957 research outputs found
Digital intermediaries in pandemic times: social media and the role of bots in communicating emotions and stress about Coronavirus
No full textThis project contains the relevant files, including R code for the publication: Elayan S. and Sykora M. (2024) Digital intermediaries in pandemic times: social media and the role of bots in communicating emotions and stress about Coronavirus, Journal of Computational Social Science, doi:10.1007/s42001-024-00314-2
A parametric method to enhance decision-making in airport terminal development
No full textBusiness cases and investment decisions for airports and passenger terminals are generally based on annual flight and passenger number forecasts. However, the design of a new passenger terminal is based on much shorter-term demands, typically a “peak hour”. Conventionally there are two methods for bridging the gap between annual demands and these short-term demands: a design day schedule, or a ratio-based method. There are important practical and theoretical limitations with these methods. In this paper, a complementary method is proposed that provides an improved theoretical basis for determining short-term demands and which can form part of a more informed decision-making process. Its application to a recent terminal design case is discussed
Deliberative Qualities of Online Abortion Discourse: Incivility and Intolerance in the American and Irish Abortion Discussions on Twitter
No full textThis project contains the classifier code and dictionary files for the publication of: Oh, D., Elayan, S., & Sykora, M. (2023). Deliberative Qualities of Online Abortion Discourse: Incivility and Intolerance in the American and Irish Abortion Discussions on Twitter. Journal of Deliberative Democracy, 19(1)
Resource Sharing in Wireless Networks : The SAPHYRE Approach
No full textPhysical resource sharing between wireless operators and service providers is necessary in order to support efficient, competitive, and innovative wireless communication markets. By sharing resources, such as spectrum or infrastructure, which are usually exclusively allocated interference is created on the physical layer. Therefore, the economic gains, regulatory overhead, and engineering efforts need to be addressed by a consolidated cross-layer approach. This paper describes briefly the approach taken by the EU FP7 project SAPHYRE.Original Publication: Eduard A. Jorswieck, Leonardo Badia, Torsten Fahldieck, David Gesbert, Stefan Gustafsson, Martin Haardt, Ka-Ming Ho, Eleftherios Karipidis, Andreas Kortke, Erik G. Larsson, Hrjehor Mark, Maciej Nawrocki, Radoslaw Piesiewicz, Florian Römer, Martin Schubert, Jan Sykora, Peter Trommelen, Bram van den Ende and Michele Zorzi, Resource Sharing in Wireless Networks: The SAPHYRE Approach, 2010, Proceedings of the Future Network and Mobile Summit Conference, 1-8</p
Expert Mission on Validation and Verification of EOP and Development of AM guidelines for NPP Kozloduy
No full textThe University of Pisa participated in a number of activities organized by the International Atomic Energy Agency (IAEA). In connection with the majority of those activities the UNIPI author had the opportunity to know the details of the operational conditions of current Nuclear Power Plants (NPP) and to comment on various aspects mostly connected with the safety and the safety planning in case of accidents. The mission at the Kozloduy Nuclear site in Bulgaria deals with the validation of the Emergency Operating Procedures (EOP) including the transition from EOP to AMP (Accident Management Procedures). Both EOP and AMP are essential to prevent disastrous core melt scenarios (and have been effective for many years in this connection)
Beer, Brats, Cheese, and-- Baseball: The History and Impact of Baseball in Wisconsin
No full textFrom the 1800s baseball became a passion for the citizens of the United States. Wars, recessions and scandals could not bring down what is known as "America's Pastime." However baseball and other professional sports have been getting a bad name since historians and economist have started to look at the correlation between the team and the community. The notion of, "build us a new stadium at the cost of the tax payers or we are taking our team elsewhere" has been a common trend since 1950's. By looking at Appleton and Milwaukee this paper will look at the impacts baseball has on these communities both culturally and economically from 1966 to 2012
Web 1.0 to Web 2.0: an observational study and empirical evidence for the historical r(evolution) of the social web
No full textApplications such as Twitter, Facebook or Youtube have taken the internet community by storm and have literally initiated a revolution in online communication. These social media applications are also often referred to by the general, somewhat vague but yet eloquent term - Web 2.0. The term implies a perceived second generation of World Wide Web, i.e., Web 1.0 → Web 2.0. Nevertheless the reference to a 'second' version of the web is misleading, since there was not any specific technical update of the World Wide Web. Hence, this paper empirically explores social media in a historical context as it has evolved and driven a revolution in online communication over the last decade. A unique historical dataset, made available by the Wayback Machine Internet Archive project is employed in order to provide an accurate historical record of the primary web design and related elements that drove the evolution towards a more social and interactive web. This study presents a unique contribution to related academic literature
TRAIL/bortezomib cotreatment is potentially hepatotoxic but induces cancer-specific apoptosis within a therapeutic window
No full textTumor necrosis factor-related apoptosis-inducing ligand (TRAIL) represents a novel promising anticancer biotherapeutic. However, TRAIL-resistant tumor cells require combinatorial regimens to sensitize tumor but not normal cells for TRAIL-induced apoptosis. Here, we investigated the mechanism of the synergistic antitumor effect of bortezomib in combination with TRAIL in hepatoma, colon, and pancreatic cancer cells in comparison to the toxicity in primary human hepatocytes (PHH). TRAIL cotreatment at high but clinically relevant concentrations of bortezomib caused toxicity in PHH which potentially limits the clinical applicability of bortezomib/TRAIL cotreatment. However, at low concentrations of bortezomib TRAIL-resistant hepatoma, colon and pancreatic cancer cell lines but not PHH were efficiently sensitized for TRAIL-induced apoptosis. RNA interference and TRAIL receptor blockage experiments revealed that in bortezomib-treated hepatoma cells TRAIL-R1/TRAIL-R2 up-regulation, enhanced TRAIL DISC formation and cFLIPL down-regulation in addition to accumulation of Bak cooperatively sensitized for TRAIL. Bim, although accumulated upon bortezomib treatment, did not play a causal role for TRAIL sensitization in Hep3b cells. Combined treatment with bortezomib and TRAIL massively reduced the clonogenic capacity of hepatoma cells in vitro. Surviving clones could be resensitized for repeated TRAIL treatment. CONCLUSION: Bortezomib/TRAIL cotreatment bears the risk of severe hepatotoxicity at high but clinically relevant concentrations of bortezomib. However, within a wide therapeutic window bortezomib sensitized different cancer cells but not PHH for TRAIL-induced apoptosi
Archaeological and biological examination of “The Mystery Wreck” (8MO143) off Vaca Key, Monroe County, Florida: A Report Submitted to the Florida Keys National Marine Sanctuary in Fulfillment of a NOAA Maritime Heritage Program Mini-grant
No full textDuring the summer of 2004, the Florida Bureau of Archaeological Research Underwater Archaeology team undertook a project to relocate, assess, and record thirteen of the shipwrecks of the 1733 Spanish Plate Fleet in the Florida Keys. One source of background information that they used was a commercially available videotape entitled “Galleon Hunter,” produced by Don Ferguson. Aside from the 1733 wrecksites, the video features another site, locally known as “the Mystery Galleon,” that was shown to Ferguson by local diver Stefan Sykora. Using location numbers supplied in Ferguson’s video, Roger Smith, Della Scott-Ireton, and Dave McCampbell relocated the site in Hawk Channel, off the city of Marathon. Later, the site further was examined by Smith, Jennifer McKinnon, and Jason Raupp, who made initial sketches, still photos, and video recordings.ReportSubmitte
Natuurtechnische en civieltechnische aspecten van rivierdijkvegetaties.
No full textWelke structuur en floristische samenstelling dient de begroeiing van een rivierdijk te hebben, die enerzijds een zo goed mogelijke waarborg biedt tegen aantasting door watererosie en anderzijds de natuurwaarde van dit biotoop zoveel mogelijk in stand houdt? 2. Welke voorwaarden dienen aan materiaal, ontwerp en uitvoering van dijkverhogingen en/of dijkverzwaringen gesteld te worden ten einde het sub 1. genoemde doel te bereiken? 3. Welk beheer dient na de sub 2. genoemde aanleg ten aanzien van de begroeiing gevoerd te worden
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