175 research outputs found
Maktabat Al Muthanna Baghdad Feb-May 1962
No full textOn the same date, Ali Al-Mansouri issued an official financial statement confirming that the Al-Khanji Foundation owed a total of 11.375.أصدر علي المنصوري بيانًا ماليًا رسميًا بتاريخ 25 نيسان 1962 يُفيد بأن مؤسسة الخانجي مدينة بمبلغ إجمالي قدره 11,375
Physiological control of an implantable rotary blood pump / Mahdi Mansouri
No full textLeft ventricular assist devices (LVADs) are mechanical pumps that their usage expanded from bridging to recovery to bridging to decision, and destination therapy. A physiologically responsive pump control strategy, which automatically adjusts variations in the metabolic demands, is tremendously needed to maximize the quality of the implant recipients’ life. The aim of this dissertation is providing a robust physiological based controller, which could resist against all possible distortion during its working life.
At the first step, the performance of a number of previously proposed physiologically responsive controllers were comparably evaluated. The study proved applying a constant (static) controlling method could not provide the pump best controlling performance level, and indicates the demand of an adaptive (dynamic) controller, which will satisfy all physiological requisites. The results also suggested putting the focus on preload sensitivity of the ventricular myocardium. Such issue is an essential requirement for the Frank-Starling mechanism by which the left ventricular end-diastolic pressure (PLVED) controls the force of contraction of the left ventricle (LV) in proportion to the blood flow received from the right heart and pulmonary circulation.
At the next step a preload-based Starling-like controller for Implantable rotary blood pumps (IRBPs) using PLVED as the feedback variable was evaluated in a validated numerical model. The controller emulated the response of the natural LV to changes in PLVED. It was reported the performance of the preload-based Starling-like controller in comparison with recently designed pulsatility controller and constant speed operation. In handling the transition from a baseline state to test states, which included vigorous exercise, blood loss and a major reduction in the LV contractility (LVC), the preload controller outperformed pulsatility control and constant speed operation in all three test scenarios.
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The study third objection was realizing preload-based using a controlling technique that reinforced the system to rapidly reach the target pump flow within eight heartbeats, else suction might occur. The technique must be also robust against noises contaminated the feedback signal. Accordingly, this study also attentively examined the transient and steady state response of two different preload-based control implementations in the numerical model. The implementations were tested under both ideal (noise free) and noisy conditions at baseline to vigorous exercise as well as blood loss transitions. Proportional-integral-derivative (PID) and sliding mode controller (SMC) were the chosen controlling techniques, selected due to their popularity and robustness reputation. While at the noise free condition system measured PLVED was directly fed to the controller, the author contaminated the feedback signal with different levels of Gaussian white noises to realize the noisy condition. The results showed no significant difference between the two preload-based control implementations under ideal condition during all testing scenarios. Proceeding the tests showed that both PID and SMC delivered almost comparable performance at signal to noise ratio (SNR) of 15dB, although by increasing the noise level to 7dB PID finally failed at blood loss scenario and severely penetrated in the suction, indicated by persistent negative PLVED. On the contrary, SMC is the control strategy that not only could tolerate all the noise levels and never fell into the suction region, but also could maintain a reasonable level of hemodynamic parameters deviations comparably.
The last objective of this study was to develop an in-vitro evaluation protocol for control system utilizing a mock circulation loop (MCL) exploiting the same scenarios used in the second objective. The test showed that the devised scenarios were useful for evaluation of preload-based control. Observing the results showed the preload controller could again outperform the constant speed operational in all three scenarios, provided the impetus for further animal trials
Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) Cause Interstitial Nephritis: a case Report and Review of Literatures
No full textDrug Rash with Eosinophilia and Systemic Symptoms (DRESS) is a potentially life-threatening, complex, and multifaceted disease which may imitate other grave conditions. It presents with cutaneous drug eruptions, fever, hematologic abnormalities (an eosinophil count of 1500/mm3 or atypical lymphocytosis), and systemic involvement including hematologic, renal, pulmonary, hepatic, cardiac, gastrointestinal, neurologic, and endocrine abnormalities. Anticonvulsant therapies (mainly carbamazepine) are among the most important causative drugs.Case report: Herein we present a10-year-old girl who developed skin rash, systemic symptoms, marked eosinophilia, and kidney involvement following anticonvulsive treatment with phenobarbital and sodium valproate. She experienced multiple hospitalizations due to an improper diagnosis and management.Conclusion: Drug Induced Hypersensitivity Syndrome (DIHS) is a severe life-threatening disorder which mostly occurs due to aromatic anticonvulsive drugs. The disease may mimic other serious conditions and delay in the diagnosis and improper treatment may cause organ involvement and more severe outcomes.Key words: Drug Hypersensitivity Syndrome; DRESS Syndrome; Drug Reaction with Eosinophilia and Systemic Symptoms; Drug Eruptions; Interstitial Nephritis
Eosinophilic Cystitis and Interstitial Cystitis: may allergy be the reason?
No full text Allergic diseases have increased in prevalence during recent years. Although they impose numerous health and financial burden on patients and their family and also the society, they are to some extent preventable and manageable. While reviewing the literature to find any relationship between allergic disease as the familiar and preventable conditions and the two unfamiliar entities, named Eosinophilic Cystitis (EC) and Interstitial cystitis(IC); a significant number of reports were found about the etiological roll of atopy and allergy in the development of these conditions. Nevertheless this relationship is stronger concerning IC than EC. Referring to allergy as a contributing factor makes it more understandable and controllable. Although in order to reach a proper conclusion more thorough studies are required.Keywords: Interstitial Cystitis; Hypersensitivity; Atopic Hypersensitivity;Eosinophilia; Human; Urinalysis.
ehsan20e20e/CircularRR_AOPS: Datasets for "A deep learning method for empirical spectral prediction and inverse design of all-optical nonlinear plasmonic ring resonator switches" E. Adibnia, M. A. Mansouri-Birjandi, M. Ghadrdan and P. Jafari, Scientific reports (2024)
No full text<p></p>
<p>The datasets for the work presented in the research paper titled "A deep learning method for empirical spectral prediction and inverse design of all-optical nonlinear plasmonic ring resonator switches" will be published in <strong>Scientific reports</strong> (2024).
Corresponding author: [email protected]</p>
<p><strong>Full Changelog</strong>: https://github.com/ehsan20e20e/CircularRR_AOPS/commits/1</p>
A new full-Newton step O(n) infeasible interior-point algorithm for semidefinite optimization
No full textInterior-point methods for semidefinite optimization have been studied intensively, due to their polynomial complexity and practical efficiency. Recently, the second author designed a primal-dual infeasible interior-point algorithm with the currently best iteration bound for linear optimization problems. Since the algorithm uses only full Newton steps, it has the advantage that no line-searches are needed. In this paper we extend the algorithm to semidefinite optimization. The algorithm constructs strictly feasible iterates for a sequence of perturbations of the given problem and its dual problem, close to their central paths. Two types of full-Newton steps are used, feasibility steps and (ordinary) centering steps, respectively. The algorithm starts from strictly feasible iterates of a perturbed pair, on its central path, and feasibility steps find strictly feasible iterates for the next perturbed pair. By using centering steps for the new perturbed pair, we obtain strictly feasible iterates close enough to the central path of the new perturbed pair. The starting point depends on a positive number ?. The algorithm terminates either by finding an ?-solution or by detecting that the primal-dual problem pair has no optimal solution (X *,y *,S *) with vanishing duality gap such that the eigenvalues of X * and S * do not exceed ?. The iteration bound coincides with the currently best iteration bound for semidefinite optimization problems.Software TechnologyElectrical Engineering, Mathematics and Computer Scienc
Full-Newton step interior-point methods for conic optimization
No full textIn the theory of polynomial-time interior-point methods (IPMs) two important classes of methods are distinguished: small-update and large-update methods, respectively. Small-update IPMs have the best theoretical iteration bound and IPMs with full-Newton steps belong to this class of methods. Within each of these classes one has feasible and infeasible interior-point methods (IIPMs). In this thesis we first deal with full-Newton step IIPMs, and we consider feasible full-Newton step IPMs.Electrical Engineering, Mathematics and Computer Scienc
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