292 research outputs found
The use of photobiomodulation therapy for the management of chemotherapy-induced alopecia: a randomized, controlled trial (HAIRLASER trial)
No full textPurpose: The purpose of this trial was to evaluate if photobiomodulation (PBM) can accelerate hair regrowth after chemotherapy in breast cancer patients and if this is correlated with a better quality of life (QoL).
Methods: A randomized controlled trial with breast cancer patients that underwent an anthracycline and taxane-containing chemotherapy regimen was set up at the Jessa Hospital (Hasselt, Belgium). Patients were randomized into the control group (no intervention) or the PBM group (three PBM sessions each week for 12 weeks, starting the last day of their chemotherapy). Hair regrowth was evaluated based on photographic assessments. Two blinded researchers independently scored the hair regrowth using a numerical rating scale (NRS). In addition, the QoL was measured using the European Organization for Research and Treatment-QOL questionnaire and Breast Cancer-specific module (EORTC QLQ-C30 and QLQ-BR23). Data were collected on the day of their last chemotherapy session and 1, 2, and 3 months post-chemotherapy.
Results: A total of 32 breast cancer patients were included in the trial between June 2020 and February 2022. Significantly higher NRS scores were observed in the PBM group at 1-month post-chemotherapy compared to baseline, whereas they remained constant in the control group. Patients allocated to the PBM group scored their global health significantly higher at all time points compared to the control.
Conclusion: Based on the results of the HAIRLASER trial, PBM seems to accelerate hair regrowth after chemotherapy in breast cancer patients resulting in an improved global health status and better body image. The study was registered in July 2019 at ClinicalTrials.gov (NCT04036994).Funding
This research is funded by the Limburg Clinical Research Center (LCRC) UHasselt-ZOL-Jessa, Kom op tegen Kanker (Stand up to Cancer), the Flemish cancer society, Live a Life, and the Limburgs Kankerfonds.
Acknowledgments
This research is part of the Limburg Clinical Research Center (LCRC) UHasselt-ZOL-Jessa, supported by the Limburg Sterk Merk Foundation, province of Limburg, Flemish government, Hasselt University, Jessa Hospital, and Ziekenhuis Oost-Limburg.l This research is approved by the ethics committees of the Jessa Hospital and the University of Hasselt (B243201940887)
R v Secretary for the Home Department, ex parte Pierson [1998] AC 539, House of Lords
No full textEssential Cases: Public Law provides a bridge between course textbooks and key case judgments. This case document summarizes the facts and decision in R v Secretary for the Home Department, ex parte Pierson [1998] AC 539, House of Lords. The document also includes supporting commentary from author Thomas Webb.</p
The Fugitive
No full textTelevision’s longest-running chase story, The Fugitive was a dramatically charged show that followed Dr. Richard Kimble on his quest to prove his innocence and find his wife’s one-armed killer. A product of veteran television producer-writer Roy Huggins (Maverick, The Rockford Files) and Quinn Martin, a newcomer producer, the series aired for four seasons between 1963 and 1967 on the ABC network. In The Fugitive, author David P. Pierson examines the creation of the series and its dominant social discourses and themes, along with the industry producers, writers, and actors who made it one of the most memorable and influential shows in 1960s American television.
In The Fugitive, Pierson discusses the context of the series’ creation at a time when federal regulators were forcing the three major television networks to broadcast adult programs with less physical violence. Pierson also offers a unique analysis of the major themes represented in The Fugitive’s episodes, such as individualism, love and marriage, the culture of professionalism, modern science and technology, and social justice and authority, along with how these themes connected to ongoing social and cultural struggles taking place in American society in the 1960s. The book explores the reasons why The Fugitive was so popular with audiences of the 1960s, and suggests that one of the strongest appeals of the series is the memorable, poignant performance by David Janssen as Richard Kimble. Pierson also argues that The Fugitive established the narrative and thematic grounds for the wanderer-redeemer television tradition, whose influence he links to later series like Run for Your Life, Then Came Bronson, The Incredible Hulk, Highway to Heaven, Quantum Leap, and Touched by an Angel. Pierson concludes by examining the similarities and differences between The Fugitive and the 1993 feature film based on the series.
After a finale that held the record for the highest share of American homes with television sets tuned in, the series ended, but not without creating a cultural and programming legacy. Fans of the show and scholars of television history and American popular culture will enjoy this informative study.https://digitalcommons.usm.maine.edu/facbooks/1232/thumbnail.jp
Navigating the waters around "wicked problems": perspectives on misconduct from COPE
No full textPresented at the Retractions conference: keeping the pool clean: prevention and management of misconduct related retractions held on July 20-21, 2016 at Hilton Fort Collins in Fort Collins, Colorado.Charon Pierson is the Secretary of the Council and Trustee Board for the Committee on Publication Ethics (COPE). She is a geriatric nurse practitioner with a PhD in Medical Sociology and post-doctoral education in gerontology. She has taught geriatrics to nursing and medical students as faculty at California State University Long Beach, University of Hawaii, and University of Texas El Paso (UTEP) and also served as the Director of the Center for Aging at UTEP. Retired after 30 years in academia, she now consultants at universities and schools on the development of geriatric-related content for online courses and graduate programs and lectures widely on publication ethics. Since 2000 she has been the editor-in-chief of the Journal of the American Association of Nurse Practitioners, a monthly, peer-reviewed scholarly journal indexed in the Web of Science. She has served on the COPE Council since 2012.PowerPoint presentation given on Day 2: Thursday, July 21st, 2016.Includes bibliographical references.This conference was funded by the Office of Research Integrity, U.S. Department of Health and Human Services, grant #ORIIR150014
Repairing what's not broken - Algorithm repair manual as reflexivity device
No full textThe author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by the Fonds Wetenschappelijk Onderzoek; G054919N
Megne, Lilly Maud (Death, 1882-12-01)
No full textAddress: 5th & Pierson St.Age at death: 4 daPg 188/1882/32/F W S/City/Dr. Freeman/Finn/Mt. WashingtonOriginal record filed in drawer labeled 'MAYERHOEFER-MEIFERT'
Patient-Centred Outcomes after Totally Endoscopic Cardiac Surgery: One-Year Follow-Up
No full textPatient-centred outcomes have grown in popularity over recent years in surgical care research. These patient-centred outcomes can be measured through the health-related quality of life (HRQL) without professional interpretations. In May 2022, a study regarding patient-centred outcomes up to 90 days postoperatively was published. Fourteen days after surgery, the HRQL decreased and returned to baseline levels after 30 days. Next, the HRQL significantly improved
90 days postoperatively. However, this study only focuses on a short-term follow-up of the patients. Hence, this follow-up study aims to assess the HRQL one year after totally endoscopic cardiac surgery. At baseline, 14, 30, and 90 days, and one year after surgery, the HRQL was evaluated using a 36-item short form and 5-dimensional European QoL questionnaires (EQ-5D). Using the 36-item short form questionnaire, a physical and mental component score is calculated. Over the period of one year, this physical and mental component score and the EQ-5D index value significantly improve. According to the visual analogue scale of the EQ-5D, patients score their health significantly higher one year postoperatively. In conclusion, after endoscopic cardiac surgery, the HRQL is significantly improved 90 days postoperatively and remains high one year afterward
Ultrasound-guided axillary brachial plexus block <i>versus</i> distal peripheral forearm nerve block for hand and wrist surgery: a randomised controlled trial
No full textstatus: Publishe
90-Day Patient-Centered Outcomes after Totally Endoscopic Cardiac Surgery: A Prospective Cohort Study
No full textOver the past years, minimally invasive procedures have been developed to reduce surgical trauma after cardiac surgery. The value of patient-centered outcomes, including the quality of recovery after hospital discharge, is increasingly recognized. Identifying meaningful changes in postoperative function that might have a negative impact on patients without noticeable complications can provide a more comprehensive understanding of the impact on the patient’s life. In total, 209 patients were included in this trial. Of these, 193 patients underwent totally endoscopic cardiac surgery, 8 underwent cardiac surgery through a sternotomy, and 8 underwent transcatheter aortic valve implantation. Patients who previously underwent cardiac surgery were excluded. Quality of life was determined through the Short Form 36 and European Quality of Life-5 Dimensions questionnaires before the surgery and 14, 30, and 90 days afterward. In patients who underwent totally endoscopic cardiac surgery, the quality of life improved over the three time periods. The different domains of the questionnaire evolved in a positive manner. However, 14 days postoperatively, a decline in quality of life was noted, followed by a return to baseline at 30 days and an increase at 90 days. In conclusion, totally endoscopic cardiac surgery improves the quality of life 90 days after surgery
The Politics of Protest Avoidance: Policy Windows, Labor Mobilization, and Pension Reform in France
No full textAccording to Paul Pierson and R. Kent Weaver, the "new politics of the welfare state" is about escaping the popular blame generated by cutbacks affecting a significant portion of the population. Although the concept of blame avoidance helps to explain the political logic of welfare state retrenchment, one can argue that a careful analysis of social policy reform should take into account a largely understudied phenomenon: protest avoidance. Especially present in countries with single party governments and politically active labor unions, protest avoidance is analytically distinct from blame avoidance because it occurs when policy-makers, facing direct and nearly inescapable blame, attempt to reduce the scope of social mobilization triggered by unpopular reforms. In recent decades, successive French governments have successfully introduced major--and unpopular--reforms in the field of pensions, despite the difficulties to frame blame avoidance strategies in the context of France's strong concentration of state power. Focusing on the 1993, 1995, and 2003 pension reform episodes, this paper seeks to demonstrate that right wing governments have generally tried to avoid protest rather than escape blame. We claim that the key element has been avoiding disruptive strike activities by the labor movement, which are highly political in France. We argue that right wing governments have attempted to divide the fragmented labor movement and overload the reform agenda while enacting its most controversial reforms during the summer holiday season. Protest avoidance thus represents a key political variable worthy of study in the literature on welfare state retrenchment. In the future, the concept of protest avoidance could be applied to other countries and policy areas in which elected officials attempt to impose unpopular reforms that trigger social mobilization.protest avoidance; pension reform
- …
