1,756,811 research outputs found
Mark D. Diggs Vietnam War collection [DIGITAL CONTENT]
No full textThis collection records the service of Mark D. Diggs in the Vietnam War
Sectional map of Lincoln County, South Dakota.
No full textCadastral map showing drainage, section lines and numbers, land ownership, landowners' names, and railroads.[Cpyright Mark D. Scott].LC Land ownership maps, 85
Mark D. Wiese
No full textMark D. Wiese is the manager of the logistics element for NASA’s Gateway program. In this role, he provides project management expertise and strategic vision for commercial spacecraft, launch vehicles and integration services to advance the agency’s gateway lunar orbiting platform of complex systems, utilization payloads, and research and development technologies. Wiese oversees the design, development, test and evaluation of the spacecraft along with the program’s integration of commercial logistics missions to the gateway.
Wiese was appointed to the Federal Senior Executive Service in January 2017 as the deputy director of the Safety and Mission Assurance (S&MA) Directorate at NASA’s Kennedy Space Center in Florida. His contributions focused primarily on leadership development and strategic planning to ensure safety and mission success of Kennedy-managed programs as well as the center transition into a multi-user spaceport.
Wiese began his career with Science Applications International Corp. (SAIC) in 1998 as a Geographic Information Systems technician. In the years following, he transitioned to SAIC’s S&MA team at Johnson Space Center in Houston, Texas, where he worked in NASA’s Mission Control Center and later joined the Launch Services Program (LSP) at Kennedy as a quality engineer.
Wiese joined NASA in 2003 as a mission assurance manager for LSP, where he was responsible for leading the S&MA efforts for NASA’s Atlas V vehicle certification that led to the successful launches of the Mars Reconnaissance Orbiter and Pluto New Horizons missions. In 2006, Wiese was promoted to support the Space Shuttle Program as deputy chief of the Launch Vehicle Processing (LVP) S&MA Division, rose to division chief in 2007, and was responsible for planning, organizing and directing activities required to gain insight, assess risk, and influence safe and successful launch operations for the final 20 space shuttle missions and the Ares I-X development flight test.
In the years spanning from 2010 to 2016 under LSP, Wiese was appointed to chair for the Expendable Launch Vehicle Integrated Services 2 (ELVIS 2) Source Evaluation Board (SEB), made chief of the Flight Projects Branch of LSP’s Business Office, and then became chief of LSP’s Flight Project Office (FPO). Wiese received the NASA Outstanding Leadership Medal in 2010 for his role in transforming the culture and improving the workforce dynamics of the LVP S&MA team and again in 2012 for his efforts in the award and contract phase-in of ELVIS 2.
In his chief roles supporting LSP, Wiese was instrumental in developing the Venture Class Launch Services Contracts (VCLS), which proved to be a significant milestone for assuring long-term launch services for an emerging commercial small-satellite market. Wiese was responsible for over $500M/year in launch service contracts, as well as the successful launch of four missions aboard SpaceX, ULA and Orbital-ATK rockets.
Wiese earned his bachelor’s degree in aerospace engineering from Florida Tech in 2000 and his master’s degree in industrial engineering, with a focus on program and project management, from the University of Central Florida in 2011. Wiese was raised in Garrison, New York, and now resides in New Smyrna Beach, Florida, with his wife and three children.https://commons.erau.edu/space-congress-bios-2019/1040/thumbnail.jp
Mark D. Redmond
No full textMarquette University alumnus Mark D. Redmond '76, who received the College of Business Administration's Entrepreneurial Award in 2004
Effects of Moritella viscosa antigens on pro-inflammatory gene expression in an Atlantic salmon (Salmo salar Linnaeus) cell line (SHK-1)
No full textMoritella viscosa is the causative agent of winter ulcer disease in salmonids reared in North-Atlantic countries. In this study the effects of selected M. viscosa antigens on cytotoxicity and pro-inflammatory gene expression in an Atlantic salmon (Salmo salar Linnaeus) macrophage-like cell line (SHK-1) were examined. SHK-1 cells were stimulated with live and heat-killed bacterial cells, extracellular products (ECP) and an extracellular vibriolysin, termed MvP1. Following incubation, cytotoxicity and expression levels of interleukin-1β (IL-1β) and interleukin-8 (IL-8) were examined at different time points. Both live M. viscosa cells and ECP were cytotoxic, but neither heat-killed cells, nor the MvP1 peptidase caused cell death. Expression levels of both IL-1β and IL-8 increased significantly after stimulation with live cells, but heat-killed cells only caused increased IL-8 expression. ECP did not affect IL-1β expression, but did stimulate IL-8 expression. The isolated MvP1 peptidase stimulated both IL-1β and IL-8 expression at the highest concentration tested. This study reveals a difference in the induction of pro-inflammatory gene expression in salmon SHK-1 cells between live and heat-killed M. viscosa cells, and also that an unknown secreted factor is the main stimulant of IL-β and IL-8 expression.ID: S1050464809000990; M3: Article; Accession Number: S1050464809000990; Author: Bryndis Bjornsdottir (a, b); Author: Mark D. Fast (b, 1); Author: Sandra A. Sperker (b); Author: Laura L. Brown (b, 2); Author: Bjarnheidur K. Gudmundsdottir (a, ∗); Affiliation: Institute for Experimental Pathology, University of Iceland, Keldur v/Vesturlandsveg, 112 Reykjavík, Iceland; Affiliation: National Research Council Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, Nova Scotia B3H 2Z1, Canada; Keyword: Moritella viscosa; Keyword: Extracellular products; Keyword: MvP1 vibriolysin; Keyword: Atlantic salmon; Keyword: SHK-1; Keyword: Gene expression; Keyword: Immune response; Keyword: Pro-inflammatory cytokine; Keyword: Interleukin-1β (IL-1β); Keyword: Interleukin-8 (IL-8); Number of Pages: 6; Language: English;Source type: Electronic(1
Privacy vs security
No full textSecuring privacy in the current environment is one of the great challenges of today’s democracies. Privacy vs. Security explores the issues of privacy and security and their complicated interplay, from a legal and a technical point of view. Sophie Stalla-Bourdillon provides a thorough account of the legal underpinnings of the European approach to privacy and examines their implementation through privacy, data protection and data retention laws. Joshua Philips and Mark D. Ryan focus on the technological aspects of privacy, in particular, on today’s attacks on privacy by the simple use of today’s technology, like web services and e-payment technologies and by State-level surveillance activities
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