64 research outputs found
Attitudes and Discourse: Spanish Practitioners’ and Undergraduates’ Survey Results
No full textThe emergence of English as the international language of communication has increased the attention and concern given its teaching and learning. This survey-based study explores the attitudes of Spanish practitioners and undergraduate students towards English as the vehicular language in the field of medicine and towards Medical Electronic Popularizations as an alternative to medical research articles. The survey results point out that these subjects’ perception of English as the vehicle of communication in the medical field and their conceptualization of medical electronic popularizations are positive. Pedagogical implications can be drawn from this study since it confirms our students’ awareness of the use of English and the new-born genres or communication channels
ASSESSMENT OF HYBRID SOLAR-THERMAL AND PV SYSTEMS FOR DOMESTIC HEATING AND POWER
No full textImperial Users onl
Raising awareness around writers' voice in academic discourse : an analysis of writers' (in)visibility
No full textThis paper aims to contribute to the study of the concept of writer's visibility inspired by approaches to the analysis of identity in written discourse (see Ivanic 1998, Charles 1999 and John 2005). The way medical academic writers selfrepresent themselves in their research articles can be seen in terms of a gradable visibility cline crafted and constrained by the academic genre expectations of these texts (Swales and Feak 2004; Stock and Eik-Nes 2016). Traditionally, authorial visibility has been studied within frameworks such as evaluation, authorial voice and stance. Still, there is no framework as yet been proposed that binds together possible textual realisations that can be considered as visibility features in academic written texts. This paper conducts a study of 40 medical research articles that reveal different manifestations of the authors' presence. A cline is proposed that encompasses different lexico-grammatical realisations such as self-mentions, passive constructions and non-animated subjects followed by active verbs. These features can be interpreted as authorial voice realisations that allow us to measure or grade writers' visibility and its rhetorical implication in the text
An optimized method for the extraction of ancient eukaryote DNA from marine sediments
No full textMarine sedimentary ancient DNA (sedaDNA) provides a powerful means to reconstruct marine palaeo-communities across the food web. However, currently there are few optimized sedaDNA extraction protocols available to maximize the yield of small DNA fragments typical of ancient DNA (aDNA) across a broad diversity of eukaryotes. We compared seven combinations of sedaDNA extraction treatments and sequencing library preparations using marine sediments collected at a water depth of 104 m off Maria Island, Tasmania, in 2018. These seven methods contrasted frozen versus refrigerated sediment, bead-beating induced cell lysis versus ethylenediaminetetraacetic acid (EDTA) incubation, DNA binding in silica spin columns versus in silica-solution, diluted versus undiluted DNA in shotgun library preparations to test potential inhibition issues during amplification steps, and size-selection of low molecular-weight (LMW) DNA to increase the extraction efficiency of sedaDNA. Maximum efficiency was obtained from frozen sediments subjected to a combination of EDTA incubation and bead-beating, DNA binding in silica-solution, and undiluted DNA in shotgun libraries, across 45 marine eukaryotic taxa. We present an optimized extraction protocol integrating these steps, with an optional post-library LMW size-selection step to retain DNA fragments of ≤500 base pairs. We also describe a stringent bioinformatic filtering approach for metagenomic data and provide a comprehensive list of contaminants as a reference for future sedaDNA studies. The new extraction and data-processing protocol should improve quantitative paleo-monitoring of eukaryotes from marine sediments, as well as other studies relying on the detection of highly fragmented and degraded eukaryote DNA in sediments.Linda Armbrecht, Salvador Herrando-Pérez, Raphael Eisenhofer, Gustaaf M. Hallegraeff, Christopher J. S. Bolch, Alan Coope
Restoration of 19th Century oil on canvas.Portrait of magistrate joseph bernard falquet (1776 – 1836) by the french painter jacques guille (1814 – 1873) .
No full text[ES] Este Trabajo de Fin de Grado en Conservación y Restauración de Bienes Culturales (Universidad Politécnica de Valencia, España) se centra en un retrato al óleo sobre lienzo de la Francia del siglo XIX. El proyecto se ha realizado gracias a una estancia de prácticas en la empresa australiana Artlab, en dos fases de trabajo: (1) una investigación sistemática sobre la procedencia del retrato, y (2) y la concepción e implementación de un protocolo de restauración de la obra.
La pintura carecía de firma, y presentaba una nota escrita a mano, en el reverso del bastidor, que indicaba que el retrato representaba a un varón adulto de la familia Falquet de la localidad francesa de Chambery (Saboya, Francia). En base a la literatura primaria y comunicaciones con expertos, se llegó a la conclusión de que el teatro fue creado por Jacques Guille (artista francés especializado en pintura religiosa), y el hombre retratado era el Barón Joseph Bernard Falquet (magistrado que ocupó importantes cargos institucionales en la región de Saboya en tiempos posteriores a Napoleón). El estilo del retrato se encuadra dentro de la corriente neoclásica.
En general, la obra se encontraba en mal estado de conservación. El soporte textil presentaba un desgarro en la esquina inferior izquierda, se localizaron pérdidas de estrato pictórico en los bordes, y la superficie pintada estaba cubierta de suciedad superficial. Además, se identificaron zonas con abundante repinte como resultado de una intervención previa que había rellenado con estuco varios agujeros en el textil del lienzo.
La obra fue analizada mediante fotografía y reflectografía, y la intervención adoptó los protocolos establecidos por Artlab con los principales objetivos de realzar la estabilidad de la obra con un nuevo bastidor, restablecer la integridad del soporte textil, eliminar los parches de la vieja restauración, restaurar los estratos pictóricos y dotar a la pintura de protección para preservarla en el futuro.
La ejecución del proyecto se enriqueció por la interacción con procedimientos modernos de restauración dentro de un equipo profesional, y porque pudo contrastarse la formación teórica adquirida durante la licenciatura con la práctica de completar de principio a fin la restauración de una obra de arte.[EN] This Final-Year Project of the Bachelor¿s Degree in Conservation and Restoration of Cultural Heritage (University of Valencia, Spain) focuses on an easel oil-on-canvas portrait from 19th Century France. The project has been undertaken through an internship with ArtLab Australia, and consists of (1) a research component to identify the provenance of the portrait, and (2) a technical component to elaborate and implement a protocol of restoration.
The painting lacked author signature, and had a hand-written annotation on the backside of the stretcher indicating that the painted character was an adult male with the surname Falquet from the town of Chambery (Savoy, France). Based on a review of the primary literature and personal communications with international experts, it was concluded that the portrait was painted by Jacques Guille (a French artist who specialized in religious paintings), and the portrayed man was Baron Joseph Bernard Falquet (a French magistrate who played important institutional roles in post-Napoleon Savoy). The style of the portrait falls in the range of neoclassicism and realism.
Overall, the portrait was in poor condition. The canvas had a tear in the lower-left corner and had lost paint layers mostly along its edges, and the pictorial surface was entirely covered with superficial dirt. Repainted areas from a previous intervention were found over a stucco that filled several holes in the fabric of the canvas.
The restoration protocol applied to the portrait was based on photographic and reflectographic analyses and followed Artlab¿s canonical procedures with the major goals of enhancing structural stability with a new stretcher, re-establishing canvas integrity, removing old-restoration patches, restoring the paint layers and providing protection for long-term preservation.
Throughout, the project benefited from the exposure to the modus operandi of a professional team and from contrasting the theoretical fundaments provided by a Bachelor¿s Degree with the true process of restoration of a piece of art.José Herrando, C. (2021). Restoration of 19th Century oil on canvas.Portrait of magistrate joseph bernard falquet (1776 – 1836) by the french painter jacques guille (1814 – 1873) . Universitat Politècnica de València. https://riunet.upv.es/handle/10251/173268TFG
Assisting language learning with new technologies: A case of Spanish degrees facing European educational change process
No full textOne of the biggest challenges European countries have lately faced is The Bologna Process which consists of a series of ministerial agreements between European countries designed to ensure comparability in the standards and quality of higher education qualifications. The resulting European Higher Education Area (EHEA) propelled a sudden implementation of a new organizational approach into the Spanish academic system in 2008. This paper traces the evolution of lectures in English for Specific Purposes (ESP) over three semesters in this changing teaching environment in the Health Science and Medicine Faculties of the University of Zaragoza (Spain). The aim of this paper is to assess the value, among students, of the use of social media and virtual tools in a strictly academic context. The implementation of change in instructional design was necessary due to the limitations in the existing teaching practices. Consequently, the teacher’s and students’ experiences over each of the three semesters led to the implementation of Microsoft MSN Messenger, a course blog and a Facebook profile. Data from this contribution to action research suggest that students’ opinions and perceptions of the use of personally oriented technology in the language learning process were positive in my university academic context
Eugenio d’Ors y Simone Weil: impacto en Aranguren
No full textEugenio d’Ors is the first author to write about Simone Weil in Spain. He does it in May 1949, recalling Gustave Thibon, one of the speakers of the summer courses held in Santander in August 1948. Thibon, to whom the French philosopher had entrusted part of her writings, published a selection of them in 1948, and Eugenio d’Ors, always attentive to what aroused interest outside of Spain, gives his impressions about the book. A little later, in 1951, it will be José Luis L. Aranguren, surely alerted by his teacher, who is interested in Weil’s work in that same vein to make Spanish readers participate in the thought in vogue in Europe. But Aranguren, who feels challenged by the work of Simone Weil, dwells more on it and frames it in the reality of the present, wondering how the man of his time relates to God.Eugenio d’Ors es el primer autor que en España escribe sobre Simone Weil. Lo hace en una glosa de mayo de 1949, recordando a Gustave Thibon, uno de los profesores de los cursos de verano celebrados en Santander en agosto de 1948. Thibon, a quien la filósofa francesa había confiado parte de sus escritos, publicó una selección de ellos en 1948, y Eugenio d’Ors, siempre atento a lo que despertaba interés fuera de España, da sus impresiones acerca del libro. Poco más tarde, en 1951, será José Luis L. Aranguren, alertado seguramente por su maestro, quien se interese por la obra de Weil en ese mismo empeño por hacer partícipes a los lectores en español del pensamiento que estaba en boga en Europa. Pero Aranguren, que se siente interpelado por la obra de Simone Weil, se detiene más en ella y la enmarca en la realidad del presente preguntándose cómo se relaciona con Dios el hombre de su tiempo
Eugenio d’Ors y Simone Weil: impacto en Aranguren
No full textEugenio d’Ors is the first author to write about Simone Weil in Spain. He does it in May 1949, recalling Gustave Thibon, one of the speakers of the summer courses held in Santander in August 1948. Thibon, to whom the French philosopher had entrusted part of her writings, published a selection of them in 1948, and Eugenio d’Ors, always attentive to what aroused interest outside of Spain, gives his impressions about the book. A little later, in 1951, it will be José Luis L. Aranguren, surely alerted by his teacher, who is interested in Weil’s work in that same vein to make Spanish readers participate in the thought in vogue in Europe. But Aranguren, who feels challenged by the work of Simone Weil, dwells more on it and frames it in the reality of the present, wondering how the man of his time relates to God.Eugenio d’Ors es el primer autor que en España escribe sobre Simone Weil. Lo hace en una glosa de mayo de 1949, recordando a Gustave Thibon, uno de los profesores de los cursos de verano celebrados en Santander en agosto de 1948. Thibon, a quien la filósofa francesa había confiado parte de sus escritos, publicó una selección de ellos en 1948, y Eugenio d’Ors, siempre atento a lo que despertaba interés fuera de España, da sus impresiones acerca del libro. Poco más tarde, en 1951, será José Luis L. Aranguren, alertado seguramente por su maestro, quien se interese por la obra de Weil en ese mismo empeño por hacer partícipes a los lectores en español del pensamiento que estaba en boga en Europa. Pero Aranguren, que se siente interpelado por la obra de Simone Weil, se detiene más en ella y la enmarca en la realidad del presente preguntándose cómo se relaciona con Dios el hombre de su tiempo
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No full textThe subtribe Saussureinae is a highly speciose group with more than 600 species distributed in the Northern Hemisphere and is particularly species-rich at the high mountains of central and eastern Asia. Saussurea and Jurinea are the two main genera described within the subtribe. However, up to 15 satellite genera are recognized in some recent taxonomic treatments with an analytical viewpoint. For the first time, we carried out a complete sampling to clarify generic boundaries based on a well-resolved phylogeny of Saussureinae. We employed a Hyb-Seq technique that targets 1061 nuclear conserved ortholog loci designed for Compositae. After a filtering of potential paralogs, 588 loci were retained to infer phylogenetic trees under concatenation and coalescence approaches. High branch support resolution was recovered at the generic level, but a non-monophyletic pattern was detected for most of the genera as they are currently circumscribed. Accordingly, we propose a new generic delimitation based on the three main clades recovered in the backbone tree, which are also in agreement with morphological evidence: Dolomiaea, Saussurea, and Jurinea. Following this classification into three genera, 18 new combinations are proposed. This new genus delineation will be used as a basis for future evolutionary studies in the Saussureinae.Financial support from the Ministerio de Ciencia e Innovación (Project CGL2015-66703-P MINECO/FEDER, UE and Ph.D. grant to Sonia Herrando-Moraira) and the Catalan government (“Ajuts a grups consolidats” 2017-SGR1116) is also greatly acknowledged. This study has been performed under the Ph.D. program “Plant Biology and Biotechnology” of the Autonomous University of Barcelona (UAB)INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
TAXONOMIC IMPLICATIONS
NOTE ADDED IN PROOF
AUTHOR CONTRIBUTIONS
ACKNOWLEDGMENT
Hereditary Cancer Program (ProCanHe): 21-years of experience at a referral registry in Argentina
No full textRegistries in South America were initiated in the early 90´s with thehelp of Henry T. Lynch. The Programa de Cancer Hereditario (Pro.Can.He), is a multidisciplinary program established in 1996 at theHospital Italiano, Argentina. The aim of the study is to update our 21-year experience to determine the applicability of genetic testshighlighting the most informative molecular findings in relation toLynch syndrome mostly.Materials and methods: Families undergoing genetic testing aftergenetic counselling between1996-2018 were included. Data were obtainedfrom a prospective IRB approved database. Clinicalepidemiologicaland molecular variables were analysed. Genetic testswere carried out after a genetic counselling session and obtainingthe informed consent of the patient.Molecular testingUntil 2015, the search for variants was carried out by PCR and Sangersequencing of exons and adjacent intronic regions of MLH1 andMSH2. Then, sequencing of MLH1/MSH2/MSH6/PMS2/EPCAM geneswas performed by NGS and large rearrangements were detected byMLPA. The variants were classified according to international databases.Variants with uncertain or unreported clinical significancewere analysed In-silico using the PolyPhen, SIFT and/or Human Splicingfinder 3.0 software.ResultsA total of 83 families (49 fulfilled Amsterdam Criteria [AC] and 34 BethesdaCriteria [BC]) were analysed. Pathogenic variants were foundin 26 out of 83 (31.3%) families, been 23 pathogenic and 3 likelypathogenic.Splice site and large rearrangements represented 19.2% (5/26) and11.5% (3/26) of the variants.23% (6/26) of them were originally describedin this series and 1 was a founding mutation from Piedmont,Italy. Affected genes include MSH2, MLH1, MSH6 and PMS2 (12, 11, 2and 1 cases respectively). Mutation detection rates in AC and BT familieswere 48.9% (N=24) and 5.9% (N=2), p<0.01. Among AC families,those with identified mutation had a lower median age of cancer onset and higher incidence of extra-CCR cancer than those withoutidentified mutations. Additionally, we have also studied other genesin patients with different clinical conditions included in the registry.We identified mutations in APC, MUTYH, BMPR1A, SMAD4, CDH1,BRCA1-2, CHEK2.ConclusionThe multidisciplinary approach and the international collaborationsallowed the correct implementation of the genetic tests. To ourknowledge, this study is the first Characterization of AC families accordingto genetic tests in South America. This allowed the identificationof AC families with different ages of onset and prevalence ofextra-CRC cancers, as well as several significant variant not previouslyreported in international databases.Fil: Piñero, Tamara Alejandra. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Houssay. Instituto de Medicina Traslacional E Ingenieria Biomedica. - Hospital Italiano. Instituto de Medicina Traslacional E Ingenieria Biomedica. - Instituto Universitario Hospital Italiano de Buenos Aires. Instituto de Medicina Traslacional E Ingenieria Biomedica.; ArgentinaFil: Herrando, Ignacio. Hospital Italiano; ArgentinaFil: Kalfayan, Pablo Germán. Hospital Italiano; ArgentinaFil: Gonzales, M.. Hospital Italiano; ArgentinaFil: Ferro, A.. Hospital Italiano; ArgentinaFil: Santino, Juan Pablo. Hospital Italiano; ArgentinaFil: Cajal, R.. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Houssay. Instituto de Medicina Traslacional E Ingenieria Biomedica. - Hospital Italiano. Instituto de Medicina Traslacional E Ingenieria Biomedica. - Instituto Universitario Hospital Italiano de Buenos Aires. Instituto de Medicina Traslacional E Ingenieria Biomedica.; ArgentinaFil: Falconi, D.. Hospital Italiano; ArgentinaFil: Guerrero, Gisella. Hospital Italiano; ArgentinaFil: Verzura, A.. Hospital Italiano; ArgentinaFil: Riggi, Maria. Hospital Italiano; ArgentinaFil: Church, James. No especifíca;Fil: Peltomäki, P.. No especifíca;Fil: Martins, Alexandra. No especifíca;Fil: Pavicic, Walter Hernan. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Houssay. Instituto de Medicina Traslacional E Ingenieria Biomedica. - Hospital Italiano. Instituto de Medicina Traslacional E Ingenieria Biomedica. - Instituto Universitario Hospital Italiano de Buenos Aires. Instituto de Medicina Traslacional E Ingenieria Biomedica.; ArgentinaFil: Dominguez, M.. University of Oslo; NoruegaFil: Vaccaro, C.. Hospital Italiano; ArgentinaThe 3rd European Hereditary Tumour Group MeetingNiceFranciaEuropean Hereditary Tumour Group Meetin
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