506 research outputs found
Viral Hemorrhagic Fevers(Emerging and re-emerging diseases,Symposium)
No full textAlthough there are no endogenous viruses which cause hemorrhagic fevers in Japan, we have been confronting the treat of invasion by the viruses. Among them, Marburg disease, Ebola hemorrhagic fever, Lassa fever, Crimea-Congo hemorrhagic fever are designated most dangerous disesases, and control measures of these viruses incuding the development of safe diagnistic methods should be uregently established in Japan
Lessons Learnt from (HIN1)2009 Influenza Pandemic for Preparedness Against Future Pandemics
No full text
The dual use research of concern issue on publications of H5N1 highly pathogenic avian influenza virus mutants with pandemic potential in humans
No full textMOLECULAR BASES OF SENDAI VIRUS PATHOGENICITY : HOST PROTEASES FOR PROTEOLYTIC ACTIVATION OF PROGENY VIRUSES AND VIRUS BUDDING DOMAIN AT THE PRIMARY INFECTION SITE
No full text国内における男性看護師のキャリア形成に影響する要因についての文献的研究
No full textThis study aims to examine influential factors for the career development of male nurses through the preceding study analyses. We conducted AND Search with “Male nurse” and “Career” by utilizing ICHUSHI (Bibliographic database) and CiNii (Citation Information by National institute of informatics) available on the Web, then targeted 22 papers in line with the study purpose. We also classified the targeted papers into 7 categories and 23 sub-categories after conducting qualitative/ inductive content analysis in terms of influential factors for the career development of male nurses. 3 categories indicate “Gender awareness”, “Family background” and “Relationship-building between nurses” as a distinctive category of male nurse. Particularly “Gender awareness” and “Family background” is influenced by social awareness of masculinity in the nursing profession. We also found that “Relationship-building between nurses” is a factor of male nurses relevant to a human relationship with female nurses or a majority group. Furthermore, “Factor for identity formation”, “Factor for continuous employment”, “With/without a desire for a strong rise intention”, and “Existence of role model” can be influential factors for the career development of nurses regardless of gender. In addition, “With/without a desire for a strong rise intention” was extracted as a unique research viewpoint. While this is possibly an influential factor for the career development of nurses regardless of gender, we considered that it would influence the consciousness such as advance to graduate school, promotion to specialized nurse or manager, and career advancement
Sodium gradient-dependent transport of magnesium in rat ventricular myocytes
No full textCytoplasmic concentration of Mg2+([Mg2+]i) was measured with a fluorescent indicator furaptra in ventricular myocytes enzymatically dissociated from rat hearts (25°C). To study Mg2+transport across the cell membrane, cells were treated with ionomycin in Ca2+-free (0.1 mM EGTA) and high-Mg2+(10 mM) conditions to facilitate passive Mg2+influx. Rate of rise of [Mg2+]idue to the net Mg2+influx was significantly smaller in the presence of 130 mM extracellular Na+than in its absence. We also tested the extracellular Na+dependence of the net Mg2+efflux from cells loaded with Mg2+. After [Mg2+]iwas raised by ionomycin and high Mg2+to the level 0.5–0.6 mM above the basal value (∼0.7 mM), washout of ionomycin and lowering extracellular [Mg2+] to 1.2 mM caused rapid decline of [Mg2+]iin the presence of 140 mM Na+. This net efflux of Mg2+was completely inhibited by withdrawal of extracellular Na+and was largely attenuated by imipramine, a known inhibitor of Na+/Mg2+exchange, with 50% inhibition at 79 μM. The relation between the rate of net Mg2+efflux and extracellular Na+concentration ([Na+]o) had a Hill coefficient of 2 and [Na+]oat half-maximal rate of 82 mM. These results demonstrate the presence of Na+gradient-dependent Mg2+transport, which is consistent with Na+/Mg2+exchange, in cardiac myocytes.</jats:p
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