28 research outputs found
Un caso di abuso di paroxetina
No full textSi descrive caso di epatotossicità da abuso di paroxetina in tentato suicidio. L’epatotossicità con caratteristica di epatite eosinofila è un raro evento durante terapia con paroxetina. Può avvenire nel contesto di overdose come nel caso descritto ma con una prognosi comunque favorevole. Il meccanismo di danno epatocellulare sembra essere un effetto idiosincrasico dose-dipendente. Il trattamento consiste nella sospensione del farmaco. Il possibile effetto positivo nell’N-acetilcisteina non è documentato in letteratura
Incidental discovery of testicular microlithiasis: What is the importance of ultrasound surveillance? Two case reports
No full textMany studies have demonstrated an association between diffuse bilateral testicular microlithiasis (TM) and gonadal and extragonadal germ cell tumors. Nevertheless, it is still uncertain whether ultrasound surveillance is really necessary in patients with TM in the absence of other risk factors such as previous testicular cancer, a history of cryptorchidism or testicular atrophy. We report the cases of a 33- and a 39-year-old man presenting with a retroperitoneal extragonadal tumor. The first patient underwent an MRI examination in order to rule out a lumbosacral hernia: MRI images showed no slipped disks but a voluminous retroperitoneal solid mass. The histological analysis revealed an immature teratoma. The second patient came to the emergency department complaining of abdominal pain, vomiting, weight loss and mild jaundice: ultrasound examination showed a large, ill-defined heterogeneous abdominal mass, confirmed by CT and MRI examination. The histology diagnosed a yolk sac tumor. In both patients, the testicular sonography was performed to rule out a focal lesion, but it displayed bilateral TM without a focal testicular mass. Based on our direct experience, we highlight the importance of annual ultrasonographic surveillance of the testis and the retroperitoneal space in patients with occasionally detected TM
Evaluation of early myocardial damage in systemic sclerosis (SSc): a cardiovascular magnetic resonance study
No full textNoncompaction Cardiomyopathy: Left Ventricular Systolic Dysfunction is not Correlated to Non-compacted Myocardium Extent on Cardiac Magnetic Resonance
No full textCaractérisation de distillats de marcs espagnols "Orujo de Galice" par analyse d'isotopes stables
No full textIl ruolo della TEM nel trattamento dei tumori del retto extraperitoneale
No full textAfter Heald's revolution in 1982, who introduced the Total Mesorectal Excision, for improve the results in terms of recurrance and survival rate, there is a need to explore new therapeutic options in treatment of sub-peritoneal rectal cancer. In particular, local excision represent more often a valid technique for non advanced rectal cancer treatment in comparison with the more invasive procedure, especially in elderly and/or in poor health patients. The introduction of TEM by Buess (Transanal endoscopy Microsurgery), has extended the local treatment also to classes of patients who would normally have been candidates for TME. The author gives literature's details and his experience in the use of TEM for early rectal cancer sub-peritoneal. The aim of the study is to analyze short and long term results in terms of local recurrence and survival rate comparing TEM technique with the other transanal surgery in rectal cancer treatment. Preoperative Chemio-Radio therapy and rigorous Imaging Staging are the first steps to planning surgery. It's time, for local rectal cancer, has come to make the devolution a few decades ago has been accomplished in the treatment of breast cancer
A new device for ultrasound-guided peripheral venous access
No full textBackground: In patients with difficult peripheral venous access, alternative techniques require expertise and are invasive, expensive, and prone to serious adverse events. This brought us to designing a new venous catheter (JLB® Deltamed, Inc.) for the cannulation of medium and large bore veins; it is echogenic, and available in different lengths (60 / 70 / 80 mm) and Gauges (14 / 16 / 17 / 18). Methods: We led a multi-center observational convenience sampling study to evaluate safety and effectiveness of JLB. Data was collected from June 2015 to February 2018. Inclusion criteria were age ⩾ 18, difficulty in obtaining superficial venous access in the veins of the arm, need for rapid infusion, or patient’s preference. Results: We enrolled 1000 patients, mean age 66.8 years. In total, 951 (95.1%) had the device placed in internal jugular vein, 28 in basilic or cephalic vein, 15 in femoral vein, 5 in axillary vein (infra-clavicular tract), and 1 in the external jugular vein. The procedure was performed by attending physicians or emergency medicine residents under US guidance. Mean procedure time (from disinfection to securing) was approximately 240 s. Mean attempts number was 1.21. Early complications (<24 h) occurred in four patients, consisting in two soft tissue hematoma, one phlebitis, and one atrial tachyarrhythmia. No major complications (such as pneumothorax) were reported. Mean indwelling time was 168 h (7 days); early occlusion/dislocation occurred in four cases. Conclusion: According to preliminary data, the application of JLB appears to be safe, cost-effective, and rapid to place bedside
Sviluppo ed applicazione di un algoritmo per la pallettizzazione e la saturazione del mezzo di trasporto: il caso Gruppo Montenegro S.r.l. - Food Division
No full textL’elaborato di tesi è frutto di un percorso di tirocinio svolto in Gruppo Montenegro S.r.l., il cui obiettivo risiede nello sviluppo di un algoritmo per la pallettizzazione e la saturazione del mezzo di trasporto per la Divisione Food. Nello specifico viene
proposto un algoritmo euristico elaborato nel linguaggio di programmazione Python.
La divisione Food è costituita da tre categorie: Cannamela, Cuore e Vitalia.Queste comprendono prodotti molto eterogenei. Attraverso il coinvolgimento delle funzioni aziendali di Packaging e Qualità, sono stati stabiliti i vincoli da rispettare per la pallettizzazione dei prodotti.
L’algoritmo proposto viene descritto suddividendo il processo in tre macro-step.
La prima parte affronta il problema del 3D Bin Packing Problem, utilizzando e modificando un programma già presente in letteratura per soddisfare le esigenze della categoria Cannamela. Quest’ultima a differenza delle altre categorie, viene allestita
in groupage preallestito poiché gli ordini Cannamela possono contenere quantità non-multiple rispetto alle quantità contenute nell’imballo secondario.
La seconda parte dell’algoritmo si occupa della creazione dei pallet per le categorie Cuore e Vitalia. Attraverso l’utilizzo dell’algoritmo di clustering K-means sono state create famiglie di codici che permettessero l’allestimento di pallet con prodotti considerati simili. Di conseguenza, l’algoritmo per la pallettizzazione delle
due categorie viene sviluppato ex-novo basandosi sulla percentuale di occupazione del prodotto nel pallet.
L’ultima parte dell’algoritmo studia la possibilità di sovrapporre i pallet precedentemente creati.
Infine, viene effettuata un’analisi di un periodo strategico confrontando i risultatidell’algoritmo Python con quelli dell’algoritmo presente nel gestionale aziendale. I risultati vengono poi analizzati in relazione a due impatti importanti per l’azienda:economici e ambientali
