83 research outputs found

    Thermoresponsive Polymer Micropatterns Fabricated by Dip-Pen Nanolithography for a Highly Controllable Substrate with Potential Cellular Applications

    No full text
    We report a novel approach for patterning thermoresponsive hydrogels based on N,N-diethylacrylamide (DEAAm) and bifunctional Jeffamine ED-600 by dip-pen nanolithography (DPN). The direct writing of micron-sized thermoresponsive polymer spots was achieved with efficient control over feature size. A Jeffamine-based ink prepared through the combination of organic polymers, such as DEAAm, in an inorganic silica network was used to print thermosensitive arrays on a thiol-silanized silicon oxide substrate. The use of a Jeffamine hydrogel, acting as a carrier matrix, allowed a reduction in the evaporation of ink molecules with high volatility, such as DEAAm, and facilitated the transfer of ink from tip to substrate. The thermoresponsive behavior of polymer arrays which swell/deswell in aqueous solution in response to a change in temperature was successfully characterized by atomic force microscopy (AFM) and Raman spectroscopy: a thermally induced change in height and hydration state was observed, respectively. Finally, we demonstrate that cells can adhere to and interact with these dynamic features and exhibit a change in behavior when cultured on the substrates above and below the transition temperature of the Jeffamine/DEAAm thermoresponsive hydrogels. This demonstrates the potential of these micropatterned hydrogels to act as a controllable surface for cell growth

    Perceptions of universally designed adventure education in high school physical education

    No full text
    The purpose of this study was to investigate the effects of a universally designed adventure education (UDAE) program on students of varying ability levels. Five data collection techniques were employed to gain a rich understanding of the long term benefits of students with disabilities (SWD) and their nondisabled peers participating in a high school UDAE program. Data collection included semi-structured formal interviews, informal follow up interviews, observations, document analysis, and narrative descriptions. Participants included alumni of a UDAE program, parents of SWD in the program, and faculty members of a school district who initiated or supported the program. Themes developed included Generalization of Teachable Moments; Sense of Community; and Changing Life Perspectives. Findings depicted long-term engagement involving physical activity, special education, adapted physical education, and adventure education/outdoor pursuits amongst multiple populations. In conclusion, participation in UDAE programming during high school physical education can enhance positive feelings between individuals of varying populations that transition into life after graduation

    Faulds, Andrew Matthew William, (1 March 1923–31 May 2000)

    No full text

    Care of the critically ill patient

    No full text

    Overcoming Geographical Obstacles: The Use Of Skype In A Graduate-Level Social Media And Marketing Course

    No full text
    This paper presents the results of a three-year research and teaching effort that focused on measuring the perceived effectiveness of Skype as a delivery platform for presentations made to students enrolled in a Professional MBA program by nationally acclaimed authors working in the area of social media. The research also investigated the authors ’ acceptance of Skype as a platform for delivering remote presentations to college audiences. The results indicated that both students and authors strongly supported the use of Skype as a presentation platform. The author presentations greatly enhanced the learning environment and contributed to achieving several specific course objectives

    Mary Benson : the problem of defining the "self".

    No full text
    Thesis (M.A.)-University of Natal, Durban, 1991.This study investigates the problem of defining Mary Benson as a person and a writer. Her writing spans a range of generic classifications - biography, history, plays, a novel and an autobiography. Yet, all are centred on her preoccupation with the struggle for freedom in South Africa. All reveal, moreover, a great deal about Benson's own values and commitment, prompting us to question the validity, in her case, of such strict generic categories as useful defining properties in her literary career. Starting with her most recent publication, the autobiography A Far Cry. I shall look at the way she presents herself in a traditionally introspective genre. It soon becomes apparent that Benson views herself within a perspective of South African social reality, and that her sense of self is inextricably linked to her political involvement. Her personal needs and desires, to a large extent, remain unobtrusive as she foregrounds her public interactions and her concern with humanitarian and racial issues. A study of Benson, therefore, needs to address a selection of her work in an attempt to fully appreciate her sense of her own identity. In consequence, I go on to discuss her biography Nelson Mandela and her novel At the Still Point. .Both works confirm the portrait in A Far Cry of Benson as a responsible South African who has selflessly and consistently devoted herself to her role as a witness of racial oppression in South Africa. In her biography, Nelson Mandela, for example, the ANC leader emerges as an exemplary figure in the public world while his values and ideals are allowed to parallel Benson's own 'autobiographical' ideals. In At the Still Point, Anne Dawson, Benson's fictional protagonist, I shall argue, gives her author the opportunity to express her own feelings about private life in relation to sociopolitical action. These 'personal ' feelings seem to be avoided in the more direct opportunities of the autobiographical form. In exploring Benson's sense of self, therefore, this study suggests that for Benson 'commitment' overrides her sense of herself as a literary figure, and that this has consequences for the weight we give to content and form in the reading of her work. My conclusion is that we are looking not so much at the challenges of genre as at a large autobiographical project, in which the 'self is defined substantially in its meetings with other people in political circumstance

    Gastrointestinal physiology

    No full text

    The Immunophilin-Like Protein XAP2 Is a Negative Regulator of Estrogen Signaling through Interaction with Estrogen Receptor alpha

    No full text
    This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
    corecore