1,721,222 research outputs found

    A New Efficient Route to Imidazo[4,5-c]pyrazol-5-ones

    No full text
    The synthesis of imidazo[4,5-c]pyrazol-5-ones (6) is reported. 5-Amino-4-ethoxycarbonylaminopyrazoles 3a-g when heated at 200°for 2 hours afford 6a-g. In a similar manner imidazo[4,5-c]pyrazol-5-one (6a) is readily obtained from 4-amino-5-ethoxycarbonylaminopyrazole (5a)

    "Il Lembo di Gastrocnemio nella Chirurgia dei Sarcomi del Ginocchio"

    No full text
    Il Lembo di Gastrocnemio nella Chirurgia dei Sarcomi del Ginocchi

    Unicameral and aneurysmal bone cysts

    No full text
    Unicameral and aneurysmal bone cysts are considered tumorlike conditions of unclear origin. The diagnosis of unicameral bone cysts is almost always based on the radiographic appearance, whereas aneurysmal bone cyst imaging may sometimes mimic a sarcomatous lesion. Several pathogenetic hypotheses [correction of hypothesis] reported in literature have been described. Classifications have been proposed to detect the activity of the cysts and to predict the prognostic behavior. The results observed with different options of treatment have been discussed

    Surgical treatment for spinal metastases.

    No full text
    The treatment of spinal metastases aims to improve or maintain neurological status, achieve local control of the disease and maintain or restore spinal stability. Three types of surgery are possible: ▪ Palliative (the most frequent): consists of laminectomy and posterior stabilization. It is performed to treat complications from the metastases (pathological fractures and spinal cord compression), but it does not directly treat the bone lesion, leaving its treatment to other therapies (radio–chemo–hormone–immunotherapy). It is indicated in patients with a severe prognosis or with a good predictive response to radiotherapy (Figure 7.1) [1–4];▪ Adjuvant (frequent): consists of total or partial piecemeal removal of the lesion combined with other local therapies, such as radiation, embolization and thermal ablation. It is indicated in all patients who have a fair prognosis (Figure 7.2);▪ Radical (rare): consists of complete en bloc removal of the metastasis with a layer of healthy surrounding soft tissue to free patients from the disease, at least in that site. It is indicated in patients with good prognosis (Figure 7.3) [1–4]

    Going Beyond Counting First Authors in Author Co-citation Analysis

    Full text link
    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
    corecore