1,354,322 research outputs found
Medieval body embalming in the Blessed Ranieri da Borgo (†1304)
No full textRanieri da Borgo was a lay brother of the Conventual Franciscans, dead on November 1st, 1304. The local Municipality played a significant role in obtaining the balm for body preservation, in recording miracles since the very day of his death, and allowing the construction of the main altar above the crypt hosting his body. In order to plan a new recognition, we performed a preliminary survey. Probably in his original clothes, the mummified body was lying inside a wooden casket dating to XVI Century. The right arm was lacking, due to past burglary, whereas the left hand and feet were in excellent state of preservation. The face was covered with homogeneous brownish matter, suggesting embalming. Intentionally preserved bodies of charismatic religious people are considered the most ancient examples of body embalming in Europe. A review of the literature allowed us to find only ten artificially embalmed Holy Bodies from 1297 to 1482. In this context, Ranieri could represent the eleventh and oldest male example. Further analyses are needed to confirm this historical assumption
Aberrant Pattern of Cytokeratin Expression in Olfactory Neuroblastoma: A Potential Diagnostic Pitfall.
No full text6q27 subtelomeric deletions: Is there a specific phenotype?
No full textWe read with great interest the report of Mosca et al. [2010] in theMay issue of the Journal, describing a patient with a 5.65Mb
deletion on chromosome 6q27 (ranging from 165.24Mb to the
6q telomere at 170.89 Mb)associated with intellectual disability and a Ehlers–Danlos (EDS) like phenotype. We would like to further delineate the phenotypic spectrum of these rearrangements by reporting two additional patients with this chromosomal abnormality.
Patient 1 is a 17-year-old girl, with a history of moderate
psychomotor retardation, hypotonia and a sacral lipoma, that was surgically removed at age 5. She had mild dysmorphic features (downslanting, narrow palpebral fissures, a broad nasal root, malar hypoplasia, prominent ears, and thin vermillion of the upper lip). Brain MRI performed at age 16 as part of the investigations for the intellectual disability, showed an atypical cerebellar cyst, and evidence of periventricular nodular heterotopia. She has never had seizures
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
John Mandarano, oral history audio, 10/12/2017
No full textInterviewee: John Mandarano
Interviewer: Zack Modine, Matt Morgante, Tommy Murphy
Date: October 12, 2017
Location: SUNY Cortland Memorial Library, Cortland, New York
Length: 50:02
John Mandarano was born on February 26, 1954 and has lived in the city of Cortland his entire life. The eldest of five children he has had a good positive relationship with both of his parents and all of his siblings. He was especially close with his father who owned and operated a machine and tool shop in town until 1976. John is a Machinist by trade, a Career he was inspired to do because of his father. His Father’s shop got most of its business from the Brockway Motor Company and when Brockway shutdown in 1977 most of the necessity for a Machine shop in Cortland went away as well. His father’s shop, Cortland Machine and Tool is also how he became close with his younger brother, Patrick, because of his father having both of them around his machine shop when they were young. As a result of their experience in their father’s Machine shop, John and Patrick have their own business venture together where they manufacture custom pieces that people order from them. They both enjoy this because they are able to pick and choose which projects they work on giving them freedom in their work. John worked all over Cortland County throughout his 40+ year career as a Machinist working for his father’s shop as well as Haskell Machine and Tool in Homer, New York. Then when Haskell Machine and Tool burned down in 1978 he moved to Coller Machine in Ithaca, New York. After working at Coller for a period of time he then went back to Cortland to work for Wilson Sporting Goods, making tools and jigs and machinery for their racquetball line of products. John began working for Pall Trinity in Cortland, New York and has been working there for the past 36 years. John is also very involved in the History of Cortland He is a member of the Cortland County Historical Society as well as a board member of the CNY..
Mandarano, John, 2017
No full textJohn Mandarano was born on February 26, 1954 and has lived in the city of Cortland his entire life. The eldest of five children he has had a good positive relationship with both of his parents and all of his siblings. He was especially close with his father who owned and operated a machine and tool shop in town until 1976. John is a Machinist by trade, a Career he was inspired to do because of his father. His Father’s shop got most of its business from the Brockway Motor Company and when Brockway shutdown in 1977 most of the necessity for a Machine shop in Cortland went away as well. His father’s shop, Cortland Machine and Tool is also how he became close with his younger brother, Patrick, because of his father having both of them around his machine shop when they were young. As a result of their experience in their father’s Machine shop, John and Patrick have their own business venture together where they manufacture custom pieces that people order from them. They both enjoy this because they are able to pick and choose which projects they work on giving them freedom in their work. John worked all over Cortland County throughout his 40+ year career as a Machinist working for his father’s shop as well as Haskell Machine and Tool in Homer, New York. Then when Haskell Machine and Tool burned down in 1978 he moved to Coller Machine in Ithaca, New York. After working at Coller for a period of time he then went back to Cortland to work for Wilson Sporting Goods, making tools and jigs and machinery for their racquetball line of products. John began working for Pall Trinity in Cortland, New York and has been working there for the past 36 years. John is also very involved in the History of Cortland He is a member of the Cortland County Historical Society as well as a board member of the CNY Living History Center. He helps plan a Brockway truck show that goes down Cortland’s Main Street every August. He is also a part of planning the exhibits in the CNY Living History Center helping design the layout of what should be shown and the rotation that they should display all of the pieces of history that they have there. His passion for the history and preservation of Cortland is inspiring.https://digitalcommons.cortland.edu/cortlandoralhistory/1008/thumbnail.jp
The implementation of a commercially available multi-gene profile test for breast cancer characterization in a department of pathology: what have we learned from the first 100 cases?
No full textAnalysis of breast cancer prognostic and predictive factors is still nowadays poorly accurate and standardized. The advent of multi-gene expression profiles (MGEPs) has improved the prediction of breast cancer outcome, particularly regarding early luminal breast cancers (LBCs). The availability in our Institute of EndoPredict® (EP), a last-generation prognostic gene signature assay, has prompted us to study a series of LBCs, firstly verifying its reproducibility on six routine representative cases, either presenting non-optimal preanalytical conditions or different tumor samples from the same patient; secondly, correlating EP results on 8 retrospectively recruited samples with patients’ follow-up; thirdly, applying prospectively EP on 100 routinely diagnosed cases, assessing the oncologists’ and pathologists’ attitude toward it. The complete reproducibility of EP on all the samples investigated in the first phase allowed to state that EP overcomes the detrimental effects of an inaccurate pre-analytic phase, determining the most appropriate prognostic and predictive parameters of breast cancer. The second phase confirmed EP as a fundamental tool in guiding therapeutic decision, improving the classical bio-pathological characterization and recovering 38% patients’ inadequately managed. Finally, the study disclosed how oncologists sometimes inadequately requested EP, but also how it allows a better stratification of breast cancer otherwise considered poorly aggressive and not requiring an EP test, such as G1 neoplasms or tubular histotype. In conclusion, the introduction of EP test in an Anatomic Pathology Department emerges as a useful tool in routine breast cancer diagnosis, both for the characterization of individual cases and, as a result, for more appropriate therapeutic choices
Variations on the Author
No full text“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
John Mandarano, oral history transcript, 10/12/2017
No full textInterviewee: John Mandarano
Interviewer: Zack Modine, Matt Morgante, Tommy Murphy
Date: October 12, 2017
Location: SUNY Cortland Memorial Library, Cortland, New York
Length: 50:02
John Mandarano was born on February 26, 1954 and has lived in the city of Cortland his entire life. The eldest of five children he has had a good positive relationship with both of his parents and all of his siblings. He was especially close with his father who owned and operated a machine and tool shop in town until 1976. John is a Machinist by trade, a Career he was inspired to do because of his father. His Father’s shop got most of its business from the Brockway Motor Company and when Brockway shutdown in 1977 most of the necessity for a Machine shop in Cortland went away as well. His father’s shop, Cortland Machine and Tool is also how he became close with his younger brother, Patrick, because of his father having both of them around his machine shop when they were young. As a result of their experience in their father’s Machine shop, John and Patrick have their own business venture together where they manufacture custom pieces that people order from them. They both enjoy this because they are able to pick and choose which projects they work on giving them freedom in their work. John worked all over Cortland County throughout his 40+ year career as a Machinist working for his father’s shop as well as Haskell Machine and Tool in Homer, New York. Then when Haskell Machine and Tool burned down in 1978 he moved to Coller Machine in Ithaca, New York. After working at Coller for a period of time he then went back to Cortland to work for Wilson Sporting Goods, making tools and jigs and machinery for their racquetball line of products. John began working for Pall Trinity in Cortland, New York and has been working there for the past 36 years. John is also very involved in the History of Cortland He is a member of the Cortland County Historical Society as well as a board member of the CNY...
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