75 research outputs found

    Generalized Abstracted Mean Values

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    In this article, the author introduces the generalized abstracted mean values which extend the concepts of most means with two variables, and researches their basic properties and monotonicities

    Trachischium sushantai Raha & Das & Bag & Debnath & Pramanick 2018, sp. nov.

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    Trachischium sushantai sp. nov. (Figures 1, 2) Holotype. ZSI25651 A, National Zoological Collection, ZSI, Kolkata; adult female; from ‘ Jammu’ (Jammu & Kashmir state, India); collected on 4th August, 1993, during Jammu survey; name of collector is given in register as ‘ Rajtilok’. Diagnosis. Trachischium sushantai sp. nov. can be diagnosed by a combination of the following characters: a single nasal and PF, SL (R/L) 6/6, post-ocular 1, DSCH:M: V 13:13:13; VEN 152; SC 23 pairs of which those on anterior half of tail are as long as wide and regular hexagon/ rhomboid shaped, TAL/TL ratio of 0.11, head and dorsum uniform dark brown, venter brown with cream or yellow border on the trailing edges of VEN and SC. Etymology. The new species is named after Sushanta Kumar Das, father of the second author of present paper. He is an enthusiastic nature observer who have spent a significant amount of time of his life in forested areas of West Bengal (India) and nurtured the same interest in the second author. The specific epithet, a patronym, is a noun in genitive case. Description of holotype. Adult female; incised on underside; SVL and TAL of 276 mm and 35 mm respectively; tail small, TAL /TL ratio being only 0.11; head small (HL 7.8 mm, 2.8 % of SVL); head width (HW 4.7 mm) greater than head height (HH 4.2 mm); head indistinct from neck; eye small (ED 1 mm, 12.8 % of HL); ESN 2.9 mm; rostral slightly wider than high (1.1 mm and 0.8 mm, respectively); internasals paired, much shorter than the single PF; frontal pentagonal, 2.8 mm long, longer than its distance from the posterior edge of rostral (1.9 mm), around two and half times wider than supraocular; parietals, being 4.4 mm long, are longer than frontal; 1 pre- and 1 post-ocular; loreal nearly twice wider than high and is in contact with nasal, internasal, frontal, preocular and 1 st and 2nd SL; very small nostril in single forward directed nasal; SL (R/L) 6/6, 1 st smallest and 6th largest, 3rd and 4th touching eye; IL (R/L) 6/6, 1st, 2nd and 3rd IL touch the anterior genial while the 4th one contacts both the anterior and posterior genials; anterior genials longer than posterior genials; TEMP (R/L) 1+2/1+2; maxillary teeth in life were probably around 16 or 17 (counting for missing teeth which were evident by longer than usual gaps between extant teeth at some places), subequal; dorsal scales smooth, including those around the region of the tail base, DSCH:M: V 13:13:13; VEN 152; anal divided; SC 23 pairs, anterior subcaudals (those on anterior half of tail) are as wide as long (4SCW/L 1.05 and 5SCW/L 1.01), regular hexagonal or rhomboid shaped, SC become slightly wider than long on posterior part of tail; tail tip in a spike like scale. Coloration in preservative: head and dorsum uniform dark brown; edges of scales on lower jaw lighter colored; venter brown with outeredges of VEN cream or dirty yellow; underside of tail light brown with the posterior edges of SC bordered with lighter yellowish cream. Comparisons. T. sushantai sp. nov. differs from T. monticola in possessing 13 rows of dorsal scales (vs. 15 rows in the latter), undivided PF (vs. divided PF in T. monticola), 1 post-ocular (vs. usually 2 in the latter) and 152 VEN (vs. less than 125 VEN in T. monticola [Smith 1943])(Table 2). T. sushantai sp. nov. differs from T. leave in having 6 SL, 1 PF, 23 SC and a brown venter (vs. 5 SL, 2 PF, 29– 39 SC and a yellow venter in T. leave). T. sushantai sp. nov. can be diagnosed from T. tenuiceps by having a shorter tail (TAL /TL 0.11), 1 PF, 1 postocular, 23 SC of which the anterior ones are regular hexagonal or rhomboid and a brown venter (vs. TAL /TL 0.15– 0.18, 2 PF and 2 post-oculars, 28–42 SC of which anterior ones are transversely elongated and yellowish or orange ventral coloration in T. tenuiceps). T. sushantai sp. nov. differs from T. guentheri by having a brown venter and 23 pairs of SC (vs. a coral red venter in T. guentheri and SC more than 30 in T. guentheri [Smith 1943]). The new species most closely resembles T. fuscum from which it can be distinguished by its shorter tail (TAL / TL 0.11) compared to T. fuscum (vs. TAL /TL 0.13–0.18 [± 0.14 in 27 specimens] in T. fuscum), 23 pairs of SC of which anterior ones are regular hexagonal/rhomboid with 4SCW/L 1.05 and 5SCW/L 1.01 (vs. 30–44 SC in T. fuscum [31–41 in females examined by us], SC wider than long and are not regular hexagonal/rhomboid with 4SCW/L 1.33–3 [± 1.6 in 22 specimens] and 5SCW/L 1.27–2.7 [± 1.6 in 21 specimens] in physically examined specimens [specimens of T. fuscum examined from photographs too had SC number within the range given here and were distinctly wider than long]). Distribution. Trachischium sushantai sp. nov. is currently known only from its type locality in Jammu (Jammu & Kahmir, India) (Figure 3). Natural history. Unknown.Published as part of Raha, Sujoy, Das, Sunandan, Bag, Probhat, Debnath, Sudipta & Pramanick, Kousik, 2018, Description of a new species of genus Trachischium with a redescription of Trachischium fuscum (Serpentes: Colubridae: Natricinae), pp. 549-561 in Zootaxa 4370 (5) on pages 550-553, DOI: 10.11646/zootaxa.4370.5.6, http://zenodo.org/record/114735

    New Extensions of Kannan's and Reich's Fixed Point Theorems for Multivalued Maps Using Wardowski's Technique with Application to Integral Equations

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    The metric function generalizes the concept of distance between two points and hence includes the symmetric property. The aim of this article is to introduce a new and proper extension of Kannan’s fixed point theorem to the case of multivalued maps usingWardowski’s F-contraction. We show that our result is applicable to a class of mappings where neither the multivalued version of Kannan’s theorem nor that of Wardowski’s can be applied to determine the existence of fixed points. Application of our result to the solution of integral equations has been provided. A multivalued Reich type generalized version of the result is also established.The authors are thankful to the learned referees for careful reading and valuable comments towards improvement of the manuscript. Research of the first author (P. Debnath) is supported by UGC (Ministry of HRD, Govt. of India) through UGC-BSR Start-Up Grant vide letter No. F.30-452/2018(BSR) dated 12 Feb 2019.FacultyReviewe

    Study On Modification Of Edible Oil For Improving Physico-Chemical And Thermal Properties.

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    This Dissertation / Report is the outcome of investigation carried out by the creator(s) / author(s) at the department/division of Central Food Technological Research Institute (CFTRI), Mysore mentioned below in this page

    Studies on Physico-Chemical Properties of Fried Oils

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    This Dissertation / Report is the outcome of investigation carried out by the creator(s) / author(s) at the department/division of Central Food Technological Research Institute (CFTRI), Mysore mentioned below in this page

    Study of Mass Transfer Phenomena During Frying of Potato Slice

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    This Dissertation / Report is the outcome of investigation carried out by the creator(s) / author(s) at the department/division of Central Food Technological Research Institute (CFTRI), Mysore mentioned below in this page

    Frying Studies of Potato Strips using Dry Coating Materials

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    This Dissertation / Report is the outcome of investigation carried out by the creator(s) / author(s) at the department/division of Central Food Technological Research Institute (CFTRI), Mysore mentioned below in this page

    Rotatory vibration of sphere of higher order viscoelastic solid

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    An attempt is made to investigate the rotatory vibration of a sphere of higher order viscoelastic solid considering higher order strain rate and stress rate. The general frequency equation is obtained for this type of vibration of a sphere. As a special case of this analysis, the frequency equations for the first order and the second order viscoelastic solids are derived. It is shown that the classical frequency equation for an isotropic elastic solid follows from this analysis

    Simultaneous Estimation of Amlodipine Besylate and Nebivolol Hydrochloride in Pharmaceutical Tablets Formulation by RP-HPLC Using PDA Detector: Simultaneous estimation of amlodipine besylate and nebivolol hydrochloride

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    The present work was undertaken with the aim to develop and validate a rapid and consistent RP-HPLC method in which the peaks will be appear with short period of time as per ICH Guidelines.The separation was achieved on a stainless steel analytical column, Eclipse XDB plus C18 column (4.6 X 150 mm; 5 μm) in an isocratic mode. The mobile phase was composed acetonitrile and 0.01 M ammonium acetate (pH adjusted to 4.5 using glacial acetic acid), which were mixed in the ratio of 50: 50. The flow rate was monitored at 1.0 mL/min. The wavelength selected for detection was 265 nm. The retention time found for amlodipine besylate and nebivolol hydrochloride was 2.967 and 3.510 min, respectively. The % recovery was 100.20- 100.86 for amlodipine and 100.20 - 100.78 for nebivolol. The linearity was established in the range of 5-25 μg/mL for amlodipine and 10-50 μg/mL for nebivolol. The slope, intercept, and correlation coefficient were found to be 314.2x, +162.4, and 0.999 for amlodipine besylate and 248x, -305.7, and 0.9998 for nebivolol hydrochloride, respectively. The limits of detection for amlodipine besylate and nebivolol hydrochloride obtained by the proposed method was 0.07 and 0.20 μg/ml and the limits of quantification for amlodipine besylate and nebivolol hydrochloride obtained by the proposed method was 0.23 and 0.61 μg/mL, respectively. The method was found to be suitable for the quality control test of amlodipine besylate and nebivolol hydrochloride simultaneously in a bulk drugs as well as in a formulations

    STABILITY INDICATING RP-HPLC METHOD FOR THE ESTIMATION OF QUETIAPINE FUMARATE IN BULK AS WELL AS IN PHARMACEUTICAL DOSAGE FORM

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    This study was designed to develop and validate a simple, sensitive, precise, and specific stability indicating reverse phase high-performance liquid chromatographic (HPLC) method for estimation of Quetiapine Fumarate in bulk and its tablet dosage form. The HPLC separation was carried out by reverse phase chromatography on Thermo column Symmetry C18 (4.6 x 150mm, 5 mm) with a mobile phase composed Sodium dihydrogen phosphate and the pH was adjusted to 4.0 by Orthophosporic Acid & Methanol in the ratio of 35:65 v/v in isocratic mode at a flow rate of 1.0 ml/min. The run time was maintained for 6mins. The detection was monitored at 290 nm. The calibration curve for Quetiapine Fumarate was linear from 20 to60 µg/ml. The inter-day and intra-day precision was found to be within the limits. The proposed method was adequate sensitivity, reproducibility, and specificity for the determination of Quetiapine Fumarate in bulk and its tablet dosage forms. The limit of detection [LOD] and limit of quantification [LOQ] for Quetiapine Fumarate were found to be 0.01 µg/ml and 0.03 µg /ml respectively. The Accuracy recoveries were 100.0-100.4% and reproducibility was found to be satisfactory. The bulk active pharmaceutical ingredient was subjected to  thermal,  photolytic,  hydrolytic  (acidic  and  basic)  and  oxidative  stress  conditions  and  stressed  samples  were analyzed by the proposed method. The method was validated in terms of linearity, precision, accuracy, specificity and robustness. All the validation was done as per ICH guidelines. The proposed method was simple, fast, accurate, and precise for the quantification of Quetiapine Fumarate in the dosage form, bulk drugs as well as for routine analysis in quality control. Key-Words: Quetiapine Fumarate, RP-HPLC, ICH, Stability Indicating Studies, LOD, LOQ
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