389 research outputs found

    Specificity profile of venlafaxine and sertraline in major depression: metaregression of double-blind, randomized clinical trials.

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    Despite the well-known efficacy of selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) in the treatment of major depressive disorder, there is a lack of indications for each drug in different groups of patients. The aim of this study is to investigate the possible role of clinical sociodemographic factors as moderators of clinical response to venlafaxine (SNRI) and sertraline (SSRI). Research was performed on Medline and EMBASE for randomized control trials in English focused on sertraline and venlafaxine in the treatment of major depressive disorder and 59 studies were included. Clinical efficacy of each treatment was assessed on the basis of Hamilton Depressive Rating Scale and Montgomery-Asberg Depression Rating Scale. A metaregression analysis was performed to evaluate the role of clinical and sociodemographic factors as moderators of outcome, calculating the effect of each variable with the random-effects method. Gender, ethnicity and duration of depressive episode could have a role in prediction of clinical response to both antidepressants. Venlafaxine seems to have better effects in females and in Caucasian patients. Sertraline seems to be more efficacious in the treatment of females. Both drugs were more efficacious in patients who suffered a shorter episode of illness. Our results could represent an interesting point of view in the perspective of choosing the most suitable therapy based on clinical and social features for each patient. Metaregression is a retrospective analysis, based on the cumulative results of previous studies, so the lack of original data could represent the main limitation in this report and in the interpretation of the results obtained

    (Ri-)Scrivere di santi: sulle tracce di Agnese

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    L’articolo, seguendo una sollecitazione di Gennaro Luongo, recentemente scomparso, si interessa al dossier agiografico di Agnese. L’autrice lo ripercorre fra storia e leggenda, documenti letterari e testimonianze monumentali, iconografia e pratiche devozionali. Ciò le consente di mettere in evidenza le trasformazioni e continue ri-funzionalizzazioni del personaggio, nonché di avanzare alcune ipotesi sulle ragioni che presiedettero a questi continui processi di rilettura.The article following a solicitation by Gennaro Luongo, recently deceased, deals with the hagiographic dossier of Agnese. The author traces it between history and legend, literary documents and monumental evidences, iconography and devotional practices. This allows her to highlight the transformations (modifications) and continuous re-functionalizations of the character, as well as to advance some hypotheses on/regarding the reasons that presided over these continuous re-reading processes

    Giuseppe Dessí

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    Twenty-five years after the death of one of the most refined and secluded writers of the second half of the 20th century, the complete catalogue of works and author papers in the Giuseppe Dessí Collection is available, thanks to the work and philological expertise of Agnese Landini. The filing of the material, deposited in the Contemporary Archives of the Gabinetto Vieusseux in Florence, allows to retrace the complete bibliography of the published and unpublished works of the Sardinian writer and, while telling the story of a narrative path through documents, it eases access to notes and drafts of novels, short stories, plays, anthologies, translations, essays, poems, interviews

    Osservazioni su un apografo della farrago pucciana (Roma, Biblioteca Casanatense, vol. inc. 694)

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    This paper offers an analysis of the marginalia to Catullus’ poems contained in a Roman incunable (Biblioteca Casanatense, Vol. Inc. 694). Most of these notes can be traced back to the so called ‘farrago pucciana’, annotations to Catullus, Tibullus and Propertius by Francesco Pucci, a disciple of Poliziano. These marginalia were held in high esteem by 16th-century humanists, and over twenty copies of them survive today. In this paper the exemplar of the Casanatense incunable is identified and some hypotheses regarding the author of this copy and his connections with Piero Vettori are discussed, along with an outline of the tradition of the farrago pucciana

    Per la biografia di fr. Iacopo Passavanti OP (1302 ca.-1357)

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    Iacopo Passavanti is currently known for his sermons and as the author of one of the oldest theological treatises, which was redacted both in Latin and Vernacular. However, he was also a leading member of the Order of Preachers and a spokesman of an innovative reli- gious and cultural project which, it seems, he held in common with the entirety of the Order of St. Dominic. With this paper, we intend to recreate the friar’s biography and shed light on his works. Thus, we will proceed with a critical reading of the documents that concern him, which we organized, for the occasion, in a new Diplomatic Code

    Promoting reading skills in Latvian language lessons in primary school in the 3rd grade

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    Darba temats: Lasītprasmes sekmēšana latviešu valodas stundās sākumskolā 3. klasē Darba autore: Agnese Ozoliņa Darba vadītāja: Antra Randoha Darba mērķis: teorētiski un praktiski izzināt pedagoģiskās metodes lasītprasmes sekmēšanai sākumskolas 3. klasē. Darba teorētiskajā daļā tika analizēta teorētiskā literatūra par lasītprasmes jēdziena skaidrojumu. Darba autore apkopoja lasītprasmes sekmēšanas stratēģijas un metodes. Izpētīts sākumskolas vecuma bērnu attīstības īpatnības. Darba empīriskajā daļā tika izveidots pētījuma plāns un aprakstītas pētīšanas metodes. Darba autore izveidoja skolēnu raksturojumu, aprakstot pētāmo problēmu. Tika izveidoti lasītprasmes vērtēšanas kritēriji. Lai sekmētu skolēnu lasītprasmi tika izmantotas dažādas metodes un stratēģijas, gan ārpusskolas aktivitātēm, gan mācību stundas ietvaros. Iegūtie rezultāti tika analizēti un salīdzināti. Darba apjoms: 48 lapaspuses, 12 attēli, 4 tabulas, 32 literatūras avoti. Atslēgvārdi: 3. klase, skolēni, lasītprasme, latviešu valoda, skola.The topic of the work: Promoting reading skills in Latvian language classes in primary school in the 3rd grade Author of the work: Agnese Ozoliņa Supervisor: Antra Randoha The purpose of the work: to theoretically and practically learn the pedagogical methods for promoting reading skills in the 3rd grade of primary school. The theoretical part of the work analyzed the theoretical literature on the explanation of the concept of literacy. The author of the paper summarized the strategies and methods of promoting literacy. Peculiarities of development of children of primary school age have been studied. In the empirical part of the work, only a research plan is created, and research methods are described. The author of the work created a description of the students, describing the problem under study. Evaluative literacy assessment criteria were created. Various methods and strategies were used to promote students' reading skills, both in extracurricular activities and in the classroom. The obtained results were analyzed and compared. Work volume: 48 pages, 12 images, 4 tables, 32 literature sources. Keywords: 3rd grade, students, literacy, Latvian language, school

    Promotion of social skills in a pre-school educational institution for 2-3 year old children

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    Kvalifikācijas darba tēma: Sociālo prasmju sekmēšana pirmsskolas izglītības iestādē 2 – 3 gadus veciem bērniem Darba autore: Agnese Altmane Pētījuma mērķis: Izpētīt sociālo prasmju apguves sekmēšanu pirmsskolas izglītības iestādē 2 – 3 gadus veciem bērniem. Pētījuma metodes: Teorētiskās literatūras analīze un pedagoģiskā novērošana, pedagoģiskā izmēģinājumadarbība. Teorētiskajā daļā tika analizēta literatūra par kvalifikācijas darba tēmu, praktiskajā daļā ir veikta pedagoģiskā novērošana sociālo prasmju sekmēšanā pirmsskolas izglītības iestādē 2 – 3 gadu veci bērni. Darba apjoms: kvalifikācijas darba saturs izklāstīts 36 lppusēs,3 nodaļās, 9 apakšnodaļās, ir 4 tabulas, 12 attēli, 9 pielikumi. Atslēgas vārdi: Sociālās prasmes, rotaļa, 2 - 3 gadu veci bērni, pedagoģiskais process pirmsskolāSubject of qualification work: Promotion of social skills in a pre-school educational institution for 2-3 year old children Author of the work: Agnese Altmane Objective of the study: Explore the promotion of social skills in pre-primary education for children aged 2 to 3 years. Study methods: Analysis of theoretical literature and pedagogical observation, teaching testing. The theoretical part analysed the literature on the subject of qualification work, the practical part of which has carried out pedagogical follow-up in the promotion of social skills in the pre-primary educational establishment for children aged 2 to 3. Volume of work: The content of the qualification work is set out in 36 pages, 3 chapters, 9 sub-sections, 4 tables, 12 pictures, 9 annexes. Key words: Social skills, playing, children 2-3 years old, pedagogical process in preschoo

    Conversation and learning in early childhood education: what works best for children’s cognitive development and how to improve pupil engagement?

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    Generally, all schools state that they are children-focused, but this aim is most visible in communication if children have autonomy and freedom of expression. The purpose of this article is twofold: first, to describe some features of conversations’ in early childhood education, and, second, to investigate the conditions in which pupils are more engaged and more participative. The research was carried out by the author observing real daily activity in preschools around Reggio Emilia. Conversations are intentionally defined and started by teachers. The teachers’ open and closed questions are analysed and categorised, as well as the children’s answers and child-initiated interactions. Results indicate that classroom discourse can be categorised with four kinds of topics, showing that narrative contexts and shared knowledge contexts are the most promising situations to promote children’s engagement, through longer children’s interactions and complex child-initiated interactions. Findings are discussed also in relation to the groups’ numerosity

    The use of the visualization method in the acquisition of mathematics in 7th to 9th grade

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    Bakalaura darbs ir par vizualizācijas metodes izmantošanu matemātikas apguvē 7.-9.klasē, darba autore ir Agnese Saukuma, darba vadītājs asoc. prof. Jānis Mencis. Bakalaura darba izstrādes laikā, akcentējot pētījuma mērķi - noskaidrot vizualizācijas līdzekļu pielietošanas iespējas matemātikas apguvē 7.-9. klasē un tās ietekmi uz skolēnu mācību sasniegumiem, tika analizēta vizualizācijas metode, skolēnu attīstības īpatnības pusaudžu vecumposmā, vizualizācijas līdzekļu pielietošanas iespējas matemātikas apguvē. Tika veikts empīriskais pētījums, kurā tika izmantotas vairākas pētīšanas metodes. Iegūtie rezultāti atļauj apgalvot, ka ar atbilstošu vizualizācijas līdzekļu palīdzību skolēns var ieraudzīt, izprast, pielietot un paust pamatotu viedokli par matemātiskajām darbībām un to likumsakarībām, tādējādi vizualizācijas metodes izmantošana mācīšanās procesā ir būtisks faktors, kas uzlabo skolēnu mācību sasniegumus. Bakalaura darba apjoms ir 71 lapaspuse (ar pielikumiem). Bakalaura darba attēlu skaits - 70, tabulu skaits - 8, bibliogrāfisko vienību skaits - 54, pielikumu skaits - 5.The bachelor paper is about the use of the visualization method in the acquisition of mathematics in 7th to 9th grade; the author of the paper is Agnese Saukuma, the advisor is Assoc. Prof. Jānis Mencis. During the elaboration of the bachelor paper, emphasizing the aim of the research - to find out the possibilities of applying visualization tools in learning mathematics in 7th to 9th grade and its impact on students’ learning achievements, the author analysed the method of visualization, the peculiarities of students' development in adolescence, the possibilities of using visualization tools in the acquisition of mathematics. An empirical study was performed using several research methods. The obtained results allow stating that with the help of appropriate visualization tools the student can notice, understand, apply, and express a reasonable opinion about mathematical operations and their regularities, thus the use of the visualization method in the learning process is an important factor that improves students' learning achievements. The length of the bachelor paper is 71 pages (with appendices). The number of figures in the bachelor paper - 70, the number of tables - 8, the number of bibliographic units - 54, and the number of appendices - 5

    Short and long vowel differentation in grade 2 with students of phonematics disabilities

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    Diplomdarba nosaukums: “Īso un garo patskaņu diferencēšana 2. klases skolēniem ar fonemātiskiem traucējumiem” Darba autore: Agnese Sprūģe Darba vadītāja: Mg. paed. Ilze Vilka Darba saturs: 51 lappuses, 5 attēli, 15 tabulas, 9 pielikumi. Pētījuma mērķis: teorētiski izpētīt un praktiski pārbaudīt 2. klases skolēnu fonemātiskās uztveres sekmēšanu īso un garo patskaņu diferencēšanā. Pētījuma hipotēze: fonemātiskās uztveres pilnveide 2. klases skolēniem īso un garo patskaņu atšķiršanā būs sekmīga, ja koriģējoši attīstošā darbībā: •tiks ņemts vērā skolēna attiecīga vecumposma attīstības likumības, •tiks izmantoti atbilstīgi vingrinājumi, darba metodes un paņēmieni. Pētījuma teorētiskājā daļā diplomdarba autore analizējusi dažādu autoru atziņas par jaunāko klašu skolēnu raksturojumu veselumā izvēlētās problēmas kontekstā, fonemātiskās uztveres pilnveides iespējām īso un garo patskaņu diferencēšanā, fonemātiskās nepietiekamības cēloņiem un raksturojumu, kā arī īso un garo patskaņu raksturojumu latviešu valodā. Prakstiskajā daļā darba autore apraksta pētniecisko darbību 2. klases skolēniem ar fonemātiskiem traucējumiem, ņemot vērā teorētiskājā daļā gūtās zināšanas. Pētījuma noslēgumā darba autore izdara secinājumus, ka ar dažādu metožu un vingrinājumu palīdzību ir iespējams uzlabot fonemātisko nepietiekamību 2. klases skolēniem.The theme of the diploma paper: Short and long vowel differentation in grade 2 with students of phonetics disabilities. Author of diploma: Agnese Sprūģe Advisor: Ilze Vilka Content of diploma: 51 pages, 5 pictures, 15 charts, 9 appendices Research goal: theoreticaly find out and practicaly prove phonetic perceptions in order to promote differentation of short and long vowels in grade 2. Research hypothesis: Phonemic perceptions correction in order to differentiate short and long vowels in grade 2 is successful if: •individual identity of child’s age group development is respected and taken into account; •appropriate teaching aid, methodology and working methods are used. In the theoretical part of diploma, author has analyzed different author ideas about the youngest school child’s characteristiscs in the contect of a problem, improve phonetic perceptions in order to promote differentation of short and long vowels, phonemic perception disordes and characteristics and short and long vowel characteristics in Latvian. In the empirical part of the study, the author describes her practical research practices with 2nd grade students who have phonetic disorders on the basis of theoretical knowladge. In the final part of the study the author of diploma paper concludes that with the help of differend methods and exercises it is possible to improve phonemic disorders with grade 2 children
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