568 research outputs found
A secret radical enlightener in 1770s Copenhagen:Peter Frederik Suhm
No full textPeter Frederik Suhm was a historian and independent author in Denmark-Norway in the latter half of the eighteenth century. Mostly known for his extensive work as an author of historical works and fictions, he also developed a less known political doctrine through the 1760–70s, developing radical enlightenment ideas. These ideas culminated around the Danish Press Freedom Period 1770–3 and involved ideas such as freedom of speech and religion, rule of law, constitutional monarchy, an elected parliament, separation of powers, etc. — much of which were not or only partially published at the time. This paper investigates Suhm’s radical political philosophy.</p
Willem Frederik Hermans
No full textBronze head created by the Dutch artist Sylvia Willink-Quiel (1944- ), probably a later copy. It belongs to the "Nederlandse Kultuur Historiese Instituut" at the University of Pretoria.
Photograph taken postcard size with Kodak camera 150dpi. Photograph edited due to quality of lightingBronze head of the Dutch author Willem Frederik Hermans (1921-1995), one of the most important Dutch writers in post World War 2 Netherlandshttp://nl.wikipedia.org/wiki/Willem_Frederik_Herman
Navigating the risks in acute heart failure
No full textThe author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: FHV is supported by a fellowship of the Belgian American Educational Foundation (BAEF) and by the special research fund (BOF) of Hasselt University (BOF19PD04).Verbrugge, FH (corresponding author), Hasselt Univ, Biomed Res Inst, Fac Med & Life Sci, Campus Diepenbeek,Agoralaan Gebouw D, Diepenbeek, Belgium.
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More on the chronology of Celtic sound changes
No full textGraham Isaac’s recent monograph (2007) deals with the chronology of Celtic sound changes. Remarkably, the author completely disregards the relative chronology which I published 28 years earlier (1979). In the following I shall discuss the main issues on which our views differ
Prototyp für ein mobiles Agentensystem in Nl LabVIEW
No full textOnTEAM metadata: GDSID: DOC-2011-Mar-16; Attribute ID: LIBRARY-thesis_diplom-2011-002; Title: [GSI Dipl 2010-05] Prototyp für ein mobiles Agentensystem in Nl LabVIEW [06.04.2010]; Author(s): Berck, Frederik; Corporate author(s): ; Publication date: 20110303; Creator: manton; Creation date: 03.03.2011 15:21:01; Change date: 03.03.2011 15:52:21; Access: Welt; Attribute type: Thesis.Diplom; Directory path: ['GSI Publications', 'GSI as Publisher']; Attribute path: ['Infrastructure', 'Library and Documentation', 'thesis_diplom', 'Added in 2011']; File name(s): ['DOC-2011-Mar-16-1.pdf']; File title(s): ['']; File access: ['nur berechtigte Gruppen'
Klimaatimpact op de binnenvaart vraagt om samenwerking en een systemische aanpak
No full textVeel mensen herinneren zich de droge periode uit 2018 en het hoge water op de Maas. Deze events hadden een grote impact op de scheepvaart en uiteindelijk op de levering van goederen in verschillende Europese landen. Dit soort events zullen in de toekomst vaker optreden en grote gevolgen hebben voor de totale samenleving en de economie. Het hebben van goede strategieën en maatregelen om de impact van dit soort events te beperken, vraagt om een gedegen aanpak en onderzoek. Frederik Vinke, promovendus binnen de vakgroep Ports and Waterways (TU Delft), ondersteund door SmartPort, past een nieuwe methodiek toe waarbij de interactie tussen de rivier en de scheepvaart op een systemisch niveau wordt gemodelleerd. Tegelijkertijd worden op micro niveau de schepen met eigen vervoersopdrachten gemodelleerd.Rivers, Ports, Waterways and Dredging Engineerin
Baltų-slavų rekonstrukcija: paaiškinimas
No full textStraipsnyje, atsiliepiant į Miguelio Villanueva‘os Svenssono recenziją (Villanueva Svensson, Miguel 2010 (rev.), Frederik Kortlandt, Baltica & Balto-Slavica 2009, Baltistica 45(2), 359–364), autoriaus yra komentuojama ir aiškinama keletas veikale „Baltica & Balto-Slavica“ (Amsterdam: Rodopi, 2009) jo aptartų rekonstrukcijų: indoeuropiečių tematinio esamojo laiko trečiojo asmens daugiskaitos galūnės *-o virtimas lietuvių -a, prūsų -a bei indoeuropiečių o kamieno daugiskaitos kilmininko galūnės *-om virtimas lietuvių -ų, prūsų -on. Reikšminiai žodžiai: Baltų kalbos; Slavų kalbos; žodžių galūnių rekonstrukcija; Baltic languages; Slavic languages; Reconstruction of words endingsThe article by the author, in response to a review by Miguel Villanueva Svensson (Villanueva Svensson, Miguel 2010 (rev.), Frederik Kortlandt, Baltica & Balto-Slavica 2009, Baltistica 45(2), 359–364), comments and explains several reconstructions discussed in the work Baltica & Balto-Slavica (Amsterdam: Rodopi, 2009): transformation of Indo-European thematic present tense third person plural ending *-o into Lithuanian -a, Prussian –a, as well as transformation of Indo-European stem plural genitive case ending *-om into Lithuanian -ų, and Prussian -on
Spektroskopische Diagnose eines Röntgenlaserplasmas
No full textOnTEAM metadata: GDSID: DOC-2007-Jul-121; Attribute ID: LIBRARY-thesis_diplom-2007-009; Title: [GSI Dipl 2007-06] Spektroskopische Diagnose eines Röntgenlaserplasmas [30.05.2007]; Author(s): Zimmer, Daniel Frederik; Corporate author(s): ; Publication date: 20070717; Creator: manton; Creation date: 17.07.2007 15:34:01; Change date: 30.09.2010 16:40:55; Access: Welt; Attribute type: Thesis.Diplom; Directory path: ['GSI Publications', 'GSI as Publisher']; Attribute path: ['Infrastructure', 'Library and Documentation', 'thesis_diplom', 'Added in 2007']; File name(s): ['DOC-2007-Jul-121-1.pdf']; File title(s): ['']; File access: ['GSI-intern'
Henning Høirup: Frederik Lange Grundtvig
No full textFrederik Lange Grundtvig. By Henning Høirup, in collaboration with M. F. Blichfeld, Inger M. Boberg, and Hans E. Eriksen. By Gustav Albeck. It is more than a mere work of piety that Dean Høirup has performed in publishing this comprehensive book about Grundtvig’s youngest son. It appeared on the occasion of the centenary of Frederik Lange Grundtvig’s birth, but it is something other and more than a tribute to his memory. Dr. Høirup has taken charge of its publication and has written the greater part of the text, but has supplimented his own presentation of the subject with contributions from other writers. Thus the Rev. M. F. Blichfeld, who was a Danish clergyman in the U.S.A. and has now retired, has written Chapter V and VI of the book, which deal with F. L. Grundtvig’s activities in the Danish Church in America and his national work among Danish people there (1883—1900) and with his last tragic years (1900—1903), while Dr. Inger M. Boberg (who has since died) writes, with specialist knowledge and not without admiration, about F. L. Grundtvig’s comprehensive and original contribution as a collector of folk traditions. But the most important part of the book is Dr. Høirup’s description — full of understanding and insight — of F. L. Grundtvig’s childhood and youth, his literary work in America, partly as a poet for the Danish settlers in “the country where the nations gather”, partly as editor and publisher of »Sangbog for det danske Folk i Amerika« (“Songbook for the Danish people in America”) — and finally as a theological author of treatises and studies of the Fathers of the Church. An enormous amount of work lies behind this well-informed and sympathetic biography — work based on both printed and unprinted sources. Dr. Høirup has had good help from many sides, not least from people who are still alive and who knew Frederik Lange Grundtvig and his work in America, especially his daughter, Mrs. Marie Lorange, Oslo. Of particular importance for research into N. F. S. Grundtvig’s life are the first chapters of the book, which paint a moving picture of the old father’s love for his little motherless son, and, at some decisive points, increase our knowledge concerning N. F. S. Grundtvig’s latest years. Frederik Lange Grundtvig’s life was tragic in many respects, because, in filial piety, he felt himself bound to his great father’s work and ideas and tried to preserve them and to realise them in practice in a land where the climate of thought was unfavourable to them — and in a period which was characterised by material progress more than by spiritual growth. But his destinity assumed dimensions which were worthy of the name which laid him under corresponding obligations, and it was not chance, but his own deeds and behaviour, which gave greatness to his all too short life
Spironolactone: diuretic or disease‐modifying drug in heart failure with preserved ejection fraction?
No full textThis article refers to 'Diuretic and renal effects of spirono-lactone and heart failure hospitalizations: a TOPCAT Americas analysis' by A.P. Kalogeropoulos et al., published in this issue on pages 1600-1610. With monthly costs of approximately US$12 in the USA and €5 in Europe, spironolactone is by a landslide the most cost-effective drug in the management of heart failure (HF) with reduced ejection fraction (HFrEF). In the Randomized Aldactone Evaluation Study (RALES), the treatment of 10 patients with HFrEF in New York Heart Association functional class III or IV saved one life after 2 years, 1 a number that still looks favourable in comparison with any other HF drug. The story is more nuanced in HF with preserved ejection fraction (HFpEF), but given the high number of treatment strategies that have failed over the past 15 years, the results of spironolactone in the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) trial remain among the best we have to offer our patients. In the TOPCAT trial, spironolactone use was associated with a non-significant 10% lower relative risk for all-cause mortality after 3.3 years, and a borderline significant 17% relative risk reduction for HF readmission was observed. 2 However, the primary endpoint of the trial, which combined both individual endpoints together with aborted cardiac arrest, was not statistically significant. Post hoc analyses of the TOPCAT trial identified significant regional differences in patient profiles, event rates and compliance with the study medication, demonstrating that the trial would have been positive if it had been limited to the subpopulation recruited in America or with objective evidence for HFpEF under the form of elevated natriuretic peptide levels. These somewhat ambiguous results make it even more important to understand how spironolactone exerts its beneficial effects in HF. Spironolactone is a prodrug that is rapidly metabolized in its major active metabolites with a long half-life (t 1/2): 7α-thiomethylspironolactone (t 1/2 = 13.8 h) and canrenone The opinions expressed in this article are not necessarily those of the Editors of the European Journal of Heart Failure or of the European Society of Cardiology.F.H.V. is supported by a Fellowship of the Belgian American Educational Foundation (B.A.E.F.) and by the Special Research Fund (BOF) of Hasselt University (BOF19PD04). Conflict of interest: none declared.Verbrugge, FH (corresponding author), Hasselt Univ, Fac Med & Life Sci, Biomed Res Inst, Campus Diepenbeek,Agoralaan Gebouw D, B-3590 Diepenbeek, Belgium.
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