196,042 research outputs found
Outcome of 50 consecutive sinus lift operations.
No full textOutcome of 50 consecutive sinus lift operations.
Papa F, Cortese A, Maltarello MC, Sagliocco R, Felice P, Claudio PP.
Source
Department of Odontostomatologic and Maxillo Facial Sciences, University of Naples "Federico II", Italy.
Abstract
We report 50 patients who had sinus lift operations between 1995 and 1999 using different grafting materials [autologous bone, heterologous bone, and hydroxyapatite]. The casenote were analysed clinically (intraoperative and postoperative results and complications), radiographically (amount of augmented bone 6 months postoperatively), and histologically (quality of the new bone 12 months postoperatively). Our aim was to find out if the various bone grafting materials used resulted in different outcomes after adjustment for significant predictors. We found that hydroxyapatite was associated with the lowest rate of loss of grafted material (median, 2.4 mm) followed by the autologous bone from iliac crest (2.8 mm). Bovine bone shown the highest loss (3.3 mm).
PMID: 15993284 [PubMed - indexed for MEDLIN
Outcome of 47 consecutive sinus lift operations using aragonitic calcium carbonate associated with autologous platelet-rich plasma: clinical, histologic, and histomorphometrical evaluations.
No full textOutcome of 47 consecutive sinus lift operations using aragonitic calcium carbonate associated with autologous platelet-rich plasma: clinical, histologic, and histomorphometrical evaluations.
Papa F, Cortese A, Sagliocco R, Farella M, Banzi C, Maltarello MC, Pellegrini C, D'Agostino E, Aimola P, Claudio PP.
Source
Department of Odontostomatologic and Maxillo-Facial Sciences, University Federico II, Naples, Italy.
Abstract
BACKGROUND:
The reconstruction of the maxillary bone frequently represents a real challenge for maxillofacial surgeons especially regarding the best choice of a suitable material to produce the required bone augmentation.
AIM:
In this study, we summarize our clinical experience on 47 sinus lifts with lateral approach using a mixture of aragonitic calcium carbonate and autologous platelet-rich plasma compared with that of a previous published study in which bovine bone (LADDEC) and autologous bone were used in 50 sinus lift operations (Br J Oral Maxillofac Surg 2005;43:309-313).
MATERIALS AND METHODS:
We subjected 34 patients to sinus lift operation, for a total of 47 sinus lifts, using natural coral as osteoconductive material. This material, combined with autologous platelet-rich plasma, was placed onto the maxillary sinus floor, after carefully lifting the endosteum. Cases were clinically, radiographically, and histologically analyzed. Histomorphometrical analysis, tests of microhardness, and x-ray microanalysis were conducted comparing the various sample to controls obtained from the same patients.
RESULTS AND CONCLUSIONS:
Histomorphometrical analysis, microhardness test, and x-ray microanalysis demonstrated that the newly formed bone showed morphologic and structural characteristics that were similar for all the grafting materials compared (bovine bone, autologous bone, and coral). Although all the grafting materials did yield good results of maturation of the newly formed bone, best results were achieved using autologous bone.
PMID: 19881366 [PubMed - indexed for MEDLIN
Ultrastructural Investigation Demonstrating Reduced Cell Adhesion on Heparin-Surface-Modified Intraocular Lenses
No full textA major attention is focused at present to the surface characteristics of intraocular lenses (IOLs), which determine the biological response to the prostheses. There is now an overwhelming information on the fact that some cell types adhere to a lesser extent onto heparin-surface-modified (HSM) polymethylmethacrylate (PMMA) IOLs, either in vitro and in vivo. The present work aimed at sheding new insights by applying ultrastructural techniques of analysis. Our results basically confirm that human fibroblasts, platelets and monocytes are less in number when cultured onto HSM PMMA IOLs as compared to untreated PMMA IOLs. In addition: (1) the submicroscopic morphology of the cells cultured onto HSM PMMA IOLs appears to be normal, thus confirming the noncytotoxicity of the material; (2) fibroblasts grown onto PMMA IOLs are confluent and multilayered; they appear to be in a state of intense activity; the cytoskeletal elements are regularly arranged, and several points of contact at the interface are found; the rare cells present on HSM IOLs do not show at all any of these features; (3) the basic forms of resting and activated platelets are seen onto PMMA IOLs while no sign of activation is observed onto HSM IOLs, and (4) the ultrastructural morphology of monocytes does not differ significantly between the different IOLs. However, other studies are still in progress in order to localize and quantitate the specific receptors responsible for the eventual activation of these cells
Nostra esperienza sull’impiego di materiale osteoconduttore a base di corallo naturale nella metodica del sinus lift. Congresso Naz. Dei Docenti di Discipline Odontostomatologiche e Chirurgia Maxillo-Facciale. Roma 22-24 Aprile 2009
No full textHistological and clinical survey of polylactic-polyglycolic acid and dextrane copolymer in maxillary sinus lift: a pilot in vivo study
No full textAbstarct
Of various proposed alternatives to autogenous bone, a synthetic, degradable copolymer of PLA-GLA and dextrane seems to be a promising biomaterial for maxillary sinus lift. Consecutive partially edentulous patients showing severe monolateral posterior maxillary atrophy were treated via sinus lift using PLA-GLA-dextrane copolymer as the sole filler. Delayed implant positioning was performed and cores of regenerated tissues and native bone controls were retrieved and evaluated by light and electron microscopy, histomorphometry, microhardness and qualitative X-ray analysis. Seven sinuses in 7 patients were augmented with PLA-GLA-dextrane copolymer. Six to nine months after the copolymer ‘graft’, 17 bone cores were retrieved: all histological sections contained newly synthesized, mineralized material and new bone in various stages of development. Histomorphometry revealed average Trabecular Bone Volume (TBV) values ranging from 51% (6 months) to 77% (9 months). Backscattered scanning electron microscopy (BSE) in experimental and control samples confirmed histology findings. Microhardness values suggested newly formed bone at nine months was not as hard as native bone. Ca and P content was similar in 9-month regenerated and native bone. Seventeen implants were inserted in the second stage of surgery: resulting Implant Success (SR) and Cumulative Success (CSR) up to 3 years were 100% following Albrektsson’s criteria. Sinus lift augmentation using PLA-GLA-dextrane copolymer as the sole filler resulted in uneventful surgeries. New bone formation was evident histologically and its maturation was still in progress after 9 months. Successful, staged implant positioning was achieved in regenerated tissue.
Key words: sinus lift, PLA-GLA-dextrane copolymer, histomorphometric analysis, microhardness, X-ray microanalysi
Ceramic Films on the Plastic Component for Low Wear Joint Prostheses: A Pilot Study of a Challenging Approach
No full textMultifunctional ceramic thin films for high-performance orthopaedic implants
No full textProtective hard films on soft inorganic/organic substrates are appealing for several technological applications like solar cells, organic electronics, fuel cells, etc. The main concern is still related to the bad quality of the interface and to the weak mechanical properties of the film as a consequence of the low working temperatures mandatory to prevent substrate softening/melting. Our research activity at Rizzoli Orthopaedic Institute is mainly directed toward the deposition of functional ceramic thin films to improve the mechanical properties (and thus the clinical performances) of the load-bearing plastic component of the prosthetic implant. To this aim, we use a novel sputter-based electron deposition technique named Pulsed Plasma Deposition (PPD) able to provide nanostructured ceramic thin films highly adhered to the plastic substrate and with optimum mechanical performances even if working at room temperature and using very-soft substrates
Prevention of ischemia-reperfusion damage with polymerized superoxide dismutase.
No full textThe efficacy of preventing ischemia-reperfusion damage by employing native or modified (mPEG-SOD) superoxide dismutase in an experimental model of acute ischemia was tested in the left hind limb of 43 Wistar rats. A significative difference (p=0.004) of the survival leg rate was found in the group treated with mPEG-SOD (86.6%) compared with the control group (30%). This difference was confirmed both clinically and by TEM analysis of muscular specimens
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