86,584 research outputs found

    Preliminary investigation on antioxidant, antibacterial and antiproliferative activities on Pleurotus eryngii var. thapsiae, as potencial source of bioactive compounds

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    Since ancient times mushrooms have been appreciated as food, and in more recent years their medicinal properties have been increasingly exploited. Apart from their use as simple foods, mushrooms are being explored as functional ingredients in the development of novel foods, mushroom-based products, and food supplements. Several studies on medicinal mushrooms have highlighted their wide pharmacological activities, including antioxidant, antimicrobial, anti-inflammatory, and antitumor properties. These pharmacological effects can be attributed to the rich bioactive metabolites composition found in fungi, primarily in the mycelium and sporophores. The most studied molecules are phenolic compounds, proteins, fatty acids, terpenes, terpenoids, steroids, and vitamins. Several reports have also been conducted on polysaccharides, which are the structural components of the mushroom cell wall and exhibited a strong biological activity. Heteroglycans, peptidoglycans, and polysaccharide-protein complexes are polysaccharides that contribute to functional properties that mushroom are known to have, but the most abundant and well-known compounds are alfa- and beta-glucans. Pleurotus (Fr.) P. Kumm. is one of the most widely taxonomic group and include different cultivated and economically important mushrooms. These mushrooms are widely used in human nutrition all over the world and are also recognized as medicinal mushrooms. The genus includes facultative saprotrophs or biotrophs which grow in association with plants of the Apiaceae family, the P. eryngii species complex is undoubtedly noteworthy. In this study, we focused on the use of P. eryngii var. thapsiae Venturella, Zervakis & Saitta, whose basidiomes grow in association with Thapsia garganica L. and have been currently reported so far only in Sicily (Italy). The basidiomes growing on two different substrates were used, the first based on wheat straw and the second based on a mixture of wheat straw and Aegilops spp., a common wheat weed. Aqueous crude extracts produced by two different techniques, conventional low-temperature, and ultrasound-assisted extraction, were used. These extracts were tested by radical scavenging activity (DPPH), thiobarbituric acid reactive substances (TBARS) formation inhibition, oxidative haemolysis inhibition assay (OxHLIA), antimicrobial (food and clinical bacteria and fungi) and antiproliferative assays on different human tumor cell lines. Preliminary results showed interesting antimicrobial activities against several Gram-positive and Gram-negative bacteria, including multi-resistant strains, as well as antifungal activities against Aspergillus brasiliensis. Regarding antiproliferative potential, very interesting results were observed against gastric (AGS), colorectal (CaCo-2), breast (MCF7), and liver (NCI-H460) cancer cell lines. Further evaluation of the biological activities and chemical characterization of polysaccharides within the extracts is in progress

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    [Newspaper Clipping: Author Claims Evidence of Second JFK Assassin #1]

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    Newspaper article titled "Author Claims Evidence of Second JFK Assassin." The article states that author Richard J. Whalen concluded "that there is circumstantial evidence to support the theory of a second assassin in the shooting of President John F. Kennedy.

    Also By The Same Author: AKTiveAuthor, a Citation Graph Approach to Name Disambiguation

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    The desire for definitive data and the semantic web drive for inference over heterogeneous data sources requires co-reference resolution to be performed on those data. In particular, name disambiguation is required to allow accurate publication lists, citation counts and impact measures to be determined. This paper describes a graph-based approach to author disambiguation on large-scale citation networks. Using self-citation, co-authorship and document source analyses, AKTiveAuthor clusters papers, achieving precision of 0.997 and recall of 0.818 over a test group of eight surname clusters

    John F. Kennedy telegram to Roosevelt

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    Jersey Homesteads (later the Borough of Roosevelt) was established in the 1930s as an agro-industrial cooperative community. It was established specifically for urban Jewish garment workers, many of whom had emigrated from Europe. President John F. Kennedy sent a telegram to the citizens of Roosevelt, New Jersey, apologizing for not being able to attend the memorial dedication in honor of former President Franklin Delano Roosevelt. (Jersey Homesteads became Roosevelt in 1945 in honor of the president.) President Kennedy expressed his gratitude to the people of Roosevelt for constructing the memorial, and commented that it will serve as a constant reminder of Roosevelt's good works

    Avaliação do potencial das folhas da Cynara carcunculus L. como ingrediente funcional

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    Cynara cardunculus L., usualmente denominada por cardo, é uma espécie herbácea nativa dos países da bacia do Mediterrâneo. Esta espécie exibe um diversificado número de aplicações industriais1. É utilizada na medicina tradicional devido às suas propriedades benéficas para a saúde. O cardo é também considerado um alimento funcional devido à sua rica composição em compostos com propriedades funcionais (como por exemplo, ácidos fenólicos, flavonoides, fibra, inulina)2,3. No presente estudo, a influencia do estado de maturação nas propriedades bioativas das folhas de cardo foi analisada.Os autores agradecem à Fundação para a Ciência e Tecnologia (FCT, Portugal) pelo apoio financeiro ao CIMO (UIDB/00690/2020 e UIDP/00690/2020) e SusTEC (LA/P/0007/2020); pela bolsa de doutoramento de F. Mandim (SFRH/146614/2019), aos contrato-programa de emprego cientifico institucional de M.I. Dias e L. Barros (contrato-programa de emprego cientifico institucional) e J. Pinela (CEECIND/01011/2018).info:eu-repo/semantics/publishedVersio

    Logarithmic variance profiles and the corresponding f-1 spectra of temperature fluctuations in turbulent Rayleigh-Bénard convection

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    We report experimental results for the temperature variance 2(z) and the corresponding frequency spectra P(f) in turbulent Rayleigh-Bénard convection (RBC) in a cylindrical sample of aspect ratioT= D/L = 1:00 (D = 1:12 m is the diameter and L = 1:12 m the height). The measurements were conducted in the Rayleigh-number range 1011 < Ra < 1:35 1014 and Pr ' 0:8. For Ra = 1:35x1014, 2(z) could be described well by a logarithmic dependence on the vertical position z in a range of z 1 < z < z 2 with z 1 ' 70 and z 2 = 0:1L. Here L=(2Nu) is the thickness of a thin thermal sublayer adjacent to the horizontal plate where the heat flux (denoted by the Nusselt number Nu) is carried mostly by thermal diffusion. In the log layer, we found that the temperature spectra had a significant frequency range over which P(f) f with close to 1. As Ra decreased, increased so that the log layer became thinner. At Ra = 2:05 1011, z 2 < z 1 and therefore there was no range for a log layer. Correspondingly, the temperature spectrum near the horizontal plate did not have the f1 scaling form either

    Maine author Franklin F. Gould recalls his first glimpse of the outside world

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    Maine author Franklin F. Gould recalls his first glimpse of the outside world as he relates how, as a young farm boy in the late 1800\u27s, he drove his father\u27s horses on an errand to an icebound river

    Mapping the Discipline of the Olympic Games An Author-Cocitation Analysis

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    The authors conducted an author cocitation analysis on prominent authors writing about the Olympics during the 1990s. Author cocitation is an established bibliometric technique that can be used to measure the relative similarities of topics written about by the cited authors. This enables a visual representation of the “intellectual space” of the discipline, in this case the Olympics, to be created for the period under review. So core and peripheral research areas are identified, along with their major contributors. The representation appears as a two-dimensional cluster-enhanced map. Subject expertise was then applied to the results to place labels on the generated clusters of authors and their topics

    Avaliação do potencial das folhas da Cynara carcunculus L. como ingrediente funcional

    No full text
    Cynara cardunculus L., usualmente denominada por cardo, é uma espécie herbácea nativa dos países da bacia do Mediterrâneo. Esta espécie exibe um diversificado número de aplicações industriais1. É utilizada na medicina tradicional devido às suas propriedades benéficas para a saúde. O cardo é também considerado um alimento funcional devido à sua rica composição em compostos com propriedades funcionais (como por exemplo, ácidos fenólicos, flavonoides, fibra, inulina)2,3. No presente estudo, a influencia do estado de maturação nas propriedades bioativas das folhas de cardo foi analisada.Os autores agradecem à Fundação para a Ciência e Tecnologia (FCT, Portugal) pelo apoio financeiro ao CIMO (UIDB/00690/2020 e UIDP/00690/2020) e SusTEC (LA/P/0007/2020); pela bolsa de doutoramento de F. Mandim (SFRH/146614/2019), aos contrato-programa de emprego cientifico institucional de M.I. Dias e L. Barros (contrato-programa de emprego cientifico institucional) e J. Pinela (CEECIND/01011/2018).info:eu-repo/semantics/publishedVersio
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