1,398 research outputs found

    Postcard from Mrs. D.L. Cooke to Sam Tanaka, August 1943

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    Postcard from Mrs. D.L. Cooke to Sam Tanaka in the Jerome incarceration camp including a greeting and update from Cooke.The Japanese American Archival Collection documents the people, places, and daily life of Japanese Americans, primarily those who lived in the once thriving community of pre-war Florin in the Sacramento region, as well as the conditions in American incarceration camps during World War II. The approximately 7,000 original items include personal and official letters, photographs, diaries, arts and crafts, newsletters, textiles, camps artifacts, yearbooks and other publications

    Size heterogeneity, phosphorylation and transmembrane organisation of desmosomal glycoproteins 2 and 3 (desmocollins) in MDCK cells

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    Metabolic labelling with [35S]methionine and immunoprecipitation with specific antibodies to bovine desmosomal glycoproteins 2 and 3 (dg2 and dg3: desmocollins) reveals a triplet of polypeptides of Mr 115,000, 107,000 and 104,000 in MDCK cells. Tunicamycin treatment shows that this heterogeneity does not arise through differential N-linked glycosylation. Under conditions in which cells are actively forming desmosomes, the largest polypeptide, dg2, becomes phosphorylated on serine, but the two smaller polypeptides, dg3a and 3b, do not. Controlled trypsinisation of intact cells yields three membrane-protected fragments (Mr 28,000, 24,000 and 23,000) derived from these glycoproteins. The largest of these fragments is phosphorylated but the two smaller fragments are not. A monoclonal antibody to bovine dg2 and dg3 stains MDCK cells cytoplasmically. In immunoblotting of MDCK cells the monoclonal antibody recognises dg2 strongly and shows a weaker reaction with a band of lower Mr corresponding to dg3a. It also recognises the immunoprecipitated 28,000 Mr fragment from trypsinised cells and a smaller fragment of 24,000 Mr. The simplest interpretation of these data is that all three glycoproteins have a transmembrane configuration with a single membrane-spanning domain, and show heterogeneity of size and phosphorylation in their cytoplasmic domains. The data are discussed in relation to the known structures of some cell adhesion molecules. Questions about the relative roles and distributions of the different polypeptides in desmosomal organisation are raised. <br/

    Alpha, Mu and Pi Class Glutathione S-Transferases in Human Synovium and Cultured Synovial Fibroblasts: Effects of Interleukin-1α, Hydrogen Peroxide and Inhibition of Eicosanoid Synthesis

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    We describe expression of alpha, mu and pi class glutathione S-transferases (GST) and, CuZn- and Mn superoxide dismutase (SOD) in human synovium and cultured synovial fibroblasts. Immunohistochemical and immunoblotting studies showed synovium and cultured cells expressed pi GST and both isoforms of SOD. Cellular localisation was largely perinuclear. No expression of alpha or mu GST was detected even though polymerase chain reaction analysis showed 4/6 subjects had positive genotypes at the polymorphic, mu class GSTM1 locus. Incubation of cultured synovial fibroblasts with H2O2, IL-1α and the cyclooxygenase and lipoxygenase inhibitor, Tenidap, did not induce expression of alpha, mu or pi GST though treatment with IL-1α caused a marked increase in the expression of Mn SOD

    Specialty farming in Idaho: Selecting a site

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    Bulletin no. 744 Moscow, Idaho :University of Idaho, College of Agriculture, Cooperative Extension System, 1992-10-01. Author(s): Barney, D.L.; Finnerty, T.L.; Mancuso, C.J

    Cross-Cultural Meta-Analyses

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    In the enormous collection of cross-cultural data that have been published during the last few decades it is difficult to perceive patterns. There is a clear need for systematizing the vast amount of cross-cultural studies and for developing models that explain cross-cultural differences in psychology. Two methods of cross-cultural meta-analysis can be distinguished. First, the instrument-based method of comparing data for one instrument across countries is suitable for instruments which have been administered in many countries. Second, a domain-based meta-analysis used a thematic domain from which culture-comparative studies are sampled instead of one specific instrument or method

    La durata della somministrazione a termine

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    Il saggio esamina le innovazioni introdotte nella somministrazione a tempo determinato dal d.l. n. 34/2014, conv. l. 78/2014. Si rileva come la nuova legge, accomuna contratto di lavoro a termine e contratto di somministrazione a tempo determinato e si evidenziano le incertezze della nuova normativa determinate dalla commistione tra disciplina di somministrazione a termine e disciplina di contratto a termine.The essay examines the innovations introduced in the fixed term labour-only subcontracting by d.l. n. 34/2014, conv. l. 78/2014. The Author remarks that the Act, unites fixed term employment contract and fixed term subcontracting. The uncertainties of the new regulation determined by the blending of the regulation of fixed term employment contract and fixed term subcontracting are also highlighted

    A large-scale biomass bulk terminal

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    This research explores the possibility of a large-scale bulk terminal in West Europe dedicated to handle solid and liquid biomass materials. Various issues regarding the conceptual design of such a terminal have been investigated and demonstrated in this research: the potential biomass materials that will be the major international trade flows in the future, the characteristics of these potential biomass materials, the interaction between the material properties and terminal equipment, the perspective from terminal logistic process, and the terminal configuration. To this day no such a terminal exists yet. Therefore, the results from this research are a first step that will help the future development of such a terminal.Marine and Transport TechnologyMechanical, Maritime and Materials Engineerin

    La raffigurazione dell'Arcangelo Michele nella monetazione medievale

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    Questo articolo nasce dall’unione delle relazioni tenute dall’autore nel corso dei convegni “Langobardorum Nummorum Doctrina” (2018) e “In Sanctorum Nummis Effigies” (2019). Dopo un’attenta ricerca viene mostrato il percorso dell’iconografia micaelica nella monetazione medievale e il suo cammino attraverso l’Europa. L’effige del santo raffigurata in primis dai Gepidi e poi da Longobardi e Bizantini, si diffonderà in tutta l’Europa medievale, dal Regno di Sicilia fino alla Danimarca. Il lavoro, frutto non solo di una ricerca numismatica, ma anche storica e artistica, vuole essere un punto di partenza di uno studio più complesso che l’autore sta compiendo sulla raffigurazione del santo nelle monete medievali.This article was born from the union of the reports given by the author during the conferences “Langobardorum Nummorum Doctrina” (2018) and “In Sanctorum Nummis Effigies” (2019). After careful research, the path of Michaelic iconography in medieval coinage and its journey through Europe is demonstrated. The effigy of the saint depicted primarily by the Gepids, and then by the Lombards and the Byzantines, spread throughout medieval Europe, from the Kingdom of Sicily to Denmark. This work, the result not only of numismatic but also of historical and artistic research, is intended to be a starting point for a more complex study that the author is carrying out on the depiction of the saint in medieval coins
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