1,720,958 research outputs found
Diagnosis, antenatal surveillance and management of prolonged pregnancy: Current perspectives
No full textProlonged pregnancy is defined as a pregnancy that extends beyond 42 weeks of gestation (294 days) from the first day of the last normal menstrual period. An accurate estimation of the ‘natural’ incidence of prolonged pregnancy would require meticulous early pregnancy dating. The use of ultrasound to establish gestational age reduces the number of pregnancies that are classified as prolonged. Prolonged pregnancy is associated with an increased perinatal mortality and morbidity in pregnancies which appear to be otherwise low risk. Postterm births are easily preventable by intervening to deliver with the use of induction of labor. Thus, this potentially problematic condition deserves further attention and careful consideration. The focus of this article is to review and challenge some current concepts surrounding the diagnosis and management of prolonged pregnancy. We outline how to identify those women with prolonged pregnancy and which is the appropriate moment to start monitoring the fetal wellbeing. Finally we address the question of benefits and hazards of induction of labor strategies
Intrafollicular nerve growth factor concentration in patients with polycystic ovary syndrome: A case-control study
No full textBACKGROUND: To evaluate the concentration of nerve growth factor (NGF) in follicular fluid of women affected by polycystic ovary syndrome (PCOS) undergoing to In Vitro Fertilization cycle. Methods: In the context of an in-vivo study, a sample of 52 women was considered: 20 were without pathology (male infertility - control group) and 32 were affected by PCOS. All patients received a long stimulation protocol and the oocytes obtained by pick-up were fertilized with standard procedures of intracytoplasmic sperm injection (ICSI). Samples of follicular fluid (FF) were collected at oocyte pick-up. After centrifugation at 560 × g for 3 min, follicular fluid samples were frozen at-80 °C. After thawing the values of NGF in FF were determined by enzyme immunoassay ELISA using commercially available NGF enzyme-linked immunosorbent assay kits. The results of study were analyzed statistically with Student's t-Test. Results: The content of NGF was higher in FF of PCOS patients (2023.30±587.09 pg/mL) in comparison with control group (1704.09±326.8 pg/mL; P<0.05). The levels of serum estrogen (E2) were higher in patients with PCOS (1724.24±635.79 pg/mL) than in control group (1305.3±298.12 pg/mL; P<0.05). The number of retrieved oocytes was more in PCOS patients (9.7±4.6) than in control group (8±4.4), but oocytes in metaphase II were similar in two groups (6.2±2.4 vs. 6.09±4). ConclusionS: The present results show that ovaries of PCOS patients produce more NGF than non-PCOS patients; it confirms that an excess of ovarian NGF might be an abnormality contributing to polycistic ovary morphology and PCOS
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
P16INK4a as a progression/regression tumour marker in LSIL cervix lesions: Our clinical experience
Get PDFPurpose of investigation: The aim of this prospective study was the evaluation of low-grade intraepithelial lesion (LSIL) lesions evolvement in woman with evidence of high risk HPV infection and p16 INK4a negative expression. Materials and Methods: 150 women with cytological diagnosis of LSIL were selected to be underwent to three years of follow-up consisting in smear test, colposcopy, and protein p16 INK4a investigation every six months and HPV-test every 12 months. Result: Final follow-up showed 45 cases of spontaneous lesion regression and 42 cases of persistence with absence of protein p16 INK4a in all of them. There were three cases of disease progression to CIN2, two at 18-month follow-up and one at last follow-up. Disease progression was characterized of p16 INK4a expression. Conclusion: p16 INK4a should help to identify which LSIL cases are inclined to the progression of the disease and focalize which patients are eligible for specific treatment
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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