476 research outputs found

    Retention data

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    Retention data used in publications in or submitted to Journal of Chromatography A with A. R. Horner as first author. Retention data for ~ 100 compounds on a Waters BEH C-18 column in acidic acetonitrile/water mobile phases at phase ratio and temperatures giving a range of k for each compound about 1 - 100. These are in the CSV file "RetentionData". The compounds/solutes are identified by number. The correspondence between the number and the compound name is in "Compound List and Conditions". Enthalpies for the compounds and functional group counts are in FGEnthalpyData.xls

    Horner Syndrome from a Pediatric Otolaryngology Perspective.

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    © The Author(s) 2019. Introduction: Horner syndrome is described as the clinical triad of miosis, ptosis, and anhidrosis. In pediatric patients the condition may be congenital or acquired from neoplastic, infectious or traumatic conditions, including birth trauma. Most cases of pediatric Horner syndrome present first to a pediatric ophthalmologist however since the neural pathways involve the cervical sympathetic chain otolaryngologists should understand the pathophysiology to avoid delay in management of potentially malignant cases. Objectives: To aid otolaryngologists in recognizing and managing pediatric Horner syndrome by describing 3 unique cases from malignant, traumatic and/or congenital causes. Methods: Case report of 3 pediatric patients with Horner syndrome presenting to our pediatric otolaryngology department. Results: Case #1 is 5-month-old female with ptosis and a left level II 1.5 cm neck mass. Magnetic resonance imaging showed the mass displacing the common carotid artery and excisional biopsy revealed a poorly differentiated neuroblastoma. Case #2 is a 9-year-old female with anisocoria appearing after suffering a severe playground injury. Case #3 is a 3-year-old-male who developed ptosis and anisocoria following re-excision of a recurrent cervical lymphatic malformation. Conclusion: Pediatric Horner syndrome may be a benign finding that is easily overlooked but may reflect a serious underlying condition. Otolaryngologists should be aware of the pathophysiology and differential diagnosis, including malignant causes, to appropriately manage patients

    Beiträge zur Ophthalmologie als festgabe Friedrich Horner zur Feier des fünfundzwanzigjährigen Jubiläums seiner academischen Lehrthätigkeit gewidmet

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    BEITRÄGE ZUR OPHTHALMOLOGIE ALS FESTGABE FRIEDRICH HORNER ZUR FEIER DES FÜNFUNDZWANZIGJÄHRIGEN JUBILÄUMS SEINER ACADEMISCHEN LEHRTHÄTIGKEIT GEWIDMET Franciscus Cornelius Donders Library (-) Beiträge zur Ophthalmologie als festgabe Friedrich Horner zur Feier des fünfundzwanzigjährigen Jubiläums seiner academischen Lehrthätigkeit gewidmet (-

    Retention data

    No full text
    Retention data used in publications in or submitted to Journal of Chromatography A with A. R. Horner as first author. Retention data for ~ 100 compounds on a Waters BEH C-18 column in acidic acetonitrile/water mobile phases at phase ratio and temperatures giving a range of k for each compound about 1 - 100

    Reshaping Professionalization: Response to Bruce Horner\u27s \u27Traditions and Professionalization: Reconceiving Work in Composition\u27

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    Author responds to article Horner, Bruce. Traditions and Professionalization: Reconceiving Work in Composition. College Composition and Communication, Vol. 51, No. 3 (Feb., 2000), pp. 366-398. Available at: http://www.jstor.org/stable/35874

    Longus Coli Inflammation as an Uncommon Cause of Horner\u27s Syndrome

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    The oculosympathetic pathway originates in the hypothalamus, descends through the brainstem, exits the cervicothoracic junction, ascends up and over the lung, and along the carotid to the sudomotor fibers of the face, the pupillary dilators, and muller\u27s muscle. Lesions at any point along this chain may cause ptosis, miosis, anhidrosis, classically known as Horner\u27s Syndrome. The longus colli are weak cervical flexor muscles which abut the ascending sympathetic ganglia. Here we present a case of nonspecific longus colli inflammation likely secondary to motor vehicle accident as an uncommon cause of Horner\u27s Syndrome. Longus colli injury during cervical spinal injury as well as a suspected paraspinal mass of the longus colli have both been previously reported. To the author\u27s knowledge, this is the first case of bilateral asymmetric longus colli inflammation causing Horner\u27s syndrome

    Investigations with Monte Carlo Tree Search for finding better multivariate Horner schemes (abstract)

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    After the defeat of the human chess World Champion in 1997, many researchers turned their attention to the oriental game of Go. The minimax approach, so successful in chess, did not work in Go. Instead, around 2006 a new method was developed: MCTS (Monte Carlo Tree Search). The success of MCTS in Go caused researchers to apply the method to other domains. In this article we report on experiments with MCTS for finding improved orderings for multivariate Horner schemes, a basic method for evaluating polynomials. We report on initial results that typically improve existing methods by a factor of two. In addition, we continue with an investigation into two parameters that guide the MCTS search. It will be interesting to see if these insights can be transferred to other domains

    Computational modelling for dry-powder inhalers

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    Computational fluid dynamics (CFD) is a simulation tool used for modelling powder flow through inhalers to allow optimisation both of device design and drug powder. Here, Ralf Kröger, Consulting Senior CFD Engineer, ANSYS Germany GmbH; Marc Horner, Lead Technical Services Engineer, Healthcare, ANSYS, Inc; Robert Woolhouse, Senior CFD Engineer, ANSYS UK, Ltd; Michael Becker, PhD Student, and Herbert Wachtel, Senior Principal Scientist, both of Boehringer Ingelheim Pharma GmbH & Co KG; and Anne De Boer, Research Leader Inhalation, University of Groningen, Groningen, The Netherlands, describe in detail how CFD was used in the optimisation of the TwincerTM dry-powder inhaler, extensions of current particle modelling physics to account for particle-particle interactions, and the benefits of this approach in product development. © 2012 Frederick Furness Publishing

    Computational modelling for dry-powder inhalers

    No full text
    Computational fluid dynamics (CFD) is a simulation tool used for modelling powder flow through inhalers to allow optimisation both of device design and drug powder. Here, Ralf Kröger, Consulting Senior CFD Engineer, ANSYS Germany GmbH; Marc Horner, Lead Technical Services Engineer, Healthcare, ANSYS, Inc; Robert Woolhouse, Senior CFD Engineer, ANSYS UK, Ltd; Michael Becker, PhD Student, and Herbert Wachtel, Senior Principal Scientist, both of Boehringer Ingelheim Pharma GmbH & Co KG; and Anne De Boer, Research Leader Inhalation, University of Groningen, Groningen, The Netherlands, describe in detail how CFD was used in the optimisation of the TwincerTM dry-powder inhaler, extensions of current particle modelling physics to account for particle-particle interactions, and the benefits of this approach in product development. © 2012 Frederick Furness Publishing

    Computational modelling for dry-powder inhalers

    No full text
    Computational fluid dynamics (CFD) is a simulation tool used for modelling powder flow through inhalers to allow optimisation both of device design and drug powder. Here, Ralf Kröger, Consulting Senior CFD Engineer, ANSYS Germany GmbH; Marc Horner, Lead Technical Services Engineer, Healthcare, ANSYS, Inc; Robert Woolhouse, Senior CFD Engineer, ANSYS UK, Ltd; Michael Becker, PhD Student, and Herbert Wachtel, Senior Principal Scientist, both of Boehringer Ingelheim Pharma GmbH & Co KG; and Anne De Boer, Research Leader Inhalation, University of Groningen, Groningen, The Netherlands, describe in detail how CFD was used in the optimisation of the TwincerTM dry-powder inhaler, extensions of current particle modelling physics to account for particle-particle interactions, and the benefits of this approach in product development. © 2012 Frederick Furness Publishing
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