40 research outputs found
variazione del contenuto di delta-9- tetraidrocannabinolo (THC) nella cannabis in Europa: revisione sistematica della letteratura
No full textla revisione sistematica presentata in questo lavoro ha come obiettivo quello di verificare la sussistenza di evidenze scientifiche circa l'andamento temporaledel potere stupefacente della herbal cannabis reperibile in Europa. Sono stati in particolare ricercati ed esaminati tutti gli studi scientifici condotti in Europa riguardanti il contenuto di THC, rinvenuto in materiale a scopo ricreazionale derivato da foglie e inflorescenze della specie cannabis sativa L
Wolves & the MHC: variability, hybridization and mate choice in the Italian wolf population
No full textIsolated small populations may experience low adaptability and increased extinction risks due to reduced genetic variability, especially if at important functional genes such as the Major Histocompatibility Complex (MHC). We investigated the variability of three class-II genes (DRB1, DQA1, DQB1) in the Italian wolf population, which was long isolated and is now expanding after a recent bottleneck. Compared to other populations, we still found a remarkable MHC variability, showing signatures of historical selection (high dN/dS ratio). The Italian wolves are known to hybridize with domestic dogs, and dog-derived MHC alleles were detected in some genetically-admixed individuals. Background microsatellite and MHC loci did not show reduced variability due to the recent bottleneck. Thus, the population recovery seems not to be threatened by reduced MHC variation nor by deep introgression of domestic dog alleles.
The observed variability could be also influenced by reproductive patterns, which can rely upon MHC similarity between mates. Based on pedigree data of wild-living packs, as reconstructed from extensive non-invasive genetic sampling, we tested the hypothesis of non-random mate choice in 26 breeding pairs. Results showed an unexpected prevalence of MHC-based assortative mating, with excess of peptide similarity between breeding pair members as compared to random expectations. Moreover, variation in both relatedness and heterozygosity showed significant positive correlations with fitness traits (total offspring, years as reproducers, mean offspring per year) deduced from pedigrees. These findings suggest possible advantages for breeders that are more related at the MHC, but not at the genetic background. This balance of general inbreeding avoidance, MHC-assortative mating and heterozygote advantage can reflect the social structure of the species, potentially maximizing the adaptation to the environmental pressures
Rainfall-induced slope instabilities in pyroclastic soils: The case study of Mount Albino (Campania region, southern Italy)
No full textThis paper shows the results of a research aimed at analyzing the susceptibility and hazard, at the source areas, of slope instabilities involving shallow deposits of pyroclastic soils and characterised by own triggering mechanisms. This goal is pursued – at large scale (1:5,000) – with reference to Mount Albino, a carbonatic relief prone to different types of rainfall-induced slope instabilities (i.e., hyperconcentrated flows, debris flows and debris avalanches) which threaten the municipality of Nocera Inferiore (Campania region,
southern Italy). In particular, susceptibility and hazard analyses specifically deal with the hyperconcentrated flows and are carried out via the use of heuristic and deterministic procedures thanks to the availability of geological and geomorphological information as well as data on both stratigraphic settings and geotechnical characteristics of potentially involved pyroclastic soils. The results highlight the role played by the above predisposing factors along with the conditions characterising the boundary-value problem at hand on the triggering mechanisms whose proper modelling is fundamental for a suitable assessment of the source volumes which can be mobilized during critical rainfalls
Phylogeny
No full textThis folder contains matrices used for the phylogenetic analyses and resulting trees
Correction to: Repeated amino acid PET imaging for longitudinal monitoring of brain tumors (Clinical and Translational Imaging, (2022), 10, 5, (457-465), 10.1007/s40336-022-00504-w)
No full textThe article “Repeated amino acid PET imaging for longitudinalmonitoring of brain tumors”, written by Francesco Cicone, et al., was originally published Online First without Open Access. After publication in volume 10, issue 5, page 457–465 the author decided to opt for Open Choice and to make the article an Open Access publication. Therefore, the copyright of the article has been changed to © Author(s) 2022 and the article is forthwith distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit. The original article has been corrected
Chern Numbers of Uniruled Threefolds
No full textIn this paper we show that the Chern numbers of a smooth Mori fibre space in dimension three are bounded in terms of the underlying topological manifold. We also generalise a theorem of Cascini and the second named author on the boundedness of Chern numbers of certain threefolds to the case of negative Kodaira dimension
Gli effetti indotti sul costruito da frane a cinematica lenta
No full text2008 - 2009Landslides - alone or in combination with other natural disasters such as earthquakes, volcanic
eruptions, floods etc. - Represent a major cause of casualties and property damage in terms of direct
and indirect costs.
For this reason, it’s interesting, either for the scientific community and for that technique, to
study aimed at the prediction of the effects associated with the action of landslides on the elements
at risk and, therefore, the estimation of their vulnerability.
As for this, the extreme complexity of the problem has, in fact, contributed to the practical
absence of standardized procedures.
The research carried out as part of this thesis aims to make a contribution in this direction with
specific reference to aspects concerning the estimation of physical vulnerability, or of the
consequences, in terms of expected damage, are predictable structures that interact with the bodies
of landslides kinematics active or slow, if quiescent, occasionally reactivated.
Additional reasons for the research are to be found in extreme dissemination of these
phenomena on the Italian territory, as it was recently revealed by the studies undertaken in the
context of the preparation of plans for the hydrogeological Excerpt (PSAI) and Landslide Project (
Inventory of Landslide in Italy), and the consequences that may result from the research in terms of
land management.
For the estimation of the vulnerability, it is necessary to study, analysis and interpretate the
interaction between the landslide and the vulnerable elements (in terms of single element exposed
or sets of elements) according to the following logic flow of operations (Varnes, 1984; Cruden and
Fell, 1997; Cascini 2005; Pisciotta, 2008): characterization of landslides or potential; estimate of its
intensity; identification of the exposed element or set of elements exposed; vulnerability
assessment.
As part of this methodological approach, the research activities were focused, at first on the
definition of the parameters useful to estimate the intensity of landslides and on the identification of
the most appropriate criteria for the identification of the elements at risk two different scales of
territorial representation (average and detail).
So, the real definition of physical vulnerability has been specializing in a different way
depending on the assumptions made at the two scales of work.
Having established the general criteria which determine the approach adopted, the activities
were aimed at the development of innovative procedures, based on the so-called "model of the
consequences", for the estimation of physical vulnerability... [edited by Author]VIII n.s
Perspectives on design creativity and innovation research: 10 years later
No full textGreen Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Methodologie en Organisatie van Desig
Identifying Complex DNA Contamination in Pig-Footed Bandicoots Helps to Clarify an Anomalous Ecological Transition
No full textOur understanding of the biology of the extinct pig-footed bandicoots (Chaeropus) has been substantially revised over the past two decades by both molecular and morphological research. Resolving the systematic and temporal contexts of Chaeropus evolution has relied heavily on sequencing DNA from century-old specimens. We have used sliding window BLASTs and phylogeny reconstruction, as well as cumulative likelihood and apomorphy distributions, to identify contamination in sequences from both species of pig-footed bandicoot. The sources of non-target DNA that were identified range from other bandicoot species to a bird—emphasizing the importance of sequence authentication for historical museum specimens, as has become standard for ancient DNA studies. Upon excluding the putatively contaminated fragments, Chaeropus was resolved as the sister to all other bandicoots (Peramelidae), to the exclusion of bilbies (Macrotis). The estimated divergence time between the two Chaeropus species also decreases in better agreement with the fossil record. This study provides evolutionary context for testing hypotheses on the ecological transition of pig-footed bandicoots from semi-fossorial omnivores towards cursorial grazers, which in turn may represent the only breach of deeply conserved ecospace partitioning between modern Australo-Papuan marsupial orders
Service level and Value to Customer as key business drivers: a case studying a leader truck industry
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