6,830 research outputs found
Modeled Cd deposition in a developping marsh.
No full text<p>Modeled evolution of marsh elevation and Cd deposition. Elevation of the marsh and mean high water level (MHWL), both in m TAW (Belgian reference height) on the left Y-axis. Cd deposition (µg cm<sup>−2</sup> a<sup>−1</sup>) on the right Y-axis.</p
Investigation of celiac disease according to Marsh classification in childhood
No full textBackground: Celiac disease (CD) is an autoimmune disorder of the small intestine related to gluten. CD is diagnosed by the evaluation of histologic findings according to the Marsh classification.Objectives: To evaluate the clinical and laboratory differences of CD according to Marsh classification.Patients and method: The records of ?Marsh 2 histologically diagnosed 132 cases were evaluated.Results: It was determined that 7(5.3%) cases were Marsh 2, 32(24.2%) were Marsh 3a, 73(55.3%) were Marsh 3b, and 20(15.1%) were Marsh 3c. Vomiting in Marsh 2 was significantly lower than Marsh 3b and Marsh 3c (respectively, 14.3% vs. 56.9%, p=0.029; and 14.3% vs. 75%, p=0.005). Hemoglobin was significantly higher in Marsh 2 than Marsh 3b and Marsh 3c (respectively, 11.9±1.7 vs. 10.5±1.6 g/dl, p=0.038 and; 11.9±1.7 vs. 9.8±1.6 g/dl, p=0.005). Positive detection ratio for tTG IgA was significantly lower in Marsh 2 than Marsh 3a, Marsh 3b and Marsh 3c (respectively, 66.7% vs. 100%, p<0.001; 66.7% vs. 100%, p<0.001; and 66.7% vs. 94.1%, p=0.003). After the onset of gluten free diet, the time passed for the disappearance of tTG IgA seropositivity is significantly shorter in Marsh 2 than Marsh 3c (6±3.6 vs. 9.7±2.5 months, p=0.017).Conclusions: Gastrointestinal symptoms are more frequent in patients with severe small intestinal mucosal injury. tTG IgA seropositivity is associated with more severe disease. Clinical and laboratory findings of the patients are exacerbated when histopathological findings improve in CD.Bangladesh Journal of Medical Science Vol.16(2) 2017 p.259-265</jats:p
Equations defined using gene expression and histological data resolve coeliac disease biopsies within the Marsh score continuum
No full textBackground/Aim: The gold standard diagnostic for coeliac disease (CD) is subjective histological assignment of biopsies into the Marsh score categories. It is hypothesized that discrete Marsh score categories can be quantitatively resolved into a continuum using discriminant equations defined using histological and gene expression data. Therefore, the aim of this study was to use a combination of histological and gene expression data to develop equations that classify CD patient biopsies into a quantitative Marsh score continuum which could be used by clinicians to monitor CD treatment efficacy. Methods: Both empirical and simulated gene expression and histological data were used to define predictive Marsh score equations. The distances of treated sample biopsies from the Marsh score standards were determined using the Mahalanobis distance calculation. Results: Three function, high resolution discriminant equations derived from simulated data were used to accurately classify 99.6% of simulated and empirically derived biopsy data. The first function resolved active (Marsh type 3) CD from mild (Marsh type 1) CD. The second function resolved normal (no specific pathology) biopsies from mild CD. The third function resolved active Marsh score 3 into a and b subcategories. Finally, measuring the Mahalanobis distance enabled the conversion of discrete Marsh score categories into a continuum. Conclusions: This proof-of-concept study successfully demonstrated that the discrete Marsh score scale can be converted into a quantitative continuum capable of high resolution monitoring of patient treatment efficacy using equations defined by gene expression and histology data
Usefulness of both IEL flow cytometric pattern and IF pattern for the diagnosis of CD in patients with lymphocytic enteritis (Marsh 1 type lesion).
No full text<p>Usefulness of both IEL flow cytometric pattern and IF pattern for the diagnosis of CD in patients with lymphocytic enteritis (Marsh 1 type lesion).</p
Classified Word List, given by Amy Cooper in Chilliwack Halkomelem, 24 November 1971. Track 1.
No full textFirst words on track: "I'm going to the strawberry patch"; "Marsh"; "Moss". On CD case: "Tape 37 - Side 2"
Author Co-Citation Analysis (ACA): a powerful tool for representing implicit knowledge of scholar knowledge workers
No full textIn the last decade, knowledge has emerged as one of the most important and valuable organizational assets. Gradually this importance caused to emergence of new discipline entitled ―knowledge management‖. However one of the major challenges of knowledge management is conversion implicit or tacit knowledge to explicit knowledge. Thus Making knowledge visible so that it can be better accessed, discussed, valued or generally managed is a long-standing objective in knowledge management. Accordingly in this paper author co- citation analysis (ACA) will be proposed as an efficient technique of knowledge visualization in academia (Scholar knowledge workers)
Mechanisms for accumulation and migration of technetium-99 in saltmarsh sediments
No full textThis thesis describes the development of analytical methods for both the bulk determination of 99Tc, and determination of 99Tc in sequential extracts from sediments. These methods have been used to collect data, which, along with trace and major element data have been used to interpret the mechanisms for 99Tc input, migration and accumulation in saltmarshes. The inventory of 99Tc stored in the Thornflatt Saltmarsh, Esk Estuary has also been determined. The routine determination of 99Tc in bulk samples uses 99mTc as a yield monitor. Samples are ignited stepwise to 550°C and the 99Tc is extracted using 8M nitric acid. Many contaminants are precipitated with Fe(OH)3 and the Tc in the supernant is pre-concentrated and further purified using anion-exchange chromatography. Final separation of Tc from Ru is achieved by extraction of Tc into 5% TnOA in xylene from 2M sulphuric acid. The yield is determined by γ-spectrometric analysis of 99mTc. Determination of 99Tc is made by liquid scintillation counting. Typical recoveries are in the order of 70-95% and the method has a detection limit of 1.7 Bq/kg for a sample size of 10g. Determination of Tc in sequential extracts uses operationally defined procedures to extract: exchangeable Tc, reducible Tc and oxidisable Tc. An initial water wash is used to extract any occluded Tc and a final leach in 8 M nitric acid is used to dissolve any residual Tc. The isolation of 99Tc uses TEVA resin for Extracts 1-4 and the decontamination procedure developed for bulk analysis for Extract 5. 99mTc was used as a yield monitor, and determination of 99Tc is by liquid scintillation counting. Limits of detection were dependent on the amount of 99mTc tracer used but were found to be as low as 2.4 Bq/kg for a sample size of 2g. A study was made of the mechanisms responsible for the accumulation and migration of Tc in estuarine sediments using sediments collected from saltmarshes at Thornflatt, Carlaverock and the Ribble Estuary. 99Tc was present at determinable activities in all the sediment cores taken from these sites. Good correlations between Tc and CaO as well as CO3 concentrations and poor correlation between Tc and radionuclides adsorbed to inorganic detritus infer a direct input of 99Tc to marsh sediments. Determination of 99Tc in biota living on the marsh also showed that this was not a significant pathway for input of Tc to the sediments. Sequential extraction data imply sorption to an organic fraction of the sediment. Stable element and sequential extraction data indicates that Tc is readily oxidised and remobilised before reprecipitation where redox conditions are favourable. Data indicate a reduction potential between those of the MnIV to MnII reaction and the FeIII to FeII reaction is necessary for re-accumulation to occur, as suggested by published thermodynamic data. Data collected from reducing sediments imply that similar mechanisms are responsible for the accumulation of Mn (e.g. reduction by sulphate reducing bacteria) and the accumulation of Tc. The inventory of 99Tc held within the Thornflatt saltmarsh is proportionally less than that of 137Cs or 241Am when compared to discharges from Sellafield. However a higher proportion of 99Tc is transferred from Seliafield and incorporated into saltmarsh sediments than is suggested by previously published standard distribution coefficient data. Saltmarsh sediments are therefore a more important sink of 99Tc than extrapolations made from inventories of other radionuclides would suggest
Spatial distribution of soil organic carbon in an Irish salt marsh (Rogerstown Estuary)
No full textSalt marshes are globally widespread, found on low-lying coastal shores, and are highly effective at long-term carbon storage; thus, they are vital for climate change impact mitigation. Accurate carbon stock estimation requires an understanding of local-scale spatial variability of carbon storage and the facilitating processes. Few studies investigate the cumulative impact of controlling factors on within-site carbon distribution. This study utilises 60 cores from a salt marsh in Turvey Nature Reserve (Rogerstown Estuary), on the Irish east coast, to investigate spatial variability in soil organic carbon (SOC) content, alongside bio-sedimentary, and environmental factors. Mean carbon density (CD) was 11.1 ± 4.2 kg m−3 at 10-cm depth, ranging from 5.2 to 22 kg m−3 (423% increase) across the marsh. We recommend that to obtain measurements across the full range of the site, for small sample sizes (n < 20), random sampling should be used (mean difference between the site-wide CD and ‘subsample CD’ ranged from 0.04 (n = 10) to 0.29 (n = 5) kg m−3) and marsh edge clustering should be avoided. These results provide the first ever systematic record of local-scale (within ~ 800 m2) SOC and CD variability within an Irish east coast salt marsh and the variation of known influencing factors (including sedimentary and environmental). We also present the first study to systematically provide guidance on capturing marsh-wide SOC and CD most effectively based on limited sampling. The outputs help constrain uncertainties around scaled-up carbon accumulation estimates for regional, national and international inventories
Portfolio of recorded performances and exegesis: Messiaen’s musical language for the jazz pianist - an exploration through performance.
No full textMoving beyond Gunther Schuller’s Third Stream amalgamation of classical and jazz, this study explores whether the musical language of Olivier Messiaen can make a valid contribution to jazz piano performance. Initially, my project sought to answer such questions as: What elements of the musical language of Messiaen already exist in the jazz vocabulary? Am I able to extend this further? What are the timbral structures and pianistic effects within Messiaen’s musical language? What will be the most effective application of Messiaen’s musical language to jazz piano performance? Endeavouring to answer the final question led me to consider such aspects as whether the project should be limited to quoting Messiaen motifs, arranging Messiaen melodies, replacing jazz harmonic structures on standards with examples from Messiaen’s musical language or whether it would be better to approach the research conceptually. The work of Hubert Nuss provided encouraging reassurance that this was not an impossible task. In order to articulate this conception, the initial challenge was to decide how the classical and jazz worlds might meet in a ‘Messiaen’ technique. The approach adopted was similar to that used for undergraduate jazz study, namely, immersion in the piano scores and recordings of Messiaen’s music as well as by live performances. This was followed by the development and assessment of a contrived approach when specific techniques, such as tonal colourings or harmonic structures, were developed through prepared exercises and consciously included in my performance. It was then compared with an intuitive approach when no such precise parameters were established. This submission consists of CD recordings of two public recitals and an exegesis. It documents the development of this Messiaen technique and discusses its application in my performances. It also demonstrates the ways that Messiaen’s musical language can be used within jazz piano performance to provide a colour that distinguishes jazz piano performance in a competitive field.Thesis (M.Mus.) -- University of Adelaide, Elder Conservatorium of Music, 201
Spinal anaesthesia for brachytherapy for carcinoma of the cervix a comparison of two dose regimes of hypebaric bupivacaine
No full textIncludes abstract.Includes bibliographical references.The main purpose of the study was to help establish the best dose regimen of hyperbaric bupivacaine, when combined with intrathecal fentanyl, for spinal anaesthesia for brachytherapy for carcinoma of the cervix. This procedure is performed as a day case at Groote Schuur Hospital
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