95 research outputs found
Functional popliteal artery entrapment syndrome: use of ultrasound guided Botox injection as a non-surgical treatment option
No full textOBJECTIVE: To determine whether ultrasound-guided injection of botulinum toxin type A (BTX-A) is a viable alternative to surgical intervention for the treatment of functional popliteal artery entrapment syndrome (PAES). MATERIALS AND METHODS: Twenty-seven patients met diagnostic criteria confirming the presence of functional PAES and agreed to go ahead with ultrasound-guided BTX-A injection at the level of artery occlusion. Patients were assessed and treated at baseline and given the option for 'top-up' injections at 6 and 12 months. Patients provided subjective symptom reports at 6 and 12 months post intervention. RESULTS: No patients reported being worse off after the intervention; 59% of patients were categorized as having a good response (i.e., initial improvement that was maintained at 12 months), 22% a mixed response (i.e., an initial improvement that subsequently reduced over 12 months) and 19% a poor response (i.e., no difference) to treatment. CONCLUSIONS: Ultrasound-guided BTX-A injection represents a viable alternative to surgery in the treatment of functional PAES. Further study will help determine the optimum dose and frequency of injection to prevent recurrence of symptoms.No Full Tex
Youth and Adolescent Athlete Musculoskeletal Health: Dietary and Nutritional Strategies to Optimise Injury Prevention and Support Recovery
No full textBackground: Despite the well-documented benefits of exercise and sports participation, young athletes are particularly vulnerable to musculoskeletal injuries. This is especially true during periods of rapid growth, sports specialisation, and high training loads. While injuries are an inevitable aspect of sports participation, the risk can be minimised by promoting the development of strong, resilient tissues through proper nutrition and injury prevention strategies. Moreover, targeted nutrition strategies can accelerate recovery and rehabilitation, allowing for a quicker return to sports participation. Methods: This narrative review synthesises scientific evidence with practical insights to offer comprehensive dietary recommendations aimed at strengthening tissues and supporting the healing process during recovery and rehabilitation. The selection of all sources cited and synthesised in this narrative review were agreed upon by contributing author consensus, experts in sports nutrition (R.A., H.V., B.D.) and exercise and sports medicine (M.H.). Results: Key topics include factors that contribute to injury susceptibility, general dietary recommendations for growth and development, sports nutrition guidelines, and nutrition considerations during injury and rehabilitation. This review also addresses external factors that may lead to suboptimal nutrition, such as food literacy and eating disorders. Conclusions: By highlighting these factors, this article aims to equip coaches, nutritionists, dietitians, athletic trainers, physical therapists, parents/guardians, sporting organisations, and schools with essential knowledge to implement effective nutritional strategies for injury prevention, recovery, and rehabilitation, ultimately enhancing long-term health and athletic performance
The Effect Of Cannabidiol (CBD) On Exercise Physiology And Bioenergetics: A Randomised Controlled Pilot Trial
No full textEP-07 METABOLISM AND NUTRITION
The Effect Of Cannabidiol (CBD) On Exercise Physiology And Bioenergetics: A Randomised Controlled Pilot Trial
838
Sahinovic, Ayshe1; Irwin, Christopher2; Kevin, Richard C.1; Cox, Amanda J.2; Lau, Namson S.3; Desbrow, Ben2; Johnson, Nathan A.1; Sabag, Angelo4; Hislop, Matthew5; Haber, Paul S.1; McGregor, Iain S.1; McCartney, Danielle1
Author Information
Medicine & Science in Sports & Exercise: August 2021 - Volume 53 - Issue 8S - p 280
doi: 10.1249/01.mss.0000762344.41349.83
FREE
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PURPOSE: Cannabidiol (CBD) may exert physiological and psychological effects that benefit athletes (e.g. protect against neurological damage; reduce inflammation, anxiety and pain) (McCartney et al. 2020). This pilot study investigated the effects of CBD on physiological responses to exercise to determine its practical utility within the sporting context.
METHODS: On two occasions, nine endurance-trained males (VO2max: 57.4 ± 4.0 mL·min-1·kg-1) ran for 60 mins at a fixed, moderate-intensity (70% VO2max) (RUN 1) before completing an incremental run to exhaustion (RUN 2) on an indoor treadmill (21.4 ± 0.4 °C). Participants received an oral dose of CBD (300 mg) or placebo 1.5 hrs prior to exercise in a randomised, double-blind, crossover design. Respiratory gases were sampled continuously between 24-32, 37-45 and 50-58 mins of submaximal exercise; heart rate (HR), ratings of perceived exertion (RPEs), ratings of pleasure-displeasure, blood glucose (BG) and lactate (BL) concentrations were measured at 20-min intervals. Blood was drawn at baseline, pre- and post-RUN 1, post-RUN 2 and 1 hr post-RUN 2.
RESULTS: CBD tended to increase submaximal oxygen consumption (+24 ± 13 mL·min-1, p = 0.094). No differences in HR, RPE, BG, BL, or respiratory exchange ratio were observed during submaximal exercise (p’s > 0.10); VO2max (CBD: 3987 ± 462; Placebo: 3868 ± 577 mL·min-1; p = 0.121) and time to exhaustion (CBD: 1286 ± 150; Placebo: 1246 ± 197 sec; p = 0.204) were also similar during the incremental run. CBD tended to increase ratings of pleasure at 20- (p = 0.050) and 40-mins (p = 0.065) of submaximal exercise. Serum interleukin (IL)-6, IL-1β, tumor necrosis factor-α, lipopolysaccharide and myoglobin concentrations increased from baseline with exercise (i.e., post-RUN 1, post-RUN 2 and/or 1 hr post-RUN 2, p’s < 0.05); however, the change was too small to reliably evaluate the effect of CBD. Plasma CBD concentrations were 0 ± 0, 3 ± 2, 77 ± 18, 164 ± 35 and 99 ± 26 ng.mL-1 at each respective time point.
CONCLUSIONS: These preliminary findings suggest that CBD has potential to alter physiological responses during exercise. Further research involving a larger participant sample is required to confirm and better understand these effects. McCartney, D. Benson, M. Desbrow, B. Irwin, C. Suraev, A. McGregor, I. (2020) Sports Medicine Open 6, 27.No Full Tex
The Scandal Machine - BBC Radio 4, Archive on 4
No full textFrom backstage to front page, from printing press to digital age, criminologist Chris Greer traces the evolution of the scandal machine, revealing how scandals have changed - and how they might be changing us.
He's joined by a cast of scurrilous scandal mongers, investigative journalists and Westminster insiders, each with their own experiences of the inner workings of the scandal machine. Among them, Private Eye editor Ian Hislop, author and former parliamentary insider Michael Dobbs, screenwriter Amanda Coe and writer, broadcaster and former MP, Matthew Parris.
Social media has pushed the scandal machine into overdrive. Each day brings a deluge of fresh allegations against celebrities, politicians and institutions. But what exactly is a scandal and how did we get to this point?
Scandals are, in essence, morality tales. They bring the powerful to their knees, destroy reputations and end careers. Fear of being named and shamed in a front-page scandal is a powerful check on behaviour. But the shape and nature of scandal, and the way it is reported, is changing. Where scandals once mainly focused on the misconduct of individuals, today entire institutions are more commonly in the spotlight.
From Profumo to Weinstein and beyond, Chris Greer uses the archive to create a soundtrack of scandal.
A 7digital production for BBC Radio 4
Do electric crows fly over Adelaide?
No full textCatalogue of an exhibition held at SASA Gallery, Adelaide, 22 July-30 August 2013.
A collaborative project to construct an immersive neo-noir interior.Curators: Steve Kelly and Thomas Mical
External scholar, Michael Tawa
Artists/Designers: Andrew Butler, Disong Cheng, Katherine Donaldson, Mark Frost, Klaira Griffin, Peter Hilhorst, Kirrin Hembury, Todd Hislop, Tom Hocking, Shane Haddy, Patrick Holmes, Calum Hurley, Henry Jarvis, Margrethe Johannsen, Andre Lawrence, Jordon Leeflang, Michael Marner, Michael Majchrzak, Carly Mewett, Sarah Miller, Tessa Parry, Despina Pipikos, Jenna Schina, Jordon Schumacher, Morgan Thomson, Pedro Torres, Jessica Ware, Samuel Wiechula, Jack Wilde, Taylor Wiley, Karishma Wilson, Michael Wong.
Includes bibliographical references
Popliteal artery entrapment in a classical ballet dancer: successful conservative management
No full textHope is Round and Leather: Football Unifies a Strife-Torn Haiti
No full textIn lieu of an abstract, below is the first paragraph of the paper.
In strife-torn Caribbean nations such as Haiti, hope is hard to come by. Poverty and political conflicts throughout its history too often overshadow the islands\u27 stunning beauty and color. In these warm-climate islands that cry out for structure, only sport responds. In the Caribbean, the calendar year isn\u27t split by the season\u27s winter, spring, fall and summer, but into cricket season and football season (Hislop qtd. in Ferguson vii). Football, the proper and logical term for what America calls soccer, provides an opportunity that is often sought for, but rarely found. While cricket plays its part in the Caribbean, football as a unifying force is a commonality shared all over the world, capable of helping the most troubled areas. In this group of Caribbean nations that is divided no more geography than by political-strife and poverty, football provides hope, unifies the people and nations, and offers cultural pride as shown through Haiti as a lens
Lessons from CRISPR: Establishing an Ethical Framework for Emerging Neurological Devices
No full textabstract: The avalanche of ongoing bioscience research has resulted in an unprecedented range of opportunities for the creation of new medical diagnostics and therapies. As the potential to develop treatments for the human body expands, the ability to control, modify, and interfere with abstract parts of an individual's self increases. While basic components of the self - such as the mind, consciousness, and personality - can presently only be altered by natural processes and diseases, current and emerging technologies that can cause changes in the self are in development. It is likely that as understanding of the brain and mind increases, scientists and engineers will be develop the ability to alter the mind and consciousness in profound new ways. Such a paradigm shift will be fraught with ethical concerns, and if those concerns are not handled in an appropriate manner, there is significant potential for harm. This potential for causing harm is not without precedent. Genome editing technology is an area of research which deals with an element of the fundamental self. In recent years, advancements in genome editing technology in the form of the CRISPR/Cas9 system have caused alarm and debate within scientific communities concerning the ethicalness of its use and application. Using lessons learned from the ways in which the CRISPR technology has been beneficially used, an ethical framework might be developed in order to guide the development of emerging neurotechnology. Early implementation of a framework such as the one herein proposed could guide research that is already being conducted. There is still time to influence the way that neurological device research is conducted, and it is duty of ethical scientists in this field to understand and correct these problems clearly and quickly so as to prevent harm. An ethical framework that is consistent with current ethical standards and understandings might be created by reviewing the history and development of CRISPR
DYNAMIC TESTING OF INTERNAL COMBUSTION ENGINES
No full textPhDThe automated testing of internal combustion engines is a field
of considerable importance. This thesis describes a novel area in
the form of dynamic testing. The investigation represents an original
approach to the problem with which the author believes he has developed
a new concept in engine testing.
The resulting information, combined with an appreciation of the
latest developments in automation equipment technology, has lead to a
review of the requirements of a generalised engine test system together
with an outline of the way in which it could be implemented.
The automated engine test beds used during the work are described.
The conventional methods of testing internal combustion engines are reviewed
and a generalised approach to automating them proposed. This
then leads to the suggestion of a new method using dynamic testing techniques
specially evolved in the course of the work. On the basis of
this the implementation of a dynamic full-load power curve as a replacement
for its steady state equivalent was pursued.
The second major use of dynamic techniques is for exhaust emission
cycles. Both dynamic (USEPA Smoke Cycle) and steady-state (USEPA 13
Mode Cycle) cycles were performed. In the case of the former, outer
digital loop techniques were used to improve control response.
In performing the above work, use was made of both analog and
digital simulation techniques for development purposes. This work was
also extended by the development of a simulation of a material handling
system to enable the control and optimisation of a production test
facility to be studied. The testing methods associated with automated
fault diagnosis are also analysed.
On the basis of the above work an engine test system task analysis
was generated and this new concept used to plan a microprocessor
based engine test automation scheme
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