1,721,006 research outputs found
sj-docx-1-aut-10.1177_13623613221082710 – Supplemental material for A randomized controlled trial into the effects of probiotics on electroencephalography in preschoolers with autism
Supplemental material, sj-docx-1-aut-10.1177_13623613221082710 for A randomized controlled trial into the effects of probiotics on electroencephalography in preschoolers with autism by Lucia Billeci, Alejandro Luis Callara, Letizia Guiducci, Margherita Prosperi, Maria Aurora Morales, Sara Calderoni, Filippo Muratori and Elisa Santocchi in Autism</p
Bleomycin in the setting of lung fibrosis induction: from biological mechanisms to counteractions.
Bleomycin (BLM) is a drug used to treat different types of neoplasms. BLM’s most severe adverse effect
is lung toxicity, which induces remodeling of lung architecture and loss of pulmonary function, rapidly
leading to death. While its clinical role as an anticancer agent is limited, its use in experimental settings
is widespread since BLM is one of the most widely used drugs for inducing lung fibrosis in animals,
due to its ability to provoke a histologic lung pattern similar to that described in patients undergoing
chemotherapy. This pattern is characterized by patchy parenchymal inflammation, epithelial cell injury
with reactive hyperplasia, epithelial–mesenchymal transition, activation and differentiation of fibroblasts
to myofibroblasts, basement membrane and alveolar epithelium injuries. Several studies have demonstrated
that BLM damage is mediated by DNA strand scission producing single- or double-strand breaks
that lead to increased production of free radicals. Up to now, the mechanisms involved in the development
of pulmonary fibrosis have not been fully understood; several studies have analyzed various
potential biological molecular factors, such as transforming growth factor beta 1, tumor necrosis factor
alpha, components of the extracellular matrix, chaperones, interleukins and chemokines. The aim of this
paper is to review the specific characteristics of BLM-induced lung fibrosis in different animal models
and to summarize modalities and timing of in vivo drug administration. Understanding the mechanisms
of BLM-induced lung fibrosis and of commonly used therapies for counteracting fibrosis provides an
opportunity for translating potential molecular targets from animal models to the clinical arena
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
Author-wise bibliometric analysis based on entropy.</p
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