1,721,045 research outputs found

    Role of Precursors and Doping Agents in Producing 3D-Printed PEGDA–PDANI Electroactive Composites by an In Situ Polymerization Approach

    Get PDF
    The methodologies for producing composite materials based on conducting polymers (CPs) and 3D-printed polymeric materials are promising to combine the complex geometries of 3D objects with the charge transport properties of CPs. Among the latter, polyaniline (PANI) has an edge because of its peculiar electrochemical behavior. Synthesis protocols starting from the aniline (ANI) monomer to produce the PANI phase are consolidated; however, a series of controversies are related to the use of this reactant, including a potential toxicity. To obtain safer synthetic procedures for fabricating electrical and electrochemically active 3D composite materials, this research exploits an alternative precursor, namely, the aniline dimer (DANI), for the in situ synthesis of polydianiline (PDANI) via oxidative polymerization within 3D-printed polyethylene glycol diacrylate (PEGDA) objects. Factors such as the molecular weight and swelling degree of PEGDA matrix, as well as the nature of PDANI's doping agents, are found to be crucial to modulate the type of redox mechanism, the charge transport properties, and the impedimetric response of 3D-printed PEGDA-PDANI composites. The possibility to produce PEGDA objects in complex 3D shapes (discs, dumbbell, and trabecular structures), coupled with the charge transport and electroactive performances of the PDANI filler, are promising for exploiting PEGDA-PDANI systems as active interfaces in a wide range of electronic applications

    Resonating Behaviour of Nanomachined Holed Microcantilevers

    Get PDF
    The nanofabrication of a nanomachined holed structure localized on the free end of a microcantilever is here presented, as a new tool to design micro-resonators with enhanced mass sensitivity. The proposed method allows both for the reduction of the sensor oscillating mass and the increment of the resonance frequency, without decreasing the active surface of the device. A theoretical analysis based on the Rayleigh method was developed to predict resonance frequency, effective mass, and effective stiffness of nanomachined holed microresonators. Analytical results were checked by Finite Element simulations, confirming an increase of the theoretical mass sensitivity up to 250%, without altering other figures of merit. The nanomachined holed resonators were vibrationally characterized, and their Q-factor resulted comparable with solid microcantilevers with same planar dimension

    A contamination-free electrolyte-gated organic transistors platform for high-accuracy tumor biomarker detection

    Get PDF
    A novel biosensor platform for high-accuracy tumor biomarker detection exploiting contamination free microfluidics for increasing the signal-to-noise ratio has been successfully developed and tested. Electrolyte-gated organic Transistors (EGOT) has been employed to detect an important tumor marker, Angiopoietin-2 (Ang2). Although organic semiconductors have become popular in the last years in biosensing applications due to their many advantages, there is still a main concern about stability and selectivity. This work presents major improvement in terms of the stability and selective detection of Ang2 in the range of interest for biomedical applications. The semiconducting polymer poly[3-(5-carboxypentyl)thiophene (P3CPT) is deposited by picoliter volume control and micrometer diameter of the droplet to allow for high uniformity and repeatability from sample to sample. The optimized gold electrodes improve the detection of the minimal concentration of the target and microfluidic interfacing by a specific pattern with the desired dimensions is obtained by UV-lithography and wet etching. A microfluidics with multiple flow control allows for maintain a constant fresh solution without analytes on reference gate electrode, while another inlet and functionalized gate is used for sensing, thus reaching high stability and reproducibility. All these (four) optimizations lead to new measuring protocol and new 3D printed top cover that ensure better stabilization and repeatability of the results. The device has successfully detected Ang2 concentrations as low as 10 pM in saline, therefore demonstrating the ability of the device to detect clinically relevant concentrations

    Going Beyond Counting First Authors in Author Co-citation Analysis

    Get PDF
    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
    corecore