114 research outputs found

    Hot tub lung machine

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    Hot tub lung (HTL) is a pulmonary disease where a hypersensitivity pneumonitis is caused by exposure and inhalation of aerosolized non‐tuberculous mycobacteria (NTM) traditionally from hot water steam. HTL can affect both immunocompromised and healthy individuals, and diagnosis is dependent on high clinical suspicion in conjunction with high‐resolution computed tomography (HRCT) and microbiological evidence. We present, to our knowledge, the only case of HTL occurring from an indoor swimming pool affecting five members of a family, in which one member was not a resident of the household.Full Tex

    Preoperative Imaging Continues to Lower Negative Appendicectomy Rates (NAR)-A Retrospective Analysis of a Tertiary Health Service in Australia

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    Aim: To analyze the Negative Appendicectomy Rate (NAR) in a single tertiary health service, compare it to published data and analyze the impact of pre-operative imaging in acute appendicitis. Methods: A retrospective cohort study of a single health service was performed for a single year. Search terms included ‘diagnostic laparoscopy’ and ‘appendicectomy’ (both laparoscopic and open). Demographic data was extracted. The primary outcome was NAR. Secondary outcomes included tumour incidence and imaging modality accuracy as defined by NAR. Data was excluded if there was no histopathological report available. Results: A total of 820 cases were identified, with 736 operations being performed for suspected appendicitis. A total of 633 booked laparoscopic appendicectomies were included for analysis, yielding an NAR of 11.2%. Overall tumour incidence was calculated at 1.5%. No preoperative imaging, or cases which utilized ultrasound as the only imaging modality, produced NARs of 19.3% and 17.4% respectively. Use of Computed Tomography (CT) in males under 40 was associated with lower NAR (3.0%, p=0.01) but no statistical difference was found between no imaging and ultrasound-only in this age group. Ultrasound-only was better than no imaging for females of all ages (p0.05). Preoperative CT was overall statistically significant at correctly identifying appendicitis (OR 2.80, p<0.001), giving an NAR of 7.1%. Conclusion: This study’s NAR is better than accepted rates, however, is still high when compared internationally. There is great potential in the use of preoperative imaging to further guide correct diagnosis and operative patient selection.Full Tex

    Benign paroxysmal positional vertigo in a young child

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    A girl in her early childhood presented to a regional otolaryngology outpatient clinic with classic signs of benign paroxysmal positional vertigo (BPPV). She reported episodic dizziness when rolling in a supine position. She did not convey any other associated audiovestibular symptoms. A bedside Dix-Hallpike test confirmed geotropic rotational nystagmus indicative of lateral canal BPPV. Due to her young age, limited communicative abilities and concerns for more sinister underlying pathology, a complete neurological examination, MRI and pure tone audiometry were performed. After two sessions of Epley’s manoeuvre, she was symptom-free. At her 3-month follow-up, the patient denied any recurrent episodes of vertigo.No Full Tex

    [Photograph 2012.201.B0240.0345]

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    Photograph taken for a story in the Oklahoma Times newspaper. Caption: "Helen Corbitt, noted cookbook author is visiting Oklahoma City.

    Fistulating diverticular disease masquerading as a peri-anal abscess: a laparoscopic approach to management

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    We present a rare case of complicated sigmoid diverticulitis presenting as a peri-anal abscess from an extra-sphincteric fistulous tract. This presentation of a colocutaneous peri-anal abscess is extremely rare, with only a handful of cases described in the literature. Most are managed with an open sigmoid colectomy, however, this case was successfully managed laparoscopically. It highlights the need to consider extra-levator causes of peri-anal abscess, such as pelvic sepsis causing fistulating disease, and to consider early magnetic resonance imaging if there is clinical suspicion of underlying pathology. It also demonstrates that a safe and potentially less morbid outcome is possible via laparoscopic approach when compared to traditional open surgical approach.Full Tex

    Fort Worth Symphony Orchestra Cooking School

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    Guests at the Fort Worth Symphony Orchestra Cooking School will sample foods prepared by Helen Corbitt, author of the cookbook being studied by Mrs. Harold B. Eudaly Jr., one of the hostesses. Also performing hostess duties will be Mrs. F. E. Altaras, who is taste-testing the casserole offered by Mrs. Robert C. Matteson. Fort Worth Star-Telegram Morning October 17, 1965.https://mavmatrix.uta.edu/specialcollections_startelegram1960s/2982/thumbnail.jp

    A systematic review of cytokines in chronic fatigue syndrome/myalgic encephalomyelitis/systemic exertion intolerance disease (CFS/ME/SEID)

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    Background: Cytokines in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis/Systemic Exertion Intolerance Disease (CFS/ME/SEID) patients compared with healthy controls have been extensively studied. However, the evidence regarding whether a baseline difference between CFS/ME/SEID patients and the normal population remains unclear. The aim of this study was to conduct a systematic review of the literature regarding cytokines in CFS/ME/SEID and whether there is a significant difference in cytokine levels between this patient group and the normal population. Methods: Pubmed, Scopus, Medline (EBSCOHost), and EMBASE databases were searched to source relevant studies for CFS/ME/SEID. The review included any studies examining cytokines in CFS/ME/SEID patients compared with healthy controls. Results of the literature search were summarised according to aspects of their study design and outcome measures, namely, cytokines. Quality assessment was also completed to summarise the level of evidence available. Results: A total of 16,702 publications were returned using our search terms. After screening of papers according to our inclusion and exclusion criteria, 15 studies were included in the review. All the included studies were observational case control studies. Ten of the studies identified measured serum cytokines in CFS/ME/SEID patients, and four measured cytokines in other physiological fluids of CFS/ME/SEID patients. The overall quality assessment revealed most papers included in this systematic review to be consistent. Conclusions: Despite the availability of moderate quality studies, the findings of this review are inconclusive as to whether cytokines play any definitive role in CFS/ME/SEID, and consequently, they would not serve as reliable biomarkers. Therefore, in light of these results, it is recommended that further efforts toward a diagnostic test and treatment for CFS/ME/SEID continue to be developed in a range of research fields.Full Tex

    ‐19 pandemic: a single hospital experience

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    BACKGROUND: Surgical departments have been dramatically impacted by the novel coronavirus 19 (COVID‐19) pandemic, with the cancellation of elective cases and changes to the provision of emergency surgical care. The aim of this study was to determine whether structural changes made within our facility's surgical department during COVID‐19 altered National Emergency Access Target (NEAT) times and impacted on patient outcomes. METHODS: Emergency surgical cases over a 4‐month time period were retrospectively collected and statistically analysed, divided into pre‐ and mid‐COVID‐19 pandemic. RESULTS: Baseline characteristics between the groups were comparable. There was a significant increase in consultant presence in theatre in the COVID group. There were also statistically significant reductions in NEAT times at each timepoint, although these did not meet national guidelines. There was no change in emergency surgical workload, complication rate or mortality rates within 30 days. CONCLUSION: Any significant change to services requires a coordinated hospital‐wide approach, not just from a single department, and clinicians must continue to be wary of benchmarked times as the overall feasibility and safety of NEAT times has also been highlighted again

    Investigation of FAA Research and Regulation of Insulin-Treated Diabetic Pilots

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    abstract: The field of study that this topic is derived from constitutes both federal aviation regulation as well as medical and biological sciences. The compelling idea of this thesis is an in depth investigation of the Federal Aviation Administration's (FAA) regulation and data collection throughout time regarding pilots with Insulin Treated Diabetes Mellitus (ITDM). When in comparison to the continuous evolution of diabetic research and endocrinology in all parts of the world, the regulations regarding this group of pilots seems displaced. This paper explores a chronological order of FAA research and regulations that were conducted on diabetic pilots stemming from 1959 - present. The findings seem to convey that the field of aviation is laden with inconsistencies and misplaced conclusions regarding regulation of insulin-treated diabetic pilots. This paper reflects on the impact of these regulations on this group of pilots from both a biological and medical standpoint as well as from an aviation point of view. In light of advanced medical knowledge, the paper explores what regulations regarding ITDM are in other countries and how FAA regulation should be refined and altered to realign with present day medical knowledge in the United States. This research was conducted to compare the sequential endocrinologic knowledge conducted and the subsequent regulatory actions
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