1,721,074 research outputs found

    Mosquito surveillance and disease outbreak risk models to inform mosquito-control operations in Europe

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    Surveillance programs are needed to guide mosquito-control operations to reduce both nuisance and the spread of mosquito-borne diseases. Understanding the thresholds for action to reduce both nuisance and the risk of arbovirus transmission is becoming critical. To date, mosquito surveillance is mainly implemented to inform about pathogen transmission risks rather than to reduce mosquito nuisance even though lots of control efforts are aimed at the latter. Passive surveillance, such as digital monitoring (validated by entomological trapping), is a powerful tool to record biting rates in real time. High-quality data are essential to model the risk of arbovirus diseases. For invasive pathogens, efforts are needed to predict the arrival of infected hosts linked to the small-scale vector to host contact ratio, while for endemic pathogens efforts are needed to set up region-wide highly structured surveillance measures to understand seasonal re-activation and pathogen transmission in order to carry out effective control operations

    Assistive products and childhood neurodisability: a retrospective study on factors associated with aids/orthoses prescription

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    BACKGROUND: Children affected by pathologies causing neurodisability go through motor, cognitive, sensory and other limitations. The selection of assistive products can influence their level of independence and quality of life. AIM: The present study investigated the possibility to assess the equipment needs of children with neurodisabilities, based on their clinical characteristics. DESIGN: A retrospective observational study. SETTING: Outpatients. POPULATION: Inclusion criteria: diagnosis of cerebral palsy or genetic/chromosomal/syndromic disorders, age range 0-18 years, intelligence quotient evaluation, medical history of positive or negative presence of epilepsy and of communication disorders, admission at our neurorehabilitation service between 2007 and 2017, and registration of all equipment prescribed to each child. METHODS: In 192 children (111 males, 57.81%) we evaluated the relationship between several independent variables (diagnosis, sex, Gross Motor Function Classification System level, intelligence quotient, history of epilepsy and communication disorders) and equipment prescription by means of logistic regression models. RESULTS: Our data showed significant correlation between the Gross Motor Function Classification System level and the equipment prescribed. A history of seizures was negatively correlated with walker prescriptions (the log odds of prescription decreases by -2.156; CI: -4.16 to -0.65) and positively with those of stroller (the log odds increases by 1.427; CI: 0.22 to 2.69). Stroller and knee-ankle-foot orthoses and hip-knee-ankle-foot orthoses prescriptions were negatively correlated with the cerebral palsy diagnosis. The prescription of foot orthoses was positively correlated with mental retardation (the log odds increases by 0.358; CI: 0.12 to 0.61). A negative correlation between communication disorders and the prescription of ankle-foot orthoses and communication/learning devices was also found (the log odds decreases by -0.833; CI -1.66 to -0.01). CONCLUSIONS: Several clinical characteristics correlate with specific equipment needs. CLINICAL REHABILITATION IMPACT: The definition of the clinical characteristics with a potential predicting value, may facilitate the task of physician on choosing what is more appropriate to prescribe, as well as the authorizing office responsible for evaluating the appropriateness of prescriptions. Furthermore, it could be possible to foresee the care needs in terms of type and number of aids/orthoses and to guarantee every disabled child the possibility to take advantage of the same opportunities. (Cite this article as: Assenza C, Cacciatore D, Manica M, Iosa M, Foti C, Gobbetti T, et al. Assistive products and childhood neurodisability: a retrospective study on factors associated with aids/orthoses prescription

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Modelling the impact of multi-­host helminth parasites on hosts’ population dynamics

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    This work is inspired by multi-annual observations of helminth infection levels and population densities of rock partridge (Alectoris graeca saxatilis) that is an endangered species in the Dolomitic Alps (northern Italy). Field data show that the nematode parasite Ascaridia compar infect both rock partridge and black grouse (Tetrao tetrix), and also suggest a competitive interaction between the two galliform species that share a common spatial domain in the Alps. We hypothesized two possible interaction mechanisms: direct competition and parasite-mediated competition, also called apparent competition, and we used mathematical models as a proof-­-of-­-principle verification of these hypotheses. Outputs from the direct competition model are in contrast with field observations, outputs of the parasite-­mediated competition model qualitatively fit the observed pattern suggesting that the sharing of parasite free-living stages between the two species can trigger the competition playing an important role in the decline of rock partridge in Trentino region. The model has been extended to a spatial model that allows for a partial habitat overlap, showing the role of diffusion in shaping either exclusion or spatial segregation of the competitor less tolerant of infestatio

    Spatio-temporal distribution of aedes albopictus and culex pipiens along an urban-natural gradient in the Ventotene Island, Italy

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    The distribution of mosquitos and their corresponding hosts is critical in public health to determine the risk of transmission for vector-borne diseases. In this pilot study conducted in the small Mediterranean island of Ventotene, a known stopover site for migratory birds, the spatio-temporal distribution of two major mosquito vectors is analyzed from the natural to urban environment. The results show that Aedes albopictus aggregates mostly near areas with a human presence and the urban landscape, while Culex pipiens is more spatio-temporally spread, as it can also be found in wilder and less anthropized areas where the availability of human hosts is limited. Culex pipiens is also active earlier in the year. From a microgeographical perspective, our results confirm the anthropophilic spatial distribution of Ae. Albopictus, while suggesting that the circulation of bird zoonosis, such as West Nile, could be favored by the Cx. pipiens distribution. The results highlight the different ecology of the vectors and the interplay with their hosts, even at a small scale. The current evidence may help in forecasting the risk of pathogen transmission and surveillance planning

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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