251,138 research outputs found
Does an equivalent of the "ventral node" exist in chick embryos? A scanning electron microscopic study
No full textThe internal organs of vertebrates show species-specific left-right (L-R) asymmetries. Questions on the embryonic origin of these asymmetries have been fascinating embryologists since the 19th century. During the past years, remarkable progress has been made in answering these questions. Evolutionary highly conserved molecular signaling cascades have been identified that start from Hensen's node and transfer side-specific identity to the embryonic left and right halves. However, the question of what initiates these signaling cascades has remained unanswered. Studies on mouse embryos have shown that: the ventral surface of Hensen's node consists of a ciliated epithelium called the ventral node. Recent findings suggest th;lt the monocilia of ventral nodel cells generate a leftward flow of extracellular fluid possibly leading to the accumulation of an unknown morphogen at the left of the node, which then might st-art the signaling cascades. This hypothesis might explain the fact that gene defects causing ciliary dyskinesia are frequently associated with situs anomalies. Studies on chick embryos led to the discovery of the L-R signaling cascades. However, whether an equivalent of the ventral node exists in avian embryos remained unknown. Therefore, I examined the endoderm and epiblast of early chick embryos for the presence of monociliated cells. In the endoderm, a population of monociliated cells indeed was present. These cells, however, were neither confined to the area of Hensen's node nor did they form the predominant cell population at this location. In the epiblast, monociliated cells formed the predominant cell population at the periphery of the blastodisc but, only a relatively small subpopulation of epiblast cells at Hensen's node. These findings suggest that, in the early chick embryo, an equivalent of the ventral node of mouse embryos neither exists on the ventral nor the dorsal surface of Hensen's node. It is unlikely that nodal cilia are required for initiating the L-R patterning in chick embryos
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
"Closing the R&D Gap, Evaluating the Sources of R&D Spending"
No full textBoth spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
On Deverbal -(I)r-, -(U)r- and Changes in Aktionsart and Manner of Actions of Verbs
No full textFiiller kılmış hususiyetleri bakımından vurgulu bir dönüşüm anına sahip olup olmadıklarına göre dönüşümlü ve dönüşümsüz olarak tasnif edilir. Ancak fiillerin bu hususiyetleri söz dizimine katılan tarz, miktar, yer ve yön, zaman zarfları, kip, zaman ekleri ve tasvir fiili yapıları vb. vasıtasıyla değişiklik gösterebilmektedir. Bunun yanında fiilden fiil yapan ekler de çatı ilişkileri yanında eklendikleri fiillerde farklı kılmış ve tarz değişiklikleri de meydana getirebilmektedir. Çalışmada -(l)r-, -(U)r- ekleri vasıtasıyla günümüz Türkiye Türkçesi ve Tarihi Türkçedeki bir kısım örnekler çerçevesinde zikredilen kılmış ve tarz değişiklikleri üzerinde durulmuştur.
Categories of manner of action (aktionsart) of verb lexemes are classified as tranformational and non-transformational according to whether they have a crucial transformatian limit and intermediate cursus. A verb lexeme may change its basic phase structure in sentax through recategorization shifters like manner, directional, temporal adverbs, grammatkal aspect makers and post-verb constructions ete. In addition, the basic phase structure of a verb lexeme may be changed by deverbal suffixes. In this article was examined recategorization of a basic phase structure of a verb lexeme through deverbal -(l)r-, -(U)r- in some instances in Turkey Turkish as well as Old and Medieval Turkic
Letter from R. R. Zellick, Assistant Trust Officer, Anglo California National Bank of San Francisco, to Joseph R. Goodman, October 2, 1942
No full textLetter from R. R. Zellick, Assistant Trust Officer at The Anglo California National Bank of San Francisco, to Joseph R. Goodman, regarding property owned by Dave Tatsuno. Zellick mentions a dispute between current tenants and Tatsuno, and that Tatsuno has asked Goodman to help locate trustworthy tenants.Personal correspondence, organizational records, government documents, publications, and other papers created or collected by Joseph R. Goodman documenting the forced removal and incarceration of Japanese Americans during World War II, as well as organized resistance to incarceration. Included in the collection are records of the Japanese Young Men's Christian Association and the Japanese American Citizens' League in San Francisco, including papers of the Japanese YMCA's executive secretary Lincoln Kanai; Sakai family papers; Goodman's correspondence to and from Japanese American incarcerees, organizations opposing forced removal and incarceration of Japanese Americans, the War Relocation Authority, and others; publications, photographs, and ephemera from the Topaz Relocation Center, where Goodman taught high school; War Relocation Authority records and publications; and newspaper clippings, pamphlets, and reports about forced removal and incarceration created by various government, religious, and civic organizations, in California and nationwide
Request for production of documents – UCPR r 222 – manner of compliance
No full textIn John Kallinicos Accountants Pty Ltd v Dundrenan Pty Ltd [2009] QDC 141 Irwin DCJ considered the nature of a party’s obligation under r 222 of the Uniform Civil Procedure Rules 1999 (Qld) (UCPR) to produce documents referred to in the parties’ pleadings, particulars or affidavits. The decision examined whether the approach in Belela Pty Ltd v Menzies Excavation Pty Ltd [2005] 2 QdR 230 in relation to disclosure of documents under UCPR r 214 also applied to production of documents under r 222
The NoiseFiltersR Package: Label Noise Preprocessing in R
No full textIn Data Mining, the value of extracted knowledge is directly related to the quality of the used data. This makes data preprocessing one of the most important steps in the knowledge discovery process. A common problem affecting data quality is the presence of noise. A training set with label noise can reduce the predictive performance of classification learning techniques and increase the overfitting of classification models. In this work we present the NoiseFiltersR package. It contains the first extensive R implementation of classical and state-of-the-art label noise filters, which are the most common techniques for preprocessing label noise. The algorithms used for the implementation of the label noise filters are appropriately documented and referenced. They can be called in a R-user-friendly manner, and their results are unified by means of the "filter" class, which also benefits from adapted print and summary methods.Univ Granada, Dept Comp Sci & Artificial Intelligence, E-18071 Granada, SpainUniv Sao Paulo, Inst Ciencias Matemat & Comp, Trabalhador Sao Carlense Av 400, BR-13560970 Sao Carlos, SP, BrazilUniv Fed Sao Paulo, Inst Ciencia & Tecnol, Talim St 330, BR-12231280 Sao Jose Dos Campos, SP, BrazilUniv Fed Sao Paulo, Inst Ciencia & Tecnol, Talim St 330, BR-12231280 Sao Jose Dos Campos, SP, BrazilWeb of ScienceSpanish Research ProjectAndalusian Research PlanBrazilian grant-CeMEAI-FAPESPFAPESPSpanish Research Project: TIN2014-57251-PAndalusian Research Plan: P11-TIC-7765CeMEAI-FAPESP: 2013/07375-0FAPESP: 2012/22608-8FAPESP: 2011/14602-
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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