3,912 research outputs found

    A 5-Approximation for Universal Facility Location

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    In this paper, we propose and analyze a local search algorithm for the Universal facility location problem. Our algorithm improves the approximation ratio of this problem from 5.83, given by Angel et al., to 5. A second major contribution of the paper is that it gets rid of the expensive multi operation that was a mainstay of all previous local search algorithms for capacitated facility location and universal facility location problem. The only operations that we require to prove the 5-approximation are add, open, and close. A multi operation is basically a combination of the open and close operations. The 5-approximation algorithm for the capacitated facility location problem, given by Bansal et al., also uses the multi operation. However, on careful observation, it turned out that add, open, and close operations are sufficient to prove a 5-factor for the problem. This resulted into an improved algorithm for the universal facility location problem, with an improved factor

    Data for Gupta et al., "Estimating the Meridional Extent of Adiabatic Mixing in the Stratosphere using Age-of-Air", JGR:Atmospheres,

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    Model data and post-processed data supporting the creation of the manuscript "Estimating the Meridional Extent of Adiabatic Mixing in the Stratosphere using Age-of-Air" submitted to JGR:Atmospheres in August 2022. 1) The netCDF files created through post-processing of full model data in FORTRAN are shared in the /data/ directory. These file contains the zonal mean circulation statistics based on Gupta et al. (2020), age-of-air transport diagnostics based on Linz et al. (2021), and the novel \Gamma-\Theta circulation streamfunction introduced in this study. The /data/ directory also contains MATLAB .mat data files for the transport diagnostics obtained from WACCM. 150 days of actual GFDL-FV3 model data in the northern hemisphere, between 0.1 hPa-500 hPa pressure levels is also provided to support external computations and validation. 2) The Jupyter notebook used for final computation and figures production is provided in .ipynb, .html and .pdf formats in /code/. All the files referred to in the notebook are stored in the /data/ directory. Corresponding author : Aman Gupta, [email protected], [email protected], [email protected]

    Corrigendum: Capital Inflows and House Prices: Aggregate and Regional Evidence from China

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    In the paper ‘Capital Inflows and House Prices: Aggregate and Regional Evidence from China’ by H. An, et al., printed in the December 2016 issue, there was a missing acknowledgement section for funding resources. On page 451, the acknowledgement section should appear after the corresponding information as: “Correspondence: Rakesh Gupta, Department of Accounting, Finance and Economics, Griffith Business School, Griffith University, Nathan Campus QLD 4111. [email protected] *This work was financially supported by the Humanities and Social Science Foundation of Ministry of Education of China (16YJA790001).” The author apologises for this error and any confusion it may have caused.No Full Tex

    Development of Novel Biosensing Platforms using Metal, Metal-Insulator-Metal (MIM) and Quantum Materials

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    Rapid and accurate testing of easily transmissible diseases is essential to prevent extensive breakouts, identify infected individuals for timely treatment, and curb transmission by taking suitable measures. With the advancement of nanotechnology, biosensors are becoming an indispensable tool in drug development, biomedicine, disease monitoring, and food safety. Nanophotonic biosensors rely on the interaction of the evanescent field with target bioanalytes to produce a measurable optical signal output. This thesis is a groundbreaking achievement in the field of nanoresonator-based biosensor platforms. Through the use of finite-difference timedomain (FDTD) simulations, we have developed three distinct designs that incorporate metal-insulator-metal (MIM), gold (Au), and 2D material nanoresonators. These designs have the potential to revolutionize the biosensor industry and pave the way for new and innovative applications. The design of two different MIM nanoresonator configurations, (i) metal-insulatormetal nanopillar array and (ii) metal nanoresonator array on insulator-metal thin film stack, were nurtured. The influence of the geometric parameters such as diameter, pitch, insulator layer’s materials and thickness, the shape of individual nanoresonators, and the array arrangements were cultivated efficiently to balance the leakiness of MIM nanoresonators for achieving high surface sensitivity. With the best design parameters, MIM nanoresonators were fabricated and experimentally validated with varying concentrations of polystyrene beads. The MIM nanopillar array device demonstrated the best experimental detection sensitivity of 6.54 ± 0.7 nm/decade for polystyrene beads of 100 nm diameter. Polystyrene beads were used to test the device’s performance as their optical properties, such as refractive index and extinction coefficient, match well with most bioanalytes. Despite the high degree of tunability of localized surface plasmon resonance field, the fabrication complexity associated with different MIM nanoresonators imposes limitations for mass production and cost-effectiveness. In this context, plasmonic Au nanoresonators were proposed, and the best design was established using FDTD simulation to enhance the localized surface plasmon resonance (LSPR) field. The devices were fabricated with the best design parameters and were biofunctionalized, demonstrating SARS-CoV-2 detection with one of the lowest limits of detection 1 virus-like particle (VLP) µL−1 and detection sensitivity of 1.32 ± 0.08 nm/decade. We also proposed a design of a portable point-of-care biosensing platform using our Au nanoresonators. Furthermore, we delved into different metasurface designs of MoS2 nanoresonators to mitigate the field dissipation issues that plague the plasmonic metal nanostructures. We introduced three groundbreaking MoS2 nanoresonator designs for biosensor platforms, established novel fabrication methods and experimentally evaluated their performances. MoS2 was selected as the material for the nanoresonator due to its high refractive index and low absorption coefficient in the visible wavelength range. Moreover, MoS2 has minimal cytotoxicity and biocompatibility, making it suitable for various biosensing applications. The best design obtained from FDTD simulations were utilized to fabricate nanoresonators with the large area (1 inch × 1 inch) MoS2 thin film grown by pulsed laser deposition system. The experimental measurements provided a detection sensitivity of 13.71 ± 1.7 nm/decade and a limit of detection (LOD) of 4 polystyrene beads. By innovating three distinct nanophotonic platforms, we have showcased the adept detection of 100 nm-sized polystyrene beads and SARS-CoV-2 virus-like particles. This thesis research not only underscores the accomplishment of nanophotonics but also symbolizes its profound capacity to make a monumental impact in biosensing. Our ingenious approach has demonstrated capability and illuminated a path where nanophotonics emerges as a transformative force, fundamentally reshaping the biosensing landscape with unparalleled precision and efficacy

    EP-MPCHS: Edge Server-Based Cloudlet Offloading Using Multi-Core and Parallel Heap Structures

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    The increasing computational demands of mobile applications, like image caption generators and Google Lens, result in higher memory and Random Access Memory (RAM) usage. Thus, to offboard the computational workload of these applications, cloud-based edge server frameworks have been in demand lately. In the age of cloud-based computing, the study aims to create a hybridized cloudlet placement algorithm that caters to reducing latency, increasing bandwidth, reducing network flow pressure, and optimizing the edge server resources. The primary condition of the utilized placement algorithm is to prioritize the cloudlets enabling the reduction of latency, increase of bandwidth, and CPU utilization. This study proposes Edge Priority Placement using Multi-Core and Parallel Heap Structures (EP-MCPHS) utilizing the min heap prioritization technique to deduce the placement of each cloudlet. This incorporates the priority queue-based resource allocation system which ensures that the optimal process is selected to the minimum available edge server allowing the reduction of resource utilization, increased latency, decreased network flow, and enhanced bandwidth. The algorithm also reinforces the technique with a multi-latent parallel head provisioning or Ph.C. with parallel processing, allowing reduced process starvation for the non-processing cloudlets. EP-MCPHS reduces the end time for cloudlet processing by 27.36%, increases bandwidth by 71.27%, and data flow by 24.81%. This study incorporates the SimPy framework for simulation testing using the EdgeSimPy framework for edge server simulation. The study compares the results achieved by the architecture with the Min-Max fairness algorithm. It provides statistical testing across time intervals to showcase the ability of the placement algorithm even with increasing workload

    First person – Akash Gupta

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    First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. Akash Gupta is first author on ‘A novel and cost-effective ex vivo orthotopic model for the study of human breast cancer in mouse mammary gland organ culture’, published in BiO. Akash conducted the research described in this article while a PhD Scholar in Rajendra Mehta's lab at IIT Research Institute, Chicago, USA. He is now an assistant research scientist in the lab of Syreeta L. Tilghman at the University of Arizona, Department of Medicine, Tucson, USA, investigating drug efficacy modeling using human organoids culture for the treatment of cancers

    Environmental Management: A study of Manufacturing Units working in the Gujarat State

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    People of India are lucky in the richness of natural resources and diversity of living resources. Uniqueness of our planet earth is the most exiting fact. Earth is the only planet that can support life. The earth is gifted with thousands of rivers that supplies sweet water to quench out thirst, an atmosphere that supplies oxygen for our survival, a natural ozone umbrella that protects us from dangerous ultra violet rays, a green carpet of vegetation that recycles the waste gases like carbon dioxide to oxygen, a large number of attractions like rainbows, lightening and thunders. There are three types of environments including, atmosphere, hydrosphere and biosphere. The nature itself keeps balance among these three layers. Biological wealth on the land includes vegetation, animals, birds, and insects, which are interdependent. The environment in all its facets of biological diversity, the air, soil water, and the forests constitute the essential life support system on which we depend. The main and foremost aims of environment are to study of nature ‘Environment is the sum of all social, economical, biological factors which constitutes the surroundings of man, who is both creator and moulder’. In India, industrial sector plays major role in creation environmental imbalance. Researcher selects this area particularly to study environmental problems in Gujarat State. Samples are selected from five main area of cement, pharmaceutical, textile, chemical VI and fertilizer. Rational of this sample is that Gujarat Industrial Economy majority dependent on these industries. This study has significant utility for decision making authority, industry, academician and researcher

    Pulsed Laser Deposition of 2D materials and Complex Perovskites

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    Pulsed laser deposition is a physical vapor deposition technique used for the growthof single crystal epitaxial thin films on a variety of substrates. Due to the high en-ergy of the ablated particles from the target, the plasma plume consists of atoms,molecules, ions and electrons, PLD allows for high efficiency in the deposition ofmaterials with complex stoichiometry.Two very different materials are grown using PLD in this study, namely, a 2D ma-terial called Molybdenum sulphide (MoS2) for electronic device applications and anovel perovskite material called for La0.3M0.7Fe0.7Cr0.3O3-δ(M = Ca, Sr) (LCFCrand LSFCr) for solid oxide fuel cell applications. This thesis consists of a studyof the effect of the variation of PLD parameters on the film quality, and thus, anoptimization of these parameters to obtain thin films with desirable properties.The thin films of MoS2grown in different conditions have been analyzed usingmaterial and electronic characterization techniques to study the film properties.Single crystal epitaxial growth was obtained with a crystal phase correspondingto (002) orientation of MoS2. A high uniformity with a film RMS roughness ofaround 0.17 nm was obtained for 5 monolayers of MoS2. XPS analysis was usedto observe a presence of small amounts of MoO3and semimetallic 1T-MoS2in thesemiconducting 2H-MoS2thin films. Transmission and absorption studies over dif-ferent thicknesses of the deposited films showed the presence of B and C excitonictransitions in the film. Hall measurement has also been performed for the thin films over different thick-nesses to study electrical properties. With Van der Pauw measurements over anarea of around 25 mm2, an increasing trend was observed from 5 to 13 monolay-ers of MoS2and a decreasing trend from 13 to 56 monolayers of MoS2, with thehighest electron mobility of 76.92 cm2/Vs observed in our studies for 13 mono-layers of MoS2. This trend matched the studies of FET mobility measured overdevices with different thicknesses observed in literature. These promising studiessuggest potentially higher mobilities on PLD grown MoS2thin film based FETdevices. These studies serve as a starting point for several future applications ofPLD deposited MoS2thin films in scaled electronic devices and sensors and flexibleelectronic devices and sensors.Thin films of LMFCr (LCFCr and LSFCr) were deposited under different condi-tions and analyzed using using material characterization techniques to study thefilm properties. Under optimized growth conditions, epitaxial single crystal thinfilms of LCFCr with a (002) crystal phase was observed. A high film uniformity with the lowest RMS roughness of 0.15 nm obtained for LCFCr. XPS analysis helped study and confirm the elemental states present in the thin films. These optimized thin films can be used for solid oxide fuel cell applications in the futur
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