1,720,999 research outputs found

    The Prevalence of Termination Variations of the Basilar Artery:A Systematic Review and Meta-Analysis

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    Purpose: Understanding the vascular anatomical variations of the termination pattern of the basilar artery is crucial for both neurosurgical and interventional radiological procedures. Recent evidence indicates that variant bifurcation patterns of the basilar artery, differing from the classical textbook descrip- tion, are increasingly encountered. This study aims to provide a comprehensive summary of the prevalence of termination anomalies related to the basilar artery.Methods: This systematic review included human cadaveric and imaging studies on basilar artery termination patterns. PubMed, Ovid MEDLINE, and Scopus databases were system- atically searched in accordance with PRISMA guidelines, us- ing the terms “(basilar OR vertebrobasilar OR (posterior AND circulation)) AND (anatomy OR termination OR trifurcation OR quadfurcation OR pentafurcation OR hexafurcation OR nonfurcation OR variation OR variant)”. A meta-analysis of proportions was conducted to assess the prevalence of each variation using a random intercept logistic regression model, following logit transformation of the proportions.Results: From 845 initial hits, 4 articles were eligible for the quantitative analysis. The estimated pooled proportions of bifurcation, trifurcation, quadfurcation, pentafurcation, hexa- furcation, and non-furcation in the artery, under the random effects model, were 62.22% (95%CI [34.48%; 83.75%]), 6.08% (95%CI [2.60%; 13.58%]), 5.27% (95%CI [2.17%; 12.27%]),2.06% (95%CI [0.96%; 4.35%]), 0.49% (95%CI [0.08%; 2.90%]), and 0.10% (95%CI [0.0%; 17.07%]), respectively. Heterogeneity analysis revealed significant variability among the studies (I2 up to 93.6%, p&lt;0.0001).Conclusion: More than one-third of basilar artery termi- nations exhibit anatomical variations other than bifurcation. Trifurcation and quadfurcation are the most commonly re- ported variations, each accounting for over 5% of cases. These variations might carry significant implications for regional neurosurgical and interventional radiological procedures.<br/

    The Prevalence of Termination Variations of the Basilar Artery:A Systematic Review and Meta-Analysis

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    Purpose: Understanding the vascular anatomical variations of the termination pattern of the basilar artery is crucial for both neurosurgical and interventional radiological procedures. Recent evidence indicates that variant bifurcation patterns of the basilar artery, differing from the classical textbook descrip- tion, are increasingly encountered. This study aims to provide a comprehensive summary of the prevalence of termination anomalies related to the basilar artery.Methods: This systematic review included human cadaveric and imaging studies on basilar artery termination patterns. PubMed, Ovid MEDLINE, and Scopus databases were system- atically searched in accordance with PRISMA guidelines, us- ing the terms “(basilar OR vertebrobasilar OR (posterior AND circulation)) AND (anatomy OR termination OR trifurcation OR quadfurcation OR pentafurcation OR hexafurcation OR nonfurcation OR variation OR variant)”. A meta-analysis of proportions was conducted to assess the prevalence of each variation using a random intercept logistic regression model, following logit transformation of the proportions.Results: From 845 initial hits, 4 articles were eligible for the quantitative analysis. The estimated pooled proportions of bifurcation, trifurcation, quadfurcation, pentafurcation, hexa- furcation, and non-furcation in the artery, under the random effects model, were 62.22% (95%CI [34.48%; 83.75%]), 6.08% (95%CI [2.60%; 13.58%]), 5.27% (95%CI [2.17%; 12.27%]),2.06% (95%CI [0.96%; 4.35%]), 0.49% (95%CI [0.08%; 2.90%]), and 0.10% (95%CI [0.0%; 17.07%]), respectively. Heterogeneity analysis revealed significant variability among the studies (I2 up to 93.6%, p&lt;0.0001).Conclusion: More than one-third of basilar artery termi- nations exhibit anatomical variations other than bifurcation. Trifurcation and quadfurcation are the most commonly re- ported variations, each accounting for over 5% of cases. These variations might carry significant implications for regional neurosurgical and interventional radiological procedures.<br/

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    In Situ Monitoring of Transiently Formed Molecular Chaperone Assemblies in Bacteria, Yeast, and Human Cells.

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    J-domain proteins (JDPs) form the largest and the most diverse co-chaperone family in eukaryotic cells. Recent findings show that specific members of the JDP family could form transient heterocomplexes in eukaryotes to fine-tune substrate selection for the 70 kDa heat shock protein (Hsp70) chaperone-based protein disaggregases. The JDP complexes target acute/chronic stress induced aggregated proteins and presumably help assemble the disaggregases by recruiting multiple Hsp70s to the surface of protein aggregates. The extent of the protein quality control (PQC) network formed by these physically interacting JDPs remains largely uncharacterized in vivo. Here, we describe a microscopy-based in situ protein interaction assay named the proximity ligation assay (PLA), which is able to robustly capture these transiently formed chaperone complexes in distinct cellular compartments of eukaryotic cells. Our work expands the employment of PLA from human cells to yeast (Saccharomyces cerevisiae) and bacteria (Escherichia coli), thus rendering an important tool to monitor the dynamics of transiently formed protein assemblies in both prokaryotic and eukaryotic cells

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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