1,721,278 research outputs found
IX Ciclo de Debates sobre Bioética, Diplomacia e Saúde Pública: Manoel Barral Netto: biologia sintética em perspectiva dual: conquistas e ameaças à saúde global
No full textIX Ciclo de Debates sobre Bioética, Diplomacia e Saúde Pública. Palestrante: Manoel Barral Netto, Vice-presidente de Educação, Informação e Comunicação da Fundação Oswaldo Cruz (VPEIC/Fiocruz).
Data: 16/04/2018
Local: Salão Internacional da Escola Nacional de Saúde Pública Sérgio Arouca (ENSP), Fiocruz, campus de Manguinhos, Rio de Janeiro
A simple method for assessing the binding of concanavalin A to mononuclear cell surfaces: no interference of visceral leishmaniasis serum on this binding
No full textWe report a simple method for evaluating the binding of concanavalin A (ConA) to human peripheral blood mononuclear cells (PBMC). The binding is evidenced by an immunoenzymic assay using peroxidase-conjugated immunoglobulins of a rabbit anti-ConA serum. Using the method we show that sera from patients with American leishmaniasis do not interfere with binding of ConA to PBMC
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
In Vivo Lymphocyte Activation and Apoptosis by Lectins of the Diocleinae Subtribe
No full textMem Inst Oswaldo Cruz 2001, Volume 96, Number 5, pp. 673-678 In Vivo
Lymphocyte Activation and Apoptosis by Lectins of the Diocleinae
Subtribe Theolis Barbosa, Sérgio Arruda, Benildo Cavada, Thalles
Barbosa Grangeiro, Luiz Antônio Rodrigues de Freitas, Manoel
Barral-Netto Code Number: oc01105 ABSTRACT: This paper reports the
overall effects of three lectins, extracted from Canavalia
brasiliensis, Dioclea violacea, and D. grandiflora, on BALB/c mice
popliteal draining lymph nodes. These lectins have presented high
stimulatory capacity on lymph node T cells. Additionally, they were
able to induce apoptosis and inflammation (frequently associated with
high endothelial venule necrosis). The data presented here suggest that
the Diocleinae lectins studied can stimulate in vivo T cell activation
and apoptosis, as well as present important side effects. KEYWORDS:
adjuvants, apoptosis, Diocleinae, lectin Copyright 2001 Mem Inst
Oswaldo Cru
In Vivo Lymphocyte Activation and Apoptosis by Lectins of the Diocleinae Subtribe
No full textMem Inst Oswaldo Cruz 2001, Volume 96, Number 5, pp. 673-678 In Vivo
Lymphocyte Activation and Apoptosis by Lectins of the Diocleinae
Subtribe Theolis Barbosa, Sérgio Arruda, Benildo Cavada, Thalles
Barbosa Grangeiro, Luiz Antônio Rodrigues de Freitas, Manoel
Barral-Netto Code Number: oc01105 ABSTRACT: This paper reports the
overall effects of three lectins, extracted from Canavalia
brasiliensis, Dioclea violacea, and D. grandiflora, on BALB/c mice
popliteal draining lymph nodes. These lectins have presented high
stimulatory capacity on lymph node T cells. Additionally, they were
able to induce apoptosis and inflammation (frequently associated with
high endothelial venule necrosis). The data presented here suggest that
the Diocleinae lectins studied can stimulate in vivo T cell activation
and apoptosis, as well as present important side effects. KEYWORDS:
adjuvants, apoptosis, Diocleinae, lectin Copyright 2001 Mem Inst
Oswaldo Cru
Fibroblast stimulating activity of extracts of hepatic granulomata of Schistosoma mansoni-infected rodents with marked or slight hepatic fibrosis
No full textVariations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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