2,734 research outputs found
The role of Plasmodium falciparum var genes in malaria in pregnancy
Sequestration of Plasmodium falciparum-infected erythrocytes in the placenta is responsible for many of the harmful effects of malaria during pregnancy. Sequestration occurs as a result of parasite adhesion molecules expressed on the surface of infected erythrocytes binding to host receptors in the placenta such as chondroitin sulphate A (CSA). Identification of the parasite ligand(s) responsible for placental adhesion could lead to the development of a vaccine to induce antibodies to prevent placental sequestration. Such a vaccine would reduce the maternal anaemia and infant deaths that are associated with malaria in pregnancy. Current research indicates that the parasite ligands mediating placental adhesion may be members of the P. falciparum variant surface antigen family PfEMP1, encoded by var genes. Two relatively well-conserved subfamilies of var genes have been implicated in placental adhesion, however, their role remains controversial. This review examines the evidence for and against the involvement of var genes in placental adhesion, and considers whether the most appropriate vaccine candidates have yet been identified
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Cooper, Stephen, Off-line. 12 works exhibited at Towner Art Gallery, Eastbourne and The Winchester Gallery
Introduction. Shakespeare: Overlapping Mediascapes in the Mind
Introduction to the issue 'Shakespeare in the Media. Old and New', Anglistica aion, 15.2, 2011, co-edited with co-author Katherine Rowe, discussing the place of Shakespeare in the media today and the 'state of the art' of Shakespeare studies on the topic
Letter from Sanford Rowe and W. W. Bass to Carl Hayden
Letter from Sanford Rowe and W. W. Bass to Carl Hayden requesting a re-examination on the proposed park boundaries as they are disadvantageous to current land owners surrounding the canyon
FIG. 1 in A preliminary account of the shallow-water echinoderms of Rodrigues, Mauritius, western Indian Ocean
FIG. 1. Sampling locations around Rodrigues.Published as part of Rowe, Frank & Richmond, Matthew, 2004, A preliminary account of the shallow-water echinoderms of Rodrigues, Mauritius, western Indian Ocean, pp. 3273-3314 in Journal of Natural History 38 (23) on page 3275, DOI: 10.1080/002229301695105, http://zenodo.org/record/525854
Data for Clarkson, Dwyer, Flecknell, Leach and Rowe, 'Handling method alters the hedonic value of reward in laboratory mice'
<p>Raw data files for the paper 'Handling method alters the hedonic value of reward in laboratory mice' by Jasmine M Clarkson, Dominic M Dwyer, Paul A Flecknell, Matthew C Leach and Candy Rowe.</p>This work was funded by a BBSRC DTP studentship grant (BB/J014516/1)
TEM Nanoparticle Measurement - ImageJ Macro
<p dir="ltr">This macro will automatically measure the size distribution of nanoparticles from TEM images using a custom trained Cellpose 2.0 model. Additional macro information is commented within the ImageJ Macro script.</p><p dir="ltr">The script was written on ImageJ Version 1.54f.<br>The following plugin is required:</p><ul><li>BIOP</li></ul><p dir="ltr">Additionally, a Cellpose python environment must be installed on the computer to make use of the Cellpose function through ImageJ.</p><p dir="ltr">The ImageJ Macro was written by Matthew Rowe ([email protected]) in collaboration with Kevin Nay ([email protected]).</p><p dir="ltr">https://github.com/mattyrowey/TEM_NP_Measurement</p>
Alcian Blue Goblet Cell Measurement - ImageJ Macro
<p dir="ltr">This macro will automatically measure the number of goblet cells from Alcian blue stained histology images using a custom trained Cellpose 2.0 model. Specific regions of intact mucosa were defined for analysis by importing predefined ROIs created in QuPath. Additional macro information is commented within the ImageJ Macro script.</p><p dir="ltr">The script was written on ImageJ Version 1.54f.<br>The following plugins are required:</p><ul><li>BIOP</li><li>ImageJTS Tools (installed from: https://github.com/petebankhead/imagejts-tools)</li></ul><p dir="ltr">Additionally, a Cellpose python environment must be installed on the computer to make use of the Cellpose function through ImageJ.</p><p dir="ltr">The ImageJ Macro was written by Matthew Rowe ([email protected]) in collaboration with Myat Noe Han ([email protected]).</p>
Reading World Upside Down: A Response to Matthew Sleeman and John Barclay
This essay discusses the argument of C. Kavin Rowe, World Upside Down: Reading Acts in the Graeco-Roman Age by engaging with criticisms and comments by Matthew Sleeman and John Barclay. The response accepts several key points, including the locatedness of the early believing communities, the place of the resurrection and ascension of Jesus, and the importance of heaven for the early Christians. The response also clarifies and defends the view of Christianity’s cultural subversiveness and political engagement implied in Acts, as well as the claim that ‘tension’ is the right interpretive vocabulary needed to grasp the Christian political stance(s) in Acts. </jats:p
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Making Sense of Microposts: Proceedings of the WWW'12 Workshop on 'Making Sense of Microposts', Lyon, France, April 16, 2012
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