908 research outputs found

    Troponin T release is associated with silent myocardial ischaemia in black men: The SABPA Study

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    Background High sensitivity cardiac troponin T (hs-cTnT) is a validated marker of myocardial damage and may reflect the degree of silent myocardial ischaemia (SMI) and ventricular strain. Our aim was to compare hs-cTnT levels in black and white South Africans taking SMI into consideration. We further explored the capability of hs-cTnT to predict the presence of compensatory systolic hypertension in this South African cohort. Methods A bi-ethnic sex cohort (n = 404) with similar socioeconomic status (198 black participants and 206 white participants, aged 20–65 years) participated in this target population study where 24 h ambulatory blood pressure, electrocardiogram and overnight fasting cardiometabolic variables were measured. Results Hypertension, higher glycated haemoglobin levels and more frequent and longer SMI events were observed more often in the black participants. Multivariate linear regression analysis showed positive associations between SMI events [Adj. R2 = 0.19; β 0.35 (0.08–0.62); p < 0.01], SMI event maximum duration [Adj. R2 = 0.17, β 0.43 (0.16–0.70), p < 0.01], SMI total duration [Adj. R2 = 0.12; β 0.37 (0.10; 0.65), p = 0.05] and hs-cTnT in black males only.] A lower hs-cTnT cut-point ≥4.2 pg/ml for 24 h systolic hypertension was predicted in the black participants compared with ≥5.6 pg/ml in the white participants (area under the curve 0.66–67 (95% CI: 0.57–0.75), p < 0.001) with a respective sensitivity/specificity of 64/68% and 61/71%. Conclusions hs-cTnT may be a potential marker of SMI in the prediction of systolic blood pressure increases, as well as clusters of risk factors for cardiovascular disease. Ethnic- and possibly sex-specific references values for hs-cTnT should be considered for risk stratificatio

    Silent ischemia is associated with subclinical atherosclerosis in African males: the sympathetic activity and ambulatory blood pressure in Africans study

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    Silent myocardial ischemia is a predictor of subclinical atherosclerosis driven by increased cardiovascular risk markers, although still unknown in Africans. The aim of this study was to assess if cardiovascular risk markers will be associated with subclinical atherosclerosis. African men were stratified into (i) 24-hour silent ischemia (SI, n = 38) and (ii) without (nSI, n = 40) groups. Ambulatory blood pressure (BP), SI, 12-lead resting electrocardiogram, ultrasound carotid intima-media thickness (CIMT) measurements, and fasting blood samples were obtained. Above-normal cardiovascular risk markers, that is, glucose level, heart rate, BP, and CIMT, were evident in men with SI. Hypertension prevalence was 89% in the African SI men as opposed to 64% in the nSI men. Regression analyses revealed that only SI events in SI men explained 35% (95% confidence interval [CI]: 0.22;0.52) of the variance in CIMT, while in all African men it explained 29% (95% CI: 0.19;0.39). In conclusion, SI was associated with structural vascular disease in African men. This could imply that SI is not necessarily driven by hypertension in African men but through other possible mechanisms such as increased sympathetic nervous system activity

    Book Review: Co-Intelligence: Living and Working with AI

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    Author: Ethan Mollick Reviewed by Lieutenant Colonel Zachary E. Griffiths, Special Assistant to the Chief of Staff of the Army Zachary E. Griffiths’ review of Co-Intelligence: Living and Working with AI, portrays Ethan Mollick’s book as a concise, easy-to-read tour of artificial intelligence—a user’s guide of sorts. With insightful information about how to use AI, Mollick’s work also covers the history of artificial intelligence and ethical and legal issues that come with using large language models. In his review, Griffiths recommends all Army officers read this book. ©2025 Zachary E. Griffithshttps://press.armywarcollege.edu/parameters_bookshelf/1079/thumbnail.jp

    The Alysiinae (Hym. Braconidae) parasites of the Agromyzidae (Diptera). VII Supplement.

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    Zusätzliche Informationen aus der Sammlung europäischer Alysiinae (haupsächlich Dacnusini) des Autors werden veröffentlicht aus Anlaß der Übergabe dieser Sammlung an das British Museum (Natural History). Zehn neue Arten werden beschrieben, zwei in Dacnusa Haliday (D. arctica spec. nov. und D. euphrasiella spec. nov.), drei in Exotela Förster (E. viciae spec. nov., E. lathyri spec. nov. und E. chromatomyia spec. nov.) und fünf in Chorebus Haliday (C. galii spec. nov., C. rostratae spec. nov., C. chenopodii spec. nov., C. claripennis spec. nov. und C. eucodonis spec. nov.). Chorebus stenocentrus (Thomson) wird neu beschrieben.Nomenklatorische Handlungenchenopodii Griffiths, 1984 (Chorebus), spec. n.claripennis Griffiths, 1984 (Chorebus), spec. n.eucodonis Griffiths, 1984 (Chorebus), spec. n.galii Griffiths, 1984 (Chorebus), spec. n.rostratae Griffiths, 1984 (Chorebus), spec. n.stenocentrus (Thomson, 1895) (Chorebus), comb. n. hitherto Dacnusa (Dacnusa) stenocentraarctica Griffiths, 1984 (Dacnusa), spec. n.cerpheres (Nixon, 1948) (Dacnusa), comb. n. hitherto Rhizarcha cerphereseuphrasiella Griffiths, 1984 (Dacnusa), spec. n.chromatomyiae Griffiths, 1984 (Exotela), spec. n.lathyri Griffiths, 1984 (Exotela), spec. n.viciae Griffiths, 1984 (Exotela), spec. n.Supplementary information from the author´s collection of European Alysiinae (mainly Dacnusini) is here published on the occasion of the deposition of that collection in the British Museum (Natural History). Ten new species are described, two in Dacnusa Haliday (D. arctica spec. nov. and D. euphrasiella spec. nov.), three in Exotela Förster (E. viciae spec. nov., E. lathyri spec. nov. and E. chromatomyia spec. nov.), and five in Chorebus Haliday (C. galii spec. nov., C. rostratae spec. nov., C. chenopodii spec. nov., C. claripennis spec. nov. and C. eucodonis spec. nov.). Chorebus stenocentrus (Thomson) is redescribed.Nomenclatural Actschenopodii Griffiths, 1984 (Chorebus), spec. n.claripennis Griffiths, 1984 (Chorebus), spec. n.eucodonis Griffiths, 1984 (Chorebus), spec. n.galii Griffiths, 1984 (Chorebus), spec. n.rostratae Griffiths, 1984 (Chorebus), spec. n.stenocentrus (Thomson, 1895) (Chorebus), comb. n. hitherto Dacnusa (Dacnusa) stenocentraarctica Griffiths, 1984 (Dacnusa), spec. n.cerpheres (Nixon, 1948) (Dacnusa), comb. n. hitherto Rhizarcha cerphereseuphrasiella Griffiths, 1984 (Dacnusa), spec. n.chromatomyiae Griffiths, 1984 (Exotela), spec. n.lathyri Griffiths, 1984 (Exotela), spec. n.viciae Griffiths, 1984 (Exotela), spec. n

    A Systematic Review of Online Sex Addiction and Clinical Treatments Using CONSORT Evaluation

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    Researchers have suggested that the advances of the Internet over the past two decades have gradually eliminated traditional offline methods of obtaining sexual material. Additionally, research on cybersex and/or online sex addictions has increased alongside the development of online technology. The present study extended the findings from Griffiths’ (2012) systematic empirical review of online sex addiction by additionally investigating empirical studies that implemented and/or documented clinical treatments for online sex addiction in adults. A total of nine studies were identified and then each underwent a CONSORT evaluation. The main findings of the present review provide some evidence to suggest that some treatments (both psychological and/or pharmacological) provide positive outcomes among those experiencing difficulties with online sex addiction. Similar to Griffiths’ original review, this study recommends that further research is warranted to establish the efficacy of empirically driven treatments for online sex addiction

    Harry Potter and the paradox of the ‘expert’

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    In this article, Dominic Griffiths reflects upon the current cultural gapbetween those who locate themselves as working ‘on the inside’ of the worldof ‘special educational needs’ and the ‘inclusion movement’ and those whomight be describe as ‘mainstream classroom teachers’. Griffiths warns of thedangers of the dangers of ‘enculturation’ of the ‘insiders’ which can lead tocommunal visions of mainstream teachers as ‘barriers to inclusion’. Equally,from ‘outsider’ perspectives, the world of special and inclusive education maybe perceived as ‘mysterious’, hidden in a fog of arcane acronyms and popu-lated by specialist ‘experts’. The author calls for a conscious demystificationof this world and an active reaching out to and nurturing of mainstream col-leagues without whom, he argues, the inclusion project cannot succeed

    E-book : &#34;realism, Idealism And International Politics&#34; (author : Martin Griffiths)

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    TEORI HUBUNGAN INTERNASIONAL Buku yang sangat baik dibaca untuk yang ingin mendalami Teori Hubungan Internasional. Griffiths mengupas secara mendalam teori-teori realisme dari pemikir terkemuka HI mulai dari Hans Morgenthau, Kenneth Waltz, hingga Hedley Bull. E-BOOK ini Gratis..., SILAHKAN DI DOWNLOAD

    Interactive television quizzes as gambling: a cause for concern?

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    Recently, there has been a significant increase in the number of UK television shows in which viewers call into the show using a premium-rate telephone service. At one level it could be argued that in these instances viewers are participating in a lottery. Viewers are typically asked to call a premium-rate telephone line to answer a simple question. Winners are then chosen from all those viewers with the correct answer. It could also be argued that the viewer is staking money (i.e., the cost of the premium-rate telephone call) on the outcome of a future event (i.e., whether they will get the correct answer). This again could be defined as a form of gambling. Interactive television quiz shows share many of the dimensions of interactive television gambling and also raise the same concerns about vulnerable and susceptible populations. These concerns are discussed

    Reconciling Versioning and Context in Hypermedia Structure Servers

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    Contextual structure servers and versioning servers share a similar goal in allowing different views on a stored structure according to the viewer’s perspective. In this paper we argue that a generic contextual model can be used to facilitate versioning. In order to prove our hypothesis we have drawn on our experiences with OHP-Version to extend FOHM’s contextual model

    Author Correction: Immediate neural impact and incomplete compensation after semantic hub disconnection (Nature Communications, (2023), 14, 1, (6264), 10.1038/s41467-023-42088-7)

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    \ua9 2023, The Author(s).Correction to: Nature Communications, published online 07 October 2023 In this article Thomas E. Cope, Timothy D. Griffiths, Matthew A. Howard III and Christopher I. Petkov should have been denoted as equally contributing joint senior authors. The original article has been corrected
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