1,721,085 research outputs found
Systemic photoimmunoprotection: a combine approach of PDT (Photo Dynamic therapy) – Polypodium Leucotomos extract in the treatment of scalp AKs
No full textInfections in Patients with Atopic Dermatitis and the Infuence of Treatment
Full text linkAtopic dermatitis (AD) is a T helper 2-mediated chronic infammatory skin disease that afects children and adults. Patients
with AD are prone to recurrent infections of the skin and other organs, which can severely worsen the disease course. This
review summarises the current evidence on the aetiology, pathogenesis, treatment and prevention of infections in patients
with AD. PubMed was searched for English-language research articles, systematic reviews, meta-analyses and guidelines
published until February 2023 using the key term “atopic dermatitis” and terms relevant to infections. Patients with AD
have an increased risk of bacterial, viral and fungal infections of the skin, mainly due to impaired barrier function, altered
immune response and frequent scratching. The most common pathogens are Staphylococcus aureus and herpes simplex
virus, which can cause impetigo, folliculitis, abscesses, eczema herpeticum and other complications. They also appear to
increase susceptibility to systemic infections, including respiratory and urinary tract infections and sepsis. Certain systemic
treatments for AD, such as mycophenolate mofetil and Janus kinase inhibitors, increase the risk of viral infections. Prevention
and treatment of recurrent infections in patients with AD require a multifaceted approach that includes topical and systemic
antimicrobials, skin care and efective control of AD symptoms (to break the itch–scratch cycle). Preventing and limiting
the development of infections are important considerations in choosing an AD treatment
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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