21 research outputs found
Impulsive Hyperbolic System of Partial Differential Equations of Fractional Order with Delay
No full textThis paper deals with the existence of solutions to impulsive partial hyperbolic differential equations with finite delay, involving the Caputo fractional derivative. Our results will be obtained using Krasnoselskii fixed point theorem
Rashist
No full textРозроблений доктором педагогічних наук, професором Піддячим Миколою Івановичем термін «Рашист (rashyst)» 27 липня 2022 року розміщений у соціальній мережі Facebook та на сайті електронної бібліотеки Національної академії педагогічних наук України (URL: https://lib.iitta.gov.ua/732038/). Він має на меті: 1) сприяти усвідомленню українцями і світовою спільнотою небезпечності для цивілізації значної кількості осіб із деформованим єством; 2) виокремлення в узагальнюючій особистісній характеристиці росіянина небезпечних для людства складових, що означені у терміні «рашист»; 3) врахування наявності критичної маси рашистів у процесі розроблення просторів доступних для сталого розвитку, а також комунікаційної стратегії міжособистісного та цивілізаційного характеру. Для глибшого усвідомлення небезпечності цього явища світовою спільнотою та необхідності спрямування колективних зусиль і ресурсів на шляху його «ізолювання» термін перекладений на: англійську, мандаринську китайську, хінді, іспанську, французьку, арабську, бенгалі, португальську, індонезійську, урду, німецьку, польську, італійську, японську, російську мови.
Рашист (rashyst) – це особа, що є прихильником рашизму. У її єстві сформований критично низький рівень свідомості, викликаний порушенням системи загальнолюдських цінностей, внаслідок: неналежного впливу материнської школи і родини на вікових етапах розвитку; низького рівня освіти і виховання у соціальних інституціях, спрямованих на гармонізацію психологічної сфери, соціалізацію та капіталізацію людського ресурсу в умовах реальної й прогнозованої трудової діяльності; відсутності внутрішньої потреби самовираження та самоствердження шляхом створення суспільно значущих духовних і матеріальних цінностей; системного неперервного впливу агресивно-войовничо налаштованого середовища; тривалого перебування у деградованому соціальному і культурному просторі тощо.The term “Rashist” (rashyst), developed by Doctor of Pedagogical Sciences, Professor Mykola Ivanovych Piddiachyi, was published on July 27, 2022, on the social media platform Facebook and on the website of the electronic library of the National Academy of Pedagogical Sciences of Ukraine (URL: https://lib.iitta.gov.ua/732038/). The term aims to: 1. Promote the awareness of Ukrainians and the global community about the threat posed to civilization by a significant number of individuals with a deformed nature; 2. Highlight, in the generalized personal characteristics of Russians, the dangerous components for humanity indicated by the term “Rashist”; 3. Take into account the existence of a critical mass of rashists when developing spaces for sustainable development and when considering communication strategies of an interpersonal and civilizational nature. For a deeper understanding of the danger posed by this phenomenon to the global community and the necessity of directing collective efforts and resources towards its “isolation”, the term has been translated into: English, Mandarin Chinese, Hindi, Spanish, French, Arabic, Bengali, Portuguese, Indonesian, Urdu, German, Polish, Italian, Japanese, and Russian.
Rashist is an individual who supports Rashism. Their nature is characterized by a critically low level of consciousness, caused by a disruption in the system of universal human values, as a result of: ● Inadequate influence of the maternal school and family during developmental stages; ● Low levels of education and upbringing in social institutions aimed at harmonizing the psychological sphere, socializing, and capitalizing human resources within the framework of real and predicted labor activity; ● The lack of an internal need for self-expression and self-assertion through the creation of socially significant spiritual and material values; ● Continuous and systematic influence of an aggressively militant environment; ● Long-term existence in a degraded social and cultural space, among other factors
The expression of metabolic genes in the liver of dams fed different proportions (10/73, 20/63 or 30/53%) of dietary protein/dietary carbohydrates (DP/DCH) during gestation and lactation.
No full text<p>(A) The relative mRNA levels of sterol regulatory element binding protein 1 (SREBP1), fatty acid synthase (FAS), and pyruvate kinase (PK). (B) A representative immunoblot of AMP-activated protein kinase (AMPK), threonine phosphorylation of AMP-activated protein kinase (P-AMPK), p70 S6 kinase (S6K), threonine phosphorylation of S6 kinase (P-S6K), fatty acid synthase (FAS) and actin. (C) Western blot densitometric analysis of FAS/ACTIN. (D) A representative histology picture of the liver of rats fed 10/73, 20/63 or 30/53% DP/DCH at day 5 of lactation. Western blot densitometric analysis of (E) P-S6K/S6K, (F) P-AMPK/AMPK. (G) The relative mRNA levels of serine dehydratase (SDH). Values are the mean ± SEM of three different blots. n = 5. **p<0.01, ***p<0.001.</p
Tests of mode-coupling theory in two-dimensions
No full textWe analyze the glassy dynamics of binary mixtures of hard disks in two dimensions. Predictions of the mode-coupling theory (MCT) are tested with extensive Brownian dynamics simulations.Measuring the collective particle density correlation functions in the vicinity of the glass transition, we verify four predictedmixing effects. For instance, for large size disparities, adding a small amount of small particles at a fixed packing fraction leads to a speedup in the long-time dynamics, while for small size disparities it leads to a slowing-down. Qualitative features of the nonergodicity parameters and the β relaxation, which both depend in a nontrivial way on the mixing ratio, are found in the simulated correlators. Studying one system in detail, we are able to determine its ideal MCT glass transition point as ϕc = 0.7948 and test MCT predictions quantitatively.publishe
Morphology of the assembled tissue and quantification of the sGAG in media during assembly.
No full text<p>MSC assembled tissues looked transparent whereas MSC+CD assembled tissues were more opaque and the day 0 MSC tissue was smaller than the rest of the assembled tissues. (A). The graph of sGAG in media during assembly of the MSC micropellets showed that the sGAG release to the media was diminished after assembly time points (B). The sGAG in media for the MSC+CD assembled tissues showed a decreasing trend in the first week, which is mostly the sGAG originating from CD (C). Abbreviations: MSC, cell only control; MSC+CD, composite (cell and cartilage dust); d0, day 0; d4, day 4; d7, day 7; d10, day 10; d14, day 14. Scale bar: 1 mm.</p
Gene expression analysis of MSC and MSC+CD macro and micropellets at day 7 and 14.
No full text<p>Aggrecan (A), Versican (B), SOX9 (C), RUNX2 (D), Collagen II (E), Collagen I (F), Collagen X (G) and Osteocalcin (H) gene expressions were analyzed to assess the chondrogenic, hypertrophic and osteogenic characteristics of the generated macro and micropellets. Abbreviations: MSC, cell only control; MSC+CD, composite (cell and cartilage dust); macro, macropellet; micro, micropellet; d7, day 7; d14, day 14.</p
Cartilage dust (CD) characterization and micropellet morphology.
No full text<p>Phase contrast image of CD demonstrated a gradient in particles size (A). The particles size distribution indicated that most of the particles had a size smaller than 10 μm and the average particle size was estimated to be 5.53 μm (B). Phase contrast images of MSC and MSC+CD micropellets on day 1 and 14 and macroscopic images of MSC and MSC+CD macropellets (C), the average diameters for MSC micropellets on day 1 was 100.8 ± 7.8 μm and on day 14 was 82.6 ± 10.8 μm, the average diameters for MSC+CD micropellets on day 1 was 176.1 ± 9.9 μm and on day 14 was 183.8 ± 16.2 μm Overall, MSC+CD macro and micropellets were greater in size. Abbreviations: MSC, cell only control; MSC+CD, composite (cell and cartilage dust). Scale bars: 500 μm.</p
Histological assessment of MSC and MSC+CD macro and micropellets at day 14.
No full text<p>The alcian blue staining demonstrated that MSC+CD macropellet was less intact when compared to MSC macropellet. Collagen II staining was stronger in MSC+CD macro and micropellets when compared to MSC macro and micropellets indicating that CD itself contained high quantity of collagen II. Collagen X staining was similar in all conditions. All the images were overlayed with DAPI staining. Abbreviations: MSC, cell only control; MSC+CD, composite (cell and cartilage dust); macro, macropellet; micro, micropellet. Scale bars: 100 μm.</p
Histological assessment of the assembled tissues.
No full text<p>Alcian blue staining showed inefficient integration of the CD particles in day 0 MSC+CD assembly (equivalent to MSC+CD macropellets) and decreasing integration efficiency was observed when the assembly day increased. Collagen II staining confirmed that the quantity of collagen II in MSC+CD assembled tissues was higher than the collagen II in MSC assembled tissues. Abbreviations: MSC, cell only control; MSC+CD, composite (cell and cartilage dust); d0, day 0; d4, day 4; d7, day 7; d10, day 10; d14, day 14. Scale bars: 100 μm.</p
