14,543 research outputs found

    The 2D/3D dynamics of wall-bounded low-Rm magnetohydrodynamic (MHD) turbulence

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    With this experimental study, we give evidence that the dynamics of low-Rm MHD turbulence depends on the diffusion length l_z, which corresponds to the distance over which the Lorentz force is able to diffuse momentum before it is balanced by inertia

    One-way multigrid method in electronic-structure calculations

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    We propose a simple and efficient one-way multigrid method for self-consistent electronic structure calculations based on iterative diagonalization. Total energy calculations are performed on several different levels of grids starting from the coarsest grid, with wave functions transferred to each finer level. The, only changes compared to a single grid calculation are interpolation and orthonormalization steps outside the original total energy calculation and required only for transferring between grids. This feature results in a minimal amount of code change, and enables us to employ a sophisticated interpolation method and noninteger ratio of grid spacings. Calculations employing a preconditioned conjugate gradient method are presented for two examples, a quantum dot and a charged molecular system. Use of three grid levels with grid spacings 2h, 1.5h, and h decreases the computer time by about a factor of 5 compared to single level calculating

    Structural and mutagenic analysis of the RM controller protein C.Esp1396I

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    Bacterial restriction-modification (RM) systems are comprised of two complementary enzymatic activities that prevent the establishment of foreign DNA in a bacterial cell: DNA methylation and DNA restriction. These two activities are tightly regulated to prevent over-methylation or auto-restriction. Many Type II RM systems employ a controller (C) protein as a transcriptional regulator for the endonuclease gene (and in some cases, the methyltransferase gene also). All high-resolution structures of C-protein/DNA-protein complexes solved to date relate to C.Esp1396I, from which the interactions of specific amino acid residues with DNA bases and/or the phosphate backbone could be observed. Here we present both structural and DNA binding data for a series of mutations to the key DNA binding residues of C.Esp1396I. Our results indicate that mutations to the backbone binding residues (Y37, S52) had a lesser affect on DNA binding affinity than mutations to those residues that bind directly to the bases (T36, R46), and the contributions of each side chain to the binding energies are compared. High-resolution X-ray crystal structures of the mutant and native proteins showed that the fold of the proteins was unaffected by the mutations, but also revealed variation in the flexible loop conformations associated with DNA sequence recognition. Since the tyrosine residue Y37 contributes to DNA bending in the native complex, we have solved the structure of the Y37F mutant protein/DNA complex by X-ray crystallography to allow us to directly compare the structure of the DNA in the mutant and native complexes

    Measurement of Differential ttˉ{\rm t}\bar{\rm t} Cross Sections at 7 TeV

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    A measurement is presented of the normalized differential cross sections of top-quark pair production in pp collisions at a center of mass energy of 7 TeV, using 1.1 fb1^{-1} of data collected in 2011 by the CMS experiment. The measurement is performed using five different final states with one or two muons or electrons in the final state. The event selections yield high purity ttˉ{\rm t}\bar{\rm t} samples. Kinematic reconstructions are performed to obtain full information of the top quarks, the ttˉ{\rm t}\bar{\rm t} system and the final state leptons. The results are compared to several QCD predictions up to next-to-leading order

    Density-functional study of small molecules within the Krieger-Li-Iafrate approximation

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    We report density-functional studies of several small molecules (H(2), N(2), CO, H(2)O, and CH(4)) within the Krieger-Li-Iafrate (KLI) approximation to the exact Kohn-Sham local exchange potential, using a three-dimensional real-space finite-difference pseudopotential method. It is found that the exchange-only KLI approximation leads to markedly improved eigenvalue spectra compared to those obtained within the standard local-density approximation (LDA), the generalized gradient approximation (GGA), and the Hartree-Fock (HF) method. For structural properties, exchange-only KLI approximation results are close to the corresponding HF values. We find that the addition of LDA or GGA correlation energy functionals does not lead to systematic improvements. [S1050-2947(99)08111-1]

    Commensurations of Aut(FN){{\rm{Aut}}}(F_N) and its Torelli subgroup

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    For N3N \geq 3, the abstract commensurators of both Aut(FN){{\rm{Aut}}}(F_N) and its Torelli subgroup IAN{{\rm{IA}}}_N are isomorphic to Aut(FN){{\rm{Aut}}}(F_N) itself.Comment: 30 pages, 5 figures. Version accepted to appear in GAF

    Chapter 68 - Immunisation in Europe

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    Key Features Gain a complete understanding of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well an epidemiology and public health and regulatory issues. Update your knowledge of both existing vaccines and vaccines currently in the research and development stage. Get complete answers on each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies. Analyze the cost-benefit and cost-effectiveness of different vaccine options. Clearly visualize concepts and objective data through an abundance of tables and figures

    Triangular Constellations in Flows

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    Particles advected on the surface of a fluid can exhibit fractal clustering. The local structure of a fractal set is described by its dimension DD, which is the exponent of a power-law relating the mass N{\cal N} in a ball to its radius ε\varepsilon: NεD{\cal N}\sim \varepsilon^D. It is desirable to characterise the {\em shapes} of constellations of points sampling a fractal measure, as well as their masses. The simplest example is the distribution of shapes of triangles formed by triplets of points, which we investigate for fractals generated by chaotic dynamical systems. The most significant parameter describing the triangle shape is the ratio zz of its area to the radius of gyration squared. We show that the probability density of zz has a phase transition: P(z)P(z) is independent of ε\varepsilon and approximately uniform below a critical flow compressibility βc\beta_{\rm c}, which we estimate. For β>βc\beta>\beta_{\rm c} the distribution appears to be described by two power laws: P(z)zα1P(z)\sim z^{\alpha_1} when 1zzc(ε)1\gg z\gg z_{\rm c}(\varepsilon), and P(z)zα2P(z)\sim z^{\alpha_2} when zzc(ε)z\ll z_{\rm c}(\varepsilon)

    Exact two-dimensionalization of low-magnetic-Reynolds-number flows subject to a strong magnetic field

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    We investigate the behavior of flows, including turbulent flows, driven by a horizontal body-force and subject to a vertical magnetic field, with the following question in mind: for very strong applied magnetic field, is the flow mostly two-dimensional, with remaining weak three-dimensional fluctuations, or does it become exactly 2D, with no dependence along the vertical? We restrict attention to low-magnetic-Reynolds number (Rm) flow. Because liquid metals have low magnetic Prandtl number, such low-RmRm flows can have a kinetic Reynolds number as large as one million and therefore be strongly turbulent. We first focus on the quasi-static approximation, i.e. the asymptotic limit of vanishing magnetic Reynolds number Rm << 1: we prove that the flow becomes exactly 2D asymptotically in time, regardless of the initial condition and provided the interaction parameter N is larger than a threshold value. We call this property absolute two-dimensionalization: the attractor of the system is necessarily a (possibly turbulent) 2D flow. We then consider the full-magnetohydrodynamic equations and we prove that, for low enough Rm and large enough N, the flow becomes exactly two-dimensional in the long-time limit provided the initial vertically-dependent perturbations are infinitesimal. We call this phenomenon linear two-dimensionalization: the (possibly turbulent) 2D flow is an attractor of the dynamics, but it is not necessarily the only attractor of the system. Some 3D attractors may also exist and be attained for strong enough initial 3D perturbations. These results shed some light on the existence of a dissipative anomaly for magnetohydrodynamic flows subject to a strong external magnetic field
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