1,721,007 research outputs found
Cerebral choline acetyltransferase and acetylcholinesterase activities in a Sanfilippo syndrome, in a myoclonic epilepsy and in various zones of the human newborn brain
No full textAcetylcholinesterase (AChE) and choline acetyltransferase (ChAT) activities were measured in the brain of two cases: a Sanfilippo syndrome and a myoclonic epilepsy. Both AChE and ChAT activities were decreased in the Sanfilippo mucopolysaccharidosis, while only ChAT was decreased in the myoclonic epilepsy. These findings can be related to the epileptic phenomena and/or to the degenerative processes which take place in the cerebral cholinergic pathways, due to the dismetabolic diseases. ChAT and AChE activities were also analyzed in different brain regions of an 8 day old newborn infant. The highest activity was not found in the basal nuclei, but in the cerebellum which is known, in the adult, to contain very little AChE and ChAT activities
Receptor-mediated increases in phosphatidylinositol turnover in a human neuroblastoma cell line, LAN-2
No full textModulation of phospholipid synthesis by a muscarinic receptor agonist in a human neuroblastoma cell line, LAN-1.
No full textLa Risonanza Magnetica Funzionale nello studio dell’epilessia e del disturbo da attacchi di panico: stato dell’arte e prospettive future
No full textCholine acetyltransferase activity bound to synaptosomal plasma membranes as regulatory step in acetylcholine biosynthesis
No full text
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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