162 research outputs found
Corrigendum to “The vicious circle of treatment-induced toxicities in locally advanced head and neck cancer and the impact on treatment intensity” [Crit. Rev. Oncol./Hematol. 116 (2017) 82–88]
No full textThe authors regret that the names and surnames did not appear in the correct order. These should appear as: Paolo BossiaMaria Cossu RoccabRenzo CorvÃ2cRoberta DepennidVittorio GuardamagnaeFranco MarinangelifFrancesco Miccichà ̈gFabio TrippahThe authors would like to apologise for any inconvenience caused
A case of primary hydatidosis of the thyroid gland
No full textA 54-year-old woman presented with an expansive mass in the anterior cervical region (front of the neck) with abscess. Laboratory tests and thyroid profile proved normal. Surgical exploration revealed a hydatid cyst in the left lobe of the thyroid gland with parasitic metastasis of the left lateral cervical lymph node chain. Postoperative examination of the nodule showed it to be a solitary primary thyroid hydatid cyst.A 54-year-old woman presented with an expansive mass in the anterior cervical region (front of the neck) with abscess. Laboratory tests and thyroid profile proved normal. Surgical exploration revealed a hydatid cyst in the left lobe of the thyroid gland with parasitic metastasis of the left lateral cervical lymph node chain. Postoperative examination of the nodule showed it to be a solitary primary thyroid hydatid cyst
A case of primary hydatidosis of the thyroid gland
No full textA 54-year-old woman presented with an expansive mass in the anterior cervical region (front of the neck) with abscess. Laboratory tests and thyroid profile proved normal. Surgical exploration revealed a hydatid cyst in the left lobe of the thyroid gland with parasitic metastasis of the left lateral cervical lymph node chain. Postoperative examination of the nodule showed it to be a solitary primary thyroid hydatid cyst.A 54-year-old woman presented with an expansive mass in the anterior cervical region (front of the neck) with abscess. Laboratory tests and thyroid profile proved normal. Surgical exploration revealed a hydatid cyst in the left lobe of the thyroid gland with parasitic metastasis of the left lateral cervical lymph node chain. Postoperative examination of the nodule showed it to be a solitary primary thyroid hydatid cyst
Role of CT perfusion in monitoring and prediction of response to therapy of head and neck squamous cell carcinoma
No full textThis review aims to summarize the technique and clinical applications of CT perfusion (CTp) of head and neck cancer. The most common pathologic type (90%) of head and neck cancer is squamous cell carcinoma (HNSCC): its diagnostic workup relies on CT and MRI, as they provide an accurate staging for the disease by determining tumour volume, assessing its extension, and detecting of lymph node metastases. Compared with conventional CT and MRI, CTp allows for obtaining measures of tumour vascular physiology and functional behaviour, and it has been demonstrated to be a feasible and useful tool in predicting local outcomes in patients undergoing radiation therapy and chemotherapy and may help monitor both treatments
HPV infection and triple-negative breast cancers: an Italian case-control study
No full textBackground: Breast cancer is one of the most important neoplasia among women. To reduce its incidence and
mortality impact it would be desirable to early identify risk factors associated with its development. It was recently suggested that biological agents could be the etiological cause, particularly Human Papilloma Virus (HPV). No specific relationship with different breast cancer types has been demonstrated until now. In particular, the triple-negative breast cancer (TNBC), characterized by a receptor negative pattern (ER/PgR/HER2–negative) and poor prognosis, can represent one of the most relevant clinical and public health priority in terms of observational research.
Findings: Aim of the study was to evaluate the HPV-positivity prevalence in two breast cancer series (TNBC
vs. non-TNBC) in Northern Sardinia, Italy. The sample size of each group was represented by 40 formalin-fixed
and paraffin-embedded specimens. The mean age was 60.3 years. The majority of the cancers were ductal
(84%). The grading distribution was different: G2 was the most prevalent grade in the non-TNBC series, whereas
G3 was the most frequent in the TNBC series (70% and 72%, respectively). Six biological samples were HPV-positive
(7.5%): the positivity was assessed only in the TNBC group (15%; p-value: 0.026). The isolated genotypes were: 16, 31,
45, 52, 6, and 66. Only one co-infection was found (i.e., HPV-6 and -66).
Conclusions: The prevalence of HPV-positivity in TNBC specimens was 15%. On the basis of its carcinogenetic ability, an etiological role in the pathogenesis of the cancer could be supposed. This association should be confirmed with longitudinal studies to better assess the role of the HPV infection in TNBC and non-TNBC tumors
Impiego della mucosa labiale nella realizzazione di una cistostomia continente e cateterizzabile
No full textThe vicious circle of treatment-induced toxicities in locally advanced head and neck cancer and the impact on treatment intensity
No full textThe intensity of the available treatment approaches for locally-advanced head and neck cancer (HNC) is at the upper limit of tolerance of acute toxicities. Several factors including breakthrough cancer pain, mucositis, dysphagia, local and systemic infections, and nutritional problems are related to treatment intensity. Particularly, pain, as symptom directly associated with the disease or combined with other treatment-related factors, has a major impact on quality of life of HNC patients and ultimately can influence the efficacy of treatments in HNC. Here, a Multidisciplinary Board of Italian Experts has addressed these issues, with the aim to identify the unmet need and appropriate strategies for the maintenance of optimal treatment intensity in HNC
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