo, offshore: 1 spec., coll. 12 Jan 1998, 24° 46 'S 45 ° 11 'W, 99 m; 5 specs, coll. 16 Dec 1997, 25° 11 'S 47 °08'W, 157 m. – Ubatuba, offshore: 8 specs, coll. 17 Mar 2001, 23° 25 'S 44 ° 46 'W, 35 m; 1 spec., coll. 10 Jun 2001, 23° 25 'S 44 ° 46 'W, 35 m; 1 spec., coll. 21 Mar 2002, 23° 31 'S 45 °05'W, 8 m; 1 spec., coll. 23 Mar 2002, 23° 32 'S 45 °05'W, 15.5 m; 1 spec., coll. 23 Mar 2002, 23° 33 'S 45 °04'W, 23.4 m; 1 spec., coll. 20 May 2002, 23° 48 'S 45 ° 10 'W, 30.1 m. Ubatuba, Praia de Picinguaba, 23 ° 22 'S 44 ° 50 'W, in algae: 6 specs, coll. 8 Jun 2001; 1 spec., coll. 8 Oct 2001; 2 specs, coll. 18 Oct 2001. – Caraguatatuba, offshore: 1 spec., coll. 22 Apr 2001, 23° 42 'S 45 ° 11 'W, 25 m; 1 spec., coll. 27 Nov 2002, 23° 43 'S 45 ° 18 'W, 11 m; 1 spec., coll. 15 Feb 2001, 23° 53 'S 45 ° 30 'W, 25 m. Caraguatatuba, Praia de Martim de Sá, 23 ° 37 'S 45 ° 22 'W, in algae: 1 spec., coll. 16 Mar 2001. – São Sebastião, offshore: 2 specs, coll. 13 Feb 2001, 23° 42 'S 45 ° 11 'W, 25.2 m; 1 spec., coll. 27 Jun 2001, 23° 46 'S 45 ° 10 'W, 39.3 m. São Sebastião, Praia de São Francisco, 23 ° 44 'S 45 ° 24 'W, rocky shore, intertidal: 1 spec., coll. 24 Jul 2005. São Sebastião, Praia da Baleia, 23 ° 46 'S 45 ° 39 'W, rocky shore, intertidal: 1 spec., coll. 23 Jul 2005; 1 spec., coll. 17 Oct 2005. Guarujá, Ilha das Palmas, 24 °00'S 46 ° 19 'W, rocky shore, intertidal: 1 spec., coll. 6 Mar 2004; 1 spec., coll. 5 Oct 2005. Brazil, State of Paraná, Paranaguá Bay, 25 ° 33 'S 48 ° 25 'W: 2 specs (MCEM-BPO 282), coll. 27 Feb 1986, Paranaguá Bay. Brazilian southeastern/southern continental shelf: 2 specs (MCEM-BPO 271), coll. 26 Mar 1984, 24° 16 'S 46 °01'02''W, 45 m, sand; 1 spec. (MCEM-BPO 274), coll. 22 Mar 1984, 25°04'S 46 ° 26 '00''W, 65 m, muddy-sand; 1 spec. (MCEM- BPO 278), coll. 13 Nov 1985, 25°04'S 46 ° 26 '00''W, 65 m, muddy-sand; 1 spec. (MCEM-BPO 277), coll. 4 Nov 1985, 25° 55 'S 47 ° 52 '03''W, 49 m, muddy-sand; 1 spec. (AM W 34750), coll. 3 Nov 1985, 26° 22 'S 48 ° 19 '08''W, 49 m, muddy-sand; 2 specs (MCEM-BPO 276), coll. 3 Nov 1985, 26° 22 'S 48 ° 19 '08''W, 49 m, muddy-sand; 2 specs (MCEM-BPO 273), coll. 17 Mar 1984, 26° 22 'S 48 ° 19 '08''W, 49 m, muddy-sand. Type series. Information on each specimen of the type series is provided in Table 1. Slides: Holotype (MZUSP 00950): notochaetae from segments 5 and 17; neurochaetae from segments 8, 10, 11, 21, and 63. Comparative material examined. Pista alonsae Santos, Nogueira, Fukuda & Christoffersen, 2010. Holotype (MZUSP 01036), paratypes 1 (CIPY-POLY- 1396), 2 (CIPY-POLY- 1397), 3 (CIPY-POLY- 1398), and 4 (LACM- AHF POLY 2263) coll. 9 Nov 2007, Brazil, Rio Grande do Norte, Macau, 05°04’S 36 ° 27 ’W; slides: holotype: notochaetae from segments 8 and 17, neurochaetae from segments 5, 10, 11, 13, and region with neuropodia only; paratype 2: neurochaetae from segments 5, 10, 11, and 20. Paratype 5 (LACM-AHF POLY 2258) coll. 10 Nov 2007, Brazil, Rio Grande do Norte, Macau, 05°04’S 36 ° 28 ’W. Paratypes 6 (MZUSP 01037) and 7 (CIPY-POLY- 1399) coll. 9 Nov 2007, Brazil, Rio Grande do Norte, Macau, 05°04'S 36 ° 27 'W. Paratypes 8 (MZUSP 01038) and 9 (ZMUC Pol 2109) coll. 9 Nov 2007, Brazil, Rio Grande do Norte, Macau, 05°04’S 36 ° 26 ’W. Pista cetrata (Ehlers, 1887, as Terebella cetrata). Holotype (MCZ 834), coll. USA, Florida, Key West, 2–4 m, Blake Expedition, by A. Agassiz, 1877–1878; incomplete spec., in relatively good state of preservation. Slides: notochaetae from segment 18; neurochaetae from segments 6, 13, 23, 61. Pista corrientis McIntosh, 1885. Holotype (BMNH 1885.12.1.348): coll. South Atlantic, Argentina, off the mouth of Rio de la Plata (37 o 17 ’S 53 o 52 ’W), in sea bottom with green sand, ~ 1100 m (600 fm), Challenger Expedition, 14 Feb 1876; complete spec., in poor state of preservation but most of important characters still visible; all notochaetae broken. Slides: neurochaetae from segments 9, 19, 23 and 83. Pista cristata (Müller, 1776). Non-type material. ZMUC Pol 707: coll. North Atlantic Ocean, Denmark, off Laesø, W edge of Kummelbankens, 39–43 m, stones and mud, R/V Ophelia dredge 72, by C. Nielsen, 7 Jul 1960; 2 specs in relatively good state of preservation, all posteriorly incomplete; slides: notochaetae from segments 6 and 19; neurochaetae from segments 5–11, 14, and anterior segment of region with neuropodia only. ZMUC Pol 2054: coll. North Atlantic Ocean, Denmark, Frederikshavn, soft bottom, by H. Ditlevsen, 15 Jul 1927; 3 specs in relatively good state of preservation, all posteriorly incomplete and partially inside the tubes. ZMUC Pol 2055: coll. North Atlantic Ocean, Denmark, Laesø Rende, 30 m, Biological field course, 29 Jul 1947; 3 specs in poor state of preservation, 2 of them inside the tubes. ZMUC Pol 2056: coll. North Atlantic Ocean, Denmark, Frederikshavn, Biological field course, 1 Aug 1947; 6 specs in relatively good state of preservation, 4 of them partially inside the tubes. Pista palmata (Verrill, 1873, as Scionopsis palmata). Non-type material. USNM 090608: coll. North Atlantic Ocean, Gulf of Mexico, USA, Texas, off Port Isabel (26 o 10 ’N 97 o08’W), 15 m, BLM, Sta IV- 4, STOCS, winter 1977; incomplete spec., in relatively poor state of preservation. USNM 090611: coll. North Atlantic Ocean, Gulf of Mexico, USA, Texas, off Port Isabel (26 o 10 ’00”N 97 o08’00”W), 15 m, BLM, Sta S- 53, IXTOC, Dec 1980; fragment in very poor state of preservation. USNM 090610: coll. North Atlantic Ocean, Gulf of Mexico, USA, Texas, off Port Isabel (26 o 10 ’N 97 o08’W), 15 m, BLM, Sta IV- 4, ves: STOCS, fall 1983; 2 specs, one complete and tiny, other incomplete, both in very poor state of preservation. Slides: spec. USNM 0 90610 (incomplete spec.): notochaetae from segments 6 and 18; neurochaetae from segments 5, 11, 27. Pista sombreriana McIntosh, 1885. Holotype (BMNH 1885. 12.1.344): coll. North Atlantic Ocean, Caribbean, off Sombrero and St. Thomas, Challenger Expedition; incomplete spec. in very poor state of preservation, in three pieces, anterior piece further cut in two halves along longitudinal midline. Slides: notochaetae from segment 14; neurochaetae from segments 6, posterior segment of region with biramous parapodia and anterior segment of region with neuropodia only (the state of preservation of the specimen precludes counting of segments). Description. Thick mucous tube, with embedded sand, coarse gravel and fragments of shells (Fig. 3 A). Complete specimens up to 61 mm long, 3 mm wide, up to 92 segments. Preserved body beige to light brown (Fig. 3 A– K), live specimens frequently with darker pigmentation on lobes and around neuropodia. Body not dorsally inflated anteriorly (Figs. 3 A–F; 4 B–D, H–I); anterior segments compact, about same length, segments progressively longer on segments 8–20, elongation more evident from segment 11 (Figs. 3 A–F; 4 A–D, H–K). Ventral shields on segments 2–20, smooth, rectangular, progressively wider until segment 4, then progressively narrower until segment 8, about same width on segments 9–16, then progressively narrower again until segment 20; shields progressively longer on segments 6–16, about same length on segments 17–19, last shield distinctly shorter (Figs. 3 A–B, I–J; 4 A, J–K); after segment 20 shields replaced by mid-ventral groove extending posteriorly. Prostomium at base of upper lip; distal part forming shelf-like process from which buccal tentacles originate (Figs. 3 D, F, J–K; 4 D–I); no eyespots on basal part of prostomium. Peristomium restricted to lips; upper lip short, distinctly wider than high; lower lip short, cushion-like, partially covered by lobes on segment 1 (Figs. 3 B, D, F, I–K; 4 A, E–G, J–K). Segment 1 narrow, with one pair of large, distally rounded lobes originating dorso-laterally, extending anteriorly and ventrally, reaching beyond level of upper lip, connected to each other by lower mid-ventral membrane partially exposing lower lip (Figs. 3 A–F, I–K; 4 A–K). Segment 2 dorsally and laterally short, longer ventrally, with one pair of short and rounded ventro-lateral lobes, connected to each other by low membrane across ventrum (Figs. 3 B–C, E, I–K; 4 A–K). Segment 3 with one pair of large, distally rounded lobes originating dorsally to level of notopodia on segment 4, near dorsal mid-line, and terminating at level of lateral margin of ventral shields (Figs. 3 A–F, I–K; 4 A–K); anterior margin of segment 3 forming mid-dorsal crest (Fig. 4 C, I). Segment 4 with short lateral lobes, as thin flaps, connected to each other by dorsal crest on anterior margin of segment (Figs. 3 A–F, I–K; 4 A–E, G–K); segments 5– 6 with short ventro-lateral lobes as low flaps between ventral shields and neuropodia (Figs. 3 E, I–J; 4 A–B, D–E, H, J–K). Two pairs of branchiae on segments 2–3, with long, irregularly annulated basal stem and secondary branches originating all at same level and about same length (Figs. 3 B–F, I, K; 4 B–I, K). Seventeen pairs of notopodia, starting from segment 4 and extending until segment 20, all about same size; notopodia of segments 4–7 inserted progressively more laterally, then vertically aligned (Figs. 3 A–F, K; 4 B–E, H–I, K). Broadly winged notochaetae on both tiers, wing distinctly broader on one margin, those on posterior tier with limbation starting from mid-length of chaetae (Fig. 5 A, D); anterior notopodia with notochaetae of posterior tier about twice as long as those on anterior tier (Fig. 5 A, D). Neuropodia starting from segment 5, as low rectangular ridges slightly raised from surface of body until segment on which notopodia terminate (Figs. 3 A–F, I–K; 4 B, D, H, K), as short pinnules on anterior part of region with neuropodia only (Figs. 3 G; 4 L), longer on posterior body segments (Fig. 3 H); neuropodial pinnules situated laterally on body, well separated from mid-ventral groove, internal neuropodial shafts present (Figs. 3 G– H; 5 C, F). Long-handled uncini on segments 5–10, with thin handle originating from heel (Fig. 5 E), short-handled thereafter (Fig. 5 B–C, F–G); uncini with distally rounded prow, dorsal button situated at mid-length between base of main fang and tip of prow, and crest with ~ 4 rows of secondary teeth (Figs. 5 E; 6 A–B), on anterior neuropodia, 3–4 rows on segments 11–20, only visible under SEM (Figs. 5 B; 6 C); uncini arranged in completely intercalated double rows from segment 11 until segment on which notopodia terminate (Figs. 5 B; 6 C); from segment 21, uncini similar to those from anterior neuropodia, but short-handled and with inconspicuous dorsal button (Figs. 5 C, F–G; 6 D). One pair of large nephridial papillae on segment 3, inserted dorsally to bases of lobes, genital papillae situated posteriorly and dorsally to notopodia on segments 6–7 (Figs. 3 C–F; 4 C, H–I, K). Pygidium smooth. Variation. Branchiae are easily lost and regenerated in this species. Frequently at least one of the branchiae is missing and they often differ in size within the same pair (Fig. 3 B–F, K). Most specimens have the first pair of branchiae longer than those of the second pair, but some specimens have the second pair of branchiae longer, possibly due to regeneration of the first pair. Most specimens have branchiae as described above, with secondary branches originating together and about the same length, but paratype 2 has arborescent branchiae, with secondary branches originating at different points along the main stem and unequal in length (Table 1). Remarks. Santos et al. (2010) made an extensive comparison between Pista alonsae Santos, Nogueira, Fukuda & Christoffersen, 2010 and all other species of Pista previously reported for Brazilian and Caribbean waters. Therefore, to avoid repetitions, in this paper we include a comparative table for all those species of Pista discussed by Santos et al. (2010) (Table 2), and only provide further discussion on the similarities and differences between P. nonatoi spec. nov., P. alonsae and P. corrientis. Holotype Paratype 1 Paratype 2 Paratype 3 Paratype 4 Paratype 5 Paratype 6 Paratype 7 Paratype Paratype 9 Paratype MZUSP ZUEC- MZUSP USNM ZUEC- LACM- MZUSP ZUEC- 8 LACM- 10 USNM 0 0 950 POL 9606 0 0 951 1155161 POL 9607 AHF Poly 0 0 952 POL 9608 MZUSP AHF Poly 1155160 2695 0 0 953 2696 Collection Praia de Praia de Ilha das Pal- Offshore Uba- Offshore Offshore Offshore Praia de Praia de Ilha das Praia de data Martim de Picingu- mas tuba Ubatuba Ubatuba Ubatuba São Fran- Picingu- Palmas Picinguaba Sá (23 ° 37 'S aba (24 °00'S (23 º 32 ' 539 ''S (23 º 25 ' 785 '' (23 º 25 ' 785 '' (23 º 48 ' 240 ' cisco aba (24 °00'S (23 ° 22 'S 45 ° 22 'W), (23 ° 22 'S 46 ° 19 'W), 45 º05' 409 ''W), S S 'S (23 ° 44 'S (23 ° 22 'S 46 ° 19 'W), 44 ° 50 'W), Caraguata- 44 ° 50 'W), Santos, state state of São 44 º 46 ' 738 '' 44 º 46 ' 738 '' 45 º 10 ' 124 '' 45 ° 24 'W), 44 ° 50 'W), Guarujá, Ubatuba, tuba, state of Ubatuba, of São Paulo, fine W), state of W), state of W), state São Ubatuba, state of São state of São São Paulo, state of Paulo, inter- sand, 15.4 m, São Paulo, São Paulo, of São Sebastião, state of Paulo, Paulo, shalshallow sub- São Paulo, tidal, on 23 Mar 2002 medium medium Paulo, fine state of São São Paulo, intertidal, low subtidal, in shallow rocky shore, sand, 35 m, sand, 35 m, sand, 30 m, Paulo, shallow on rocky tidal, in algae, 16 subtidal, 0 5 Oct 2005 17 Mar 2001 17 Mar 20 May intertidal, subtidal, shore, 0 6 algae, 18 Mar 2001 in algae,0 8 2001 2002 on rocky in algae, Mar 2004 Oct 2001 Jun 2001 shore, 24 0 8 Jun Jul 2005 2001 Size (mm) 38.5; 3 / 53 24.5; 2 / 41 11.2; 1 / 60 19.2; 2 / 40 13; 1.7/ 32 17.5; 1.8/ 11; 1 / 71 14.5; 1.5/ 14; 2 / ~ 38 25; 2.2 / 46 11.5; 2.1/ (length; (incomp.) (incomp.) (incomp.) ~ 50 ~ 50 (incomp.) (incomp.) ~ 25 width/ (incomp.) (incomp.) (incomp.) number of segments) Branchiae (left/right) 1 st pair Missing; Missing; Very short; Missing; large Missing; Missing; Missing; Large; Large; Large; Missing; short missing short large large missing short large large large Missing; miss- 2 nd pair Missing; Short; large ing Large; short Large; Short; Large; Large; Short; large Large; Large; short short missing large large large short Additional Incomplete Incom- Complete Incomplete Incomplete Incomplete Complete Incomplete Incom- Incom- Incominforma- spec., in plete spec., spec. in spec., in good spec., in spec., in spec., in spec., in plete spec., plete spec., plete spec., tion good state of in good good state state of preser- good state of good state good state good state in good in good in good preservation state of of preserva- vation preservation of preserva- of preser- of preser- state of state of state of preserva- tion, but tion vation, vation, pos- preserva- preserva- preserva- tion smaller than possibly a sibly a tion tion tion other specs. juvenile juvenile Arborescent branchiae, with second- ary branches originating at different levels and of different lengths Specimens of Pista nonatoi spec. nov., have previously been assigned to P. corrientis by several Brazilian researchers. That species differs from P. nonatoi spec. nov., in having short lobes on segment 1 that do not reach the level of the tip of upper lip; distinctly smaller lobes on segment 3 that originate at the level of the notopodia on segment 4 and terminate at the level of the ventral edge of the neuropodia, well separated from ventral shields; uncini throughout with 3 rows of secondary teeth; long-handled uncini on segments 5–20; and nephridial papillae on segment 3 inserted dorsal to the bases of the branchial stems. Pista nonatoi sp. nov., by contrast, has lobes on segment 1 that extend beyond the level of the upper lip and cover the anterior end; lobes on segment 3 that originate dorsal to the level of the notopodia on segment 4, near the dorsal mid-line, and terminate at the level of the lateral margin of the ventral shields (compare Fig. 1 A–C, F–L with Figs. 3 A–F, I–K; 4 A–K); uncini with 3–4 rows of secondary teeth on segments 11–20 and ~ 4 rows on segments 5–10 and from 21 onwards; long-handled uncini present only on segments 5–10; and nephridial papillae on segment 3 inserted dorsal to the bases of the lobes on segment 3 and ventral to the bases of branchial stems. Pista alonsae is the species most similar morphologically to Pista nonatoi spec. nov., differing from the latter species by its dorsolaterally indented lobes on segment 3; ventral shields present on segments 2–16; uncini throughout with 3–4 rows of secondary teeth; and long-handled uncini on segments 5–20. In contrast, P. nonatoi spec. nov., has ventral shields on segments 2–20, uncini on segments 11–20 with fewer rows of secondary teeth than on the remaining parts of the body, and long-handled uncini present only on segments 5–10. P. cretacea coded after Fauvel 1927; P. fasciata, P. quadrilobata, Pista sp. A and B coded after Kritzler 1984; P. herpini after Fauvel 1928). ..... continued on the next page..... continued on the next page It is uncertain if Hartman’s description of P. corrientis for specimens from Antarctica corresponds to P. nonatoi spec. nov. The author did not mention several characters currently considered important for the taxonomy of the group. For example, Hartman (1966) did not mention the presence of lobes on segments 2 and 4–6, nor were they illustrated in the figure of the anterior end in ventral view (Hartman 1966: 98, Pl. XXXIII, fig. 4). In addition, she did not provide any information on the morphology of the lobes on segment 3, nor mention the number of secondary rows of teeth on the uncinial crest on each part of the body. Also, according to the figure cited above, the lobes on segment 1 do not reach beyond the level of the upper lip. Etymology. This species is dedicated to Professor Edmundo Ferraz Nonato, from Instituto Oceanográfico, Universidade de São Paulo, who first identified this taxon in Brazilian waters, and in honor of his role as the foremost Brazilian polychaete researcher. Professor Nonato is the academic father, grandfather, and even great-grandfather of every Brazilian polychaete researcher working today.Published as part of Nogueira, João Miguel De Matos, Harris, Leslie, Hutchings, Pat & Fukuda, Marcelo Veronesi, 2011, Four terebellines (Polychaeta, Terebellidae) with problematic taxonomic histories, pp. 1-26 in Zootaxa 2995 on pages 6-16, DOI: 10.5281/zenodo.27841
Relationship between Sulfur Dioxide Concentration and Meteorological Condition in Mizushima Industrial DistrictReport 1 (Relationship among Sulfur Dioxide Concentration and Wind Derection, Wind Velocity and Atmospheric Stability)
No full textThe author calculated the frequency of high concentration of sulfur dioxide (over 0.2 p. p. m.) in one hour according to wind direction, wind velocity and Pasquill's stability, and the author also calculated the average concentration of sulfur dioxide according to wind direction and velocity. The results obtained were as follows; 1. S, SSW, SW, and WSW winds (mainly sea breeze) bring the air pollutant to the northern part in Mizushima Industrial Area. Wind direction and wind velocity that brings. a higher concentration of sulfur dioxide to Fukuda-cho, Minami Kasuga-cho, and Amagi were S, SW, and SSW winds of 3～4 M/sec. In Mizushima Harbour Office, high sulfur dioxide concentartions were measured in S, SW, 2～3 M/sec. and SW, 2～5 M/sec. Average sulfur dioxide concentrations were higher in S, SW, 2～4 M/sec. in Fukuda-cho, Minami Kasuga-cho and higher in SSE 6 M/sec., SSW 6～7 M/sec., SW 2～5 M/sec., and S 3 M/sec. in Mizushima Harbour Office. 2. Unstable sea breeze brings higher concentrations of sulfur dioxide to Fukuda-cho and more stable sea breeze brings higher concentrations to Amagi.
From the calculations of diffusion by Pasquill's chart it was shown that the diffusion in C-stability brings high concentrations of sulfur dioxide to Fukuda-cho, and the diffusion in D-stability brings to Amagi
Cosmological parameter estimation using Very Small Array data out to ℓ= 1500
No full textWe estimate cosmological parameters using data obtained by the Very Small Array (VSA) in its extended configuration, in conjunction with a variety of other cosmic microwave background (CMB) data and external priors. Within the flat Λ cold dark matter (ΛCDM) model, we find that the inclusion of high-resolution data from the VSA modifies the limits on the cosmological parameters as compared to those suggested by the Wilkinson Microwave Anisotropy Probe (WMAP) alone, while still remaining compatible with their estimates. We find that Ωbh2= 0.0234+0.0012−0.0014, Ωdmh2= 0.111+0.014−0.016, h= 0.73+0.09−0.05, nS= 0.97+0.06−0.03, 1010AS= 23+7−3 and τ= 0.14+0.14−0.07 for WMAP and VSA when no external prior is included. On extending the model to include a running spectral index of density fluctuations, we find that the inclusion of VSA data leads to a negative running at a level of more than 95 per cent confidence ( nrun=−0.069 ± 0.032 ), something that is not significantly changed by the inclusion of a stringent prior on the Hubble constant. Inclusion of prior information from the 2dF galaxy redshift survey reduces the significance of the result by constraining the value of Ωm. We discuss the veracity of this result in the context of various systematic effects and also a broken spectral index model. We also constrain the fraction of neutrinos and find that fν < 0.087 at 95 per cent confidence, which corresponds to mν < 0.32 eV when all neutrino masses are equal. Finally, we consider the global best fit within a general cosmological model with 12 parameters and find consistency with other analyses available in the literature. The evidence for nrun < 0 is only marginal within this model
Predictive value of inflammation-based prognostic scores in patients with metastatic renal cell carcinoma treated with cytoreductive nephrectomy
No full text東京女子医科大学博士(医学)博士(医学) 甲第694号(主論文の要旨、要約、審査結果の要旨、本文)，著者名:Hironori FUKUDA・ Toshio TAKAGI・Tsunenori KONDO・Satoru SHIMIZU・Kazunari TANABE，タイトル:Predictive value of inflammation-based prognostic scores in patients with metastatic renal cell carcinoma treated with cytoreductive nephrectomy，掲載誌:Oncotarget(1949-2553)，巻・頁・年:9巻18号 p.14296-14305(2018)，著作権関連情報:Copyright: Fukuda et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.，DOI:10.18632/oncotarget.24507doctoral thesi
Predictive value of inflammation-based prognostic scores in patients with metastatic renal cell carcinoma treated with cytoreductive nephrectomy
No full text博士(医学) 甲第694号(主論文の要旨、要約、審査結果の要旨、本文)，著者名:Hironori FUKUDA・ Toshio TAKAGI・Tsunenori KONDO・Satoru SHIMIZU・Kazunari TANABE，タイトル:Predictive value of inflammation-based prognostic scores in patients with metastatic renal cell carcinoma treated with cytoreductive nephrectomy，掲載誌:Oncotarget(1949-2553)，巻・頁・年:9巻18号 p.14296-14305(2018)，著作権関連情報:Copyright: Fukuda et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.，DOI:10.18632/oncotarget.2450
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