1,721,126 research outputs found
Atypical neurological disorders in an elderly man with liver cirrhosis
No full textAHD is a rare complication of liver cirrhosis that can be apperaed also in the absence of clinical and radiological findings of portosystemic shunt. In the presence of movement disorders in a cirrhotic patient, the AHD should be excluded because the clinical evolution and treatment differ from other conditions such as hepatic encephalopathy or movement disorders in advanced liver disease. Due to atypical and heterogeneous clinical manifestation, the MRI plays a key role in the diagnosis of this condition
The BondMachine, a moldable computer architecture
No full textFuture systems will be characterized by the presence of many computing core in a single device, on large scale data centers or even at the level of IoT devices. The ability to fully exploit computational architectures’ heterogeneity and concurrency will be a key point. In this manuscript we present the BondMachine (BM), an innovative prototype software ecosystem aimed at creating facilities where hardware and software are co-designed, guaranteeing a full exploitation of fabric capabilities (both in terms of concurrency and heterogeneity) with several hardware optimization possibilities. The fundamental innovation of the BM is to provide a new kind of computer architecture, where the hardware dynamically adapts to the specific computational problem rather than being static and generic, as in standard CPUs synthesized in silicon. Hardware can be designed to fit precisely any computational task needs, implementing only the processing units needed and discarding generic solutions. By using BMs within FPGA technologies end-to-end solutions could be realized, in which the creation of domain-specific hardware is part of the development process as much as the software stack. FPGA technology allows to create independent processing units on a single low-power board, and to design their interconnections “in silicon” to maximally fit the design needs. The processors of the BMs are suitable for computational structures like neural networks and tensor processing models. Machine Learning (ML) and Deep Learning (DL) popularity keeps increasing in scientific and industrial areas
Vertically integrated CMOS active pixel sensors for tracking applications in HEP experiments
No full textn this work we propose an innovative approach to particle tracking based on CMOS Active Pixel Sensors layers, monolithically integrated in an all-in-one chip featuring multiple, stacked, fully functional detector layers capable to provide momentum measurements (particle impact point and direction) within a single detector. This will results in a very low material detector, thus dramatically reducing multiple scattering issues. A first chip prototype has been fabricated within a multi-project run using a 130nm CMOS 3D Chartered/Tezzaron technology, featuring two layers bonded face-to-face. Tests have been carried out on full 3D structures, providing the functionalities of both tiers and their inter-communications. Actually, laser scans have been carried out using highly focussed spot size, obtaining coincidence responses of the two layers. X-rays sources have been used as well for sensor calibration purposes. Beam tests with 3MeV protons have been carried out at the INFN LABEC laboratories in Florence (Italy) to assess the suitability of the proposed approach for Minimum Ionizing Particle detection
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Effects of systemic prostaglandin E1 on splanchnic and peripheral haemodynamics in control subjects and in patients with cirrhosis
No full textProstaglandins of the E series showed metabolic and clinical effects in patients with liver disease; changes in splanchnic haemodynamics might be involved. Blood flow in femoral and mesenteric artery and in the portal vein was measured by echo-Doppler in 10 controls and 14 cirrhotic patients, in response to the systemic infusion of a PGE1 analogue (30 μg/h for 2-6 h) or saline, performed in random order. Intraparenchymal resistive and pulsatility indices in the liver, spleen and kidney were also measured. In both groups PGE1 increased femoral artery flow by 40%, irrespective of infusion time. Heart rate increased slightly, whereas mean arterial pressure decreased. There were no changes in mesenteric artery and portal vein flow, as well as in resistance indices. Saline infusion increased femoral artery flow by 4%. PGE1 infusion does not produces significant effects on Doppler-assessed splanchnic hemodynamics in controls and in cirrhotic patients, in spite of significant effects on peripheral circulation
Natural History of cirrhotic patients with small esophageal varices: a prospective study
No full textIF = 3.95
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