1,721,185 research outputs found
Analytical prediction of composite beams response in fire situations
No full textIn this paper an extension of the method of the Fourier series expansion to the fire analysis of composite beams is presented. In particular the extension concerns the introduction of the temperature dependent interaction of all the components: steel beams, concrete slab and steel connectors. These last are considered of finite stiffness, and a proper account is given to the combined effect of thermal degradation of the properties, and stress amplification caused by the differential thermal expansion across the interface.
The proposed method compares very well with some experimental fire tests of simply supported and framed composite beams. Due to its relative simplicity and speed, it can be used for design purposes in evaluating the critical temperature in terms of critical deflection. Finally we recall that the method is capable of dealing with every type of fastening distribution, such as discontinuous or variable length
Cefiderocol for resistant Gram negatives: linking in vitro activity with clinical effectiveness
No full textDamage Assessment in Actual Fire Situations by Means of Non Destructive Techniques and Concrete Tests
No full textIn the paper the problem of the damage assessment in post real fire situations is discussed once more at the light of some integrated non destructive testing procedures. The illustration of the method is developed with reference to a real fire accident where extensive laboratory and site analyses were worked out. The analysis of the compartment and the concrete investigation results allow to define the damage field in the structural elements and to design a sensible strengthening intervention leading finally to a safety margin not less than the original one
Combination therapy in severe Acinetobacter baumannii infections: an update on the evidence to date.
No full textAcinetobacter baumannii is a drug-resistant Gram-negative pathogen increasingly causing hospital-acquired infections in critically ill patients. In this review, we summarize the current mechanisms of antimicrobial resistance in A. baumannii and describe in detail recent in vitro and in vivo experimental data on the activity of antimicrobial
combinations against this microorganism. We then introduce the rationale for the use of combination antibiotic therapy in resistant A. baumannii infections. Finally, we present and critically discuss both uncontrolled clinical studies and the few randomized clinical trials
of combination antimicrobial therapy for these infections, with a special focus on ongoing multinational trials and optimal approach to future research in this field
Oropouche virus infection: What internal medicine physicians should know
No full textNot required for Clinical Insigh
Design and Execution of Aluminium Space Frame Advertising Panels and Towers
No full textSpace frame modular construction systems are widely employed as a support for advertising panels, mainly for their strength, modularity, and lightness. In recent times, solutions based on aluminium extruded profiles have demonstrated their capability to solve successfully the problem with high corrosion resistance, and
low maintenance costs.
The space frame systems made with aluminium components allow for a very large set of possible solutions, while unifying the possibility to fix neon filled boxed letters, fabric or solid panels, flags or other advertising devices. Moreover, the system is very light and can be lifted to the building roof and composed without
the help of huge cranes and machinery.
Very often, the solution of the advertising system atop a commercial centre is defined only few days before the opening of the centre; without designing the centre roof with support points able to resist the very large wind forces that act on the provided panels.
In these situations, the capability of the modular systems to adapt their shape and support concept in order to connect the available roof strong points with the panel supporting frame is extremely useful. Therefore, the aluminium modular frame solutions are superior to every other possibility.
In this paper, the design of an aluminium space frame is summarized, with reference to a large set of constructed advertising towers and panels. The problem of the evaluation of the wind forces is outlined and useful remarks about the fatigue
resistance of aluminium components are drawn.
Careful presentation of the design criteria of some outstanding installations gives information about the wide set of problems that these adaptive structures can easily solve
Unraveling the Puzzle: Health Benefits of Probiotics—A Comprehensive Review
No full textA growing number of probiotic-containing products are on the market, and their use is increasing. Probiotics are thought to support the health of the gut microbiota, which in turn might prevent or delay the onset of gastrointestinal tract disorders. Obesity, type 2 diabetes, autism, osteoporosis, and some immunological illnesses are among the conditions that have been shown to possibly benefit from probiotics. In addition to their ability to favorably affect diseases, probiotics represent a defense system enhancing intestinal, nutritional, and oral health. Depending on the type of microbial strain utilized, probiotics can have variable beneficial properties. Although many microbial species are available, the most widely employed ones are lactic acid bacteria and bifidobacteria. The usefulness of these bacteria is dependent on both their origin and their capacity to promote health. Probiotics represent a valuable clinical tool supporting gastrointestinal health, immune system function, and metabolic balance. When used appropriately, probiotics may provide benefits such as a reduced risk of gastrointestinal disorders, enhanced immunity, and improved metabolic health. Most popular probiotics, their health advantages, and their mode of action are the topic of this narrative review article, aimed to provide the reader with a comprehensive reappraisal of this topic matter
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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