79,960 research outputs found
The marriage of Philip of Habsburg and Mary Tudor and anti-Spanish sentiment in England : political economies and culture, 1553-1557.
No full textPhDThis thesis examines the early part of Mary I's reign, focusing on her marriage to
Philip of Habsburg and the marginalisation of their co-monarchy in Tudor historiography.
By looking at the diplomatic background and political opposition in England, I interrogate
the notion that anti-Spanish sentiment was a central cause of the Wyatt rebellion, arguing that
instead its aetiology lay in female sovereignty and the constitutional uncertainties produced
by it. Dynasticism tended to alienate power from familiar, local and territorial sources of
political authority. Infant mortality and the vicissitudes of the marriage market in this context
threatened discrete 'national' identities with an incipient imperialist internationalism. I analyse
in detail the marriage contract and 'Act declaring that the regal power of this realm is in the
Queen's Majesty', using them as evidence to show that anxieties about property rights were
not related to the repudiation of the Supremacy, repeal of Henrician legislation and return of
papal jurisdiction. The staging of the wedding harped on Philip's inferior status, inverting that
which the marriage ceremony rehearsed. The Castilian writing of England as a romance of
chivalry sublimated a sexual licence which repeated the fears played upon by exiled
polemicists that the kingdom had been transformed into the feminised subject of Spanish
male authority. Anti-Spanish propaganda did not reflect popular xenophobia. It was literate
and sophisticated, related to sectarian struggle and engaged with theories of justifiable
disobedience. Finally, I treat the joint royal London Entry and representations of Philip and
Mary welcoming his assumption of authority in relation to both England and his new quee
Fermionic T-duality and U-duality in type II supergravity
No full textPhDThis thesis deals with the two duality symmetries of N = 2 D = 10 supergravity
theories that are descendant from the full superstring theory: fermionic
T-duality and U-duality.
The fermionic T-duality transformation is applied to the D-brane and ppwave
solutions of type IIB supergravity. New supersymmetric solutions of complexi
ed supergravity are generated. We show that the pp-wave yields a purely
imaginary background after two dualities, undergoes a geometric transformation
after four dualities, and is self-dual after eight dualities.
Next we apply six bosonic and six fermionic T-dualities to the AdS4 CP3
background of type IIA supergravity, which is relevant to the current research
in the amplitude physics. This helps to elucidate the potential obstacles in
establishing the self-duality, and quite independently from that shows us that
fermionic T-dualities may be degenerate under some circumstances.
Finally, we make a step towards constructing a manifestly U-duality covariant
action for D = 10 supergravities by deriving the generalized metric for a
D1-brane. This is a single structure that treats brane wrapping coordinates on
the same footing as spacetime coordinates. It turns out that the generalized
metric of a D-string results from that of the fundamental string if one replaces
the spacetime metric with the open string metric. We also nd an antisymmetric
contribution to the generalized metric that can be interpreted as a noncommutativity
parameter
Sister Mary Joseph's Nodule at a University Teaching Hospital in Northwestern Tanzania: A Retrospective Review of 34 cases.
Get PDFSister Mary Joseph's nodule is a metastatic tumor deposit in the umbilicus and often represents advanced intra-abdominal malignancy with dismal prognosis. There is a paucity of published data on this subject in our setting. This study was conducted to describe the clinicopathological presentation and treatment outcome of this condition in our environment and highlight challenges associated with the care of these patients, and to proffer solutions for improved outcome. This was a retrospective study of histologically confirmed cases of Sister Mary Joseph's nodule seen at Bugando Medical Centre between March 2003 and February 2013. Data collected were analyzed using descriptive statistics. A total of 34 patients were enrolled in the study. Males outnumbered females by a ratio of 1.4:1. The vast majority of patients (70.6%) presented with large umbilical nodule > 2 cm in size. The stomach (41.1%) was the most common location of the primary tumor. Adenocarcinoma (88.2%) was the most frequent histopathological type. Most of the primary tumors (52.9%) were poorly differentiated. As the disease was advanced and metastatic in all patients, only palliative therapy was offered. Out of 34 patients, 11 patients died in the hospital giving a mortality rate of 32.4%. Patients were followed up for 24 months. At the end of the follow-up period, 14(60.9%) patients were lost to follow-up and the remaining 9 (39.1%) patients died. Patients survived for a median period of 28 weeks (range, 2 to 64 weeks). The nodule recurred in 6 (26.1%) patients after complete excision. Sister Mary Joseph's nodule of the umbilicus is not rare in our environment and often represents manifestation of a variety of advanced intra-abdominal malignancies. The majority of the patients present at a late stage and many with distant metastases. The patient's survival is very short leading to a poor outcome. Early detection of primary cancer at an early stage may improve the prognosis
The uniqueness of Mary Shelley's Frankenstein in the gothic literary tradition
Get PDFDissertação (mestrado) - Universidade Federal de Santa Catarina. Centro de Comunicação e ExpressãoA literatura gótica inglesa, cujo florescer abrangeu as últimas décadas do Século XVIII até a primeira metade do Século XIX, é geralmente alvo de um evidente menosprezo embora a grande aceitação por parte do público leitor da época. Provavelmente, algumas das razões para tal preconceito estejam relacionadas com as características um tanto quanto formulísticas do gênero bem como com os exageros ali contidos. Estes fatores, entre outros, talvez tenham ocasionado o descaso do público moderno para com a maioria das traduções góticas. Porém, o romance Frankenstein: ou o Moderno Prometeu (1818) da escritora inglesa Mary Shelley parece ter desafiado todo e qualquer preconceito quanto ao seu gênero literário e não apenas sobrevive ainda mas é, inclusive, considerado por muitos atualmente como um mito moderno. A longevidade desta obra sui generis poderia ter sido investigada sob vários ângulos diferentes e decidiu-se examiná-la sob a perspectiva do fato de Frankenstein pertencer ao gênero gótico. Para tanto fez-se imperativa a leitura de outras obras representantes do goticismo como forma de possibilitar uma análise contrastiva que pudesse apresentar as razões para a singularidade de Frankenstein dentro da literatura gótica. Em seguida realiza-se uma análise contrastiva entre Frankenstein e esses romances
Diary of Mary H. Linford, Book no. 10 from 10 February 1925 to 6 November 1927
No full textDiary of Mary Hooper (Blood) Linford, wife of Prof. James H. Linford, covering the period from 10 February 1925 to 6 November 192
Mary Clearman Blew
No full textIntroduction written by Joy Passanante about former U of I Creative Writing professor and award-winning author, Mary Clearman Blew, for an author reading at the Kenworthy Peforming Arts Centre on November 15, 2022
A study into the influence of amyloid-beta peptide oxidation on the rate of fibril formation, with a synthesis of 2-oxo-histidine
Get PDFThe Amyloid Cascade Hypothesis states that fibrillation of the amyloid beta (A~) peptide is the primary cause of Alzheimer's pathology. The trigger for the fibrillation is a subject of much debate, although it is clear, oxidative stress is a key feature of Alzheimer's aetiology. This thesis explores a possible role of oxidation of A~, in particular the effect of histidine and methionine side-chain oxidation, on A~ fibril growth rates. Within chapters 2 and 3 of this thesis is a discussion of various approaches to chemical synthesis of2-oxo-histidine with a view to theincorporation of the oxidised amino acids into A~ peptide using Fmoc approaches. Chapter 2 describes attempted chemical transformation of (protected) L-histidine into L-oxohistidine. Dimethyldioxirane oxidised Boc-His-OMe yielded products containing isopropylidene groups, while oxidation using a Cu(II)/ascorbate generated 2-oxo-histidine but gave very low yields. Within chapter 3, a successful synthesis of protected 2-oxo-histidine is described, via the known imidazolin-2-one-4-carboxylic. Chapter 4 analyses A~(l-40) fibrillation kinetics by treating the intact peptide with various oxidants. Contrary to previous reports, hydrogen peroxide alone did not slow fibrillation rates. Cu(II)/Cu(l)- catalysed oxidation increased the likelihood of amorphous aggregation over fibrillation. This thesis shows oxidation of A~ has a profound influence on fibril growth and that incorporation of a stable oxidised histidine into A~ is a realisable goal.EThOS - Electronic Theses Online ServiceGBUnited Kingdo
U-M president welcomes Google
No full textFour years after U-M President Mary Sue Coleman first talked with Google founder Larry Page about the idea of his company coming to Ann Arbor, the dream is a reality. The Ann Arbor offices already have more than 100 employees with many more on the way. Coleman and her top executive officers paid a visit to meet with the new staff, which includes 40 U-M graduates, to welcome Google to the neighborhood. First tour of new Ann Arbor division HQ Four years after U-M President Mary Sue Coleman first talked with Google founder Larry Page about the idea of his company coming to Ann Arbor, the dream is a reality. The Ann Arbor offices already have more than 100 employees with many more on the way. Coleman and her top executive officers paid a visit to meet with the new staff, which includes 40 U-M graduates, to welcome Google to the neighborhood.http://deepblue.lib.umich.edu/bitstream/2027.42/93348/1/MSC_Google_Slideshow.mo
Commodifying multicultures: urban regeneration and the politics of space in Spitalfields
No full textPhDSpitalfields, within close distance to the City of London. has been subject to intense
regeneration and gentrification in recent years. This thesis investigates the use of
culture in promoting urban regeneration. This thesis analyses the role of
multiculturally based regeneration in Spitalfields and assesses the possibilities for
civic engagement in a number of recent regeneration initiatives. I argue that
regeneration in Spitalfields has taken a cultural turn, and that a new set of discourses
is present in regeneration practices. These new forms of regeneration practices
demand a different kind of interpretation. This distinctiveness in policy consists of
the use and mobilisation of 'culture' and 'multicultural capital' as tools for
regeneration. Most notably the study's timing during a phase of intense change sets it
apart as one of the few studies undertaken of the complex relationship between the
new cultural industries, multicultural capital and the practice of selling places. The
study's theoretical framework draws from a range of inter-disciplinary literature on
urban space. cultural politics and feminist theory.
In capturing a series of moments that took place between 2000 and 2003,1
analyse a range of regeneration initiatives but focus closely on three case studies: the
construction of Banglatown in Brick Lane, the Rich Mix Centre for London, and the
annual street festivals/melas that took place in 2001 and 2002. I focused on two sets
of respondents - young people and young Muslim women whose experiences of
regeneration raise unsettling questions of inclusion and exclusion in/through space.
Cumulatively these sites are key examples of Spitalfields' multi-cultural spaces.
They extend a sense of promise to all its residents in the hope of a cosmopolitan
future or progressive city politics.
The tensions from these cultural strategies pose challenges for thinking about the
place of citizenship in urban multicultures. The research findings point to a
sophisticated understanding of the relationship of ethnicity, gender, commerce and
public space
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