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    Choroid plexus cyst, corticocerebral necrosis and hydrosyringomyelia in a dog

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    A twenty-month-old Springer Spaniel presented with a history of episodic left head tilt appeared after physical effort six months before. The dog received oral prednisolone 0.8 mg/kg SID with slight improvement. After the neurological examination a cervical spinal cord/posterior fossa localization was suspected. When the prednisolone treatment was tapered off the neurological status deteriorated and was consistent with a diffuse cerebral localization. The magnetic resonance imaging of the brain revealed a well-defined mass (cm 1,7x1,2x2,3) within the fourth ventricle, hyperintense on T2-weighted images (T2WI) and hypointense on pre and post contrast T1-weighted images (T1WI); in T2WI a severe, diffuse, poor defined cortical hyperintensity in both cerebral hemispheres and in the dorsocaudal part of the cerebellar vermis. These areas were mildly hypointense in T1WI and enhanced diffusely on post-contrast T1WI. T2WI of the cervical spine showed a severe hydrosyringomyelia and a diffuse hyperintensity of the spinal cord. Histophatological investigation confirmed a widespread bilateral and symmetrical necrosis of cortical grey matter, a focal cystic lesion in the fourth ventricle consistent with a choroid plexus cyst (CPC), and a marked dilation of the central canal of the cervical spinal cord with two adjacent syrinx (hydrosyringomyelia). To our knowledge this is the first case reporting in the same patient two rare conditions as diffuse cerebrocortical necrosis and CPC. We suspected a peracute worsening of a chronic impairment in cerebrospinal fluid flow at the foramen magnum, due to the CPC, and a sudden increase of the intracranial pressure causing a diffuse ischaemic lesion of the cerebral cortex

    INFEZIONE SPERIMENTALE DELLA MAMMELLA CON S.AUREUS IN PECORE: MODIFICAZIONI DI ALCUNE ATTIVITÀ ENZIMATICHE NEL SIERO DI SANGUE, NEL SECRETO E TESSUTO MAMMARIO NELLE PRIME 48 ORE.

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    In pecore infettate sperimentalmente per via diatelica con un ceppo di S.aureus ed in animali controllo sono state valutate le attività enzimatiche di GGT, GOT, LDH, ICDH, CK e AlP nel siero di sangue e nel secreto mammario ad 8, 24, 32 e 48 ore dall'infezione, nonchè nel tessuto mammario a 48 ore. Le modificazioni dei valori delle attività esaminate sono state raffrontate con i rilievi dell'esame di ispezione e palpazione della mammella, con quelli dell'esame fisico-chimico e citobatteriologico del secreto, nonchè con i reperti anatomo-istopatologici ed ultrastrutturali della ghiandola mammaria. L'analisi dei risultati ottenuti ha permesso di evidenziare correlazioni significative tra l'andamento delle attività enzimatiche valutate ed i reperti anatomo-istopatologici. GOT, GOT, LDH, ICDH, CK and AlP activities have been evaluated in experimentally infected sheeps for the teat canal in blood serum and udder secretum after 8, 24, 32, and 48 hours and in udder tissue after 48 hours from infection. The same activities were also evaluated with the same protocol' in a control group. Changes in the above mentioned activities were compared with clinical findings, somatic cells count, bacteria investigations and anatomic-pathological and ultrastructural reports of mammary gland. The analysis of results showed correlations between alterations of enzymatic activities and anatomic-pathological specimens

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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