102 research outputs found
Aḥmad of Niğde's al-Walad al-Shafῑq and the Seljuk past
No full textThe unpublished unique manuscript of the 14th century Persian work known as al-Walad al-Shafiq (‘The Compassionate Child’) held in the Süleymaniye Library in Istanbul has hitherto never been studied in detail, although it is of considerable importance as a source for medieval Anatolia. This article assesses al-Walad al-Shafiq in the context of the Persian historiography of Anatolia and the historical milieu in which it was composed, arguing that the work is characterised by a sense of loyalty to the vanished Seljuk dynasty that ruled much of Anatolia from the late 11th to the early 14th century. I also examine such information as has survived about the life and background of its author, Qāḍῑ, Aḥmad of Niğde, and consider why the work was written and for whom.</p
Interview with Hossn Shah
No full textمقابلة مع الكاتبة، الصحفية، المخرجة والنسوية المصرية حسن شاه عن فيلمها "أريد حلا" وكيف تعتقد أن السينما المصرية النسوية يمكن أن تعالج القضايا الاجتماعية. كما تناقش تجاربها مع النقاد ومشاريعها القادمة. قامت بالمقابلة نوال شفيق.An interview with Egyptian feminist, author, journalist and film director, Hossn Shah about her film "Ored Halan (I Want A Solution)" and how Egyptian cinema can address feminist issues. Additionally, she discusses her experiences with different art critics. The interview was conducted by Nawal Shafiq
Community Engagement Practices at Research Centers in U.S. Minority Institutions: Priority Populations and Innovative Approaches to Advancing Health Disparities Research
No full textThis paper details U.S. Research Centers in Minority Institutions (RCMI) Community Engagement Cores (CECs): (1) unique and cross-cutting components, focus areas, specific aims, and target populations; and (2) approaches utilized to build or sustain trust towards community participation in research. A mixed-method data collection approach was employed for this cross-sectional study of current or previously funded RCMIs. A total of 18 of the 25 institutions spanning 13 U.S. states and territories participated. CEC specific aims were to support community engaged research (94%); to translate and disseminate research findings (88%); to develop partnerships (82%); and to build capacity around community research (71%). Four open-ended questions, qualitative analysis, and comparison of the categories led to the emergence of two supporting themes: (1) establishing trust between the community-academic collaborators and within the community and (2) building collaborative relationships. An overarching theme, building community together through trust and meaningful collaborations, emerged from the supporting themes and subthemes. The RCMI institutions and their CECs serve as models to circumvent the historical and current challenges toresearch in communities disproportionately affected by health disparities. Lessons learned from these cores may help other institutions who want to build community trust in and capacities for research that addresses community-related health concerns
The role of AP-1 proteins in the transforming growth factor-beta signaling pathway in prostate cancer, 2005
No full textTransforming growth factor-beta (TGF-?) has a variety of roles including cell growth inhibition, stimulation of proliferation, differentiation, apoptosis and extracellular matrix (ECM) formation. TGF-? inhibits growth of the epithelial cells in the prostate gland. The ability of TGF-? to inhibit cell growth enables it to act as a potent tumor suppressor. Here, we show that TGF-? has different effects on proliferation in DU145 (TGF-?- responsive) and PC3M (TGF-? - resistant) prostate cancer cell lines. RT-PCR analysis and Real-time PCR data have determined the varying levels of AP-1 family members in both cell lines. In PC3M and DU145 cells, we have shown that TGF-p exerts opposite effects on JunD, cFos and Fra2 expression, suggesting that AP-1 family members may be involved in the differential effects of TGF-? in these cell lines. The present observation confirms an intact inhibitory role of TGF-? on proliferation in DU145 cells, and shows a non-inhibitory function in PC3M cell growth. In PC3M cells TGF-? may exert effects leading to the metastatic nature of this cell line
خرم علی شفیق کی تصنیف ’’اقبال کی منزل‘‘ کا تنقیدی مطالعہ
No full textIqbal ki Manzil is a biography of Allama Iqbal compiled by Khuram Ali Shafiq. According to Author, this is first authentic biography written on Allama Iqbal’s life based on documents. Earlier, Iqbal’s biographers did not follow this principal. The author has previously worked on a project to write a five-volumes book on Iqbal’s biography, three of which have been published from Iqbal Academy, Lahore. It is as if the author is denying the authenticity of his previous work by making this claim. But when we look at the list of sources in this book, we found almost the same sources which other biographers also used. This article consists of critical study of this book which show how true the author in his claim.
Measurement of circumsolar ratio in high dust loading regions using a photographic method
No full textPreparation of polyurethane foams using liquefied oil palm mesocarp fibre (OPMF) and renewable monomer from waste cooking oil
No full textNrf2 deficiency influences susceptibility to steroid resistance via HDAC2 reduction
No full textAbnormal lung inflammation and oxidant burden are associated with a significant reduction in histone deacetylase 2 (HDAC2) abundance and steroid resistance. We hypothesized that Nrf2 regulates steroid sensitivity via HDAC2 in response to inflammation in mouse lung. Furthermore, HDAC2 deficiency leads to steroid resistance in attenuating lung inflammatory response, which may be due to oxidant/antioxidant imbalance. Loss of antioxidant transcription factor Nrf2 resulted in decreased HDAC2 level in lung, and increased inflammatory lung response which was not reversed by steroid. Thus, steroid resistance or inability of steroids to control lung inflammatory response is dependent on Nrf2-HDAC2 axis. These findings have implications in steroid resistance, particularly during the conditions of oxidative stress when the lungs are more susceptible to inflammatory response, which is seen in patients with chronic obstructive pulmonary disease, asthma, rheumatoid arthritis, and inflammatory bowel disease
Dynamic composition and management of emergency response processes
No full textThe number of disasters, whether human-made or natural, has been on the rise over in the recent years; they have destroyed lives, homes, and caused widespread damage to infrastructure. The increase in disasters means there is also a higher demand for efficient response planning. Effective emergency response planning requires communication and coordination with the diverse operational systems belonging to various collaborating government agencies, non-government organizations (NGOs), and private sector entities. An essential requirement for developing an emergency response process is to establish information sharing and system-level interoperability among the operational systems of collaborating organizations. The challenge is that emergency response processes are not well-structured and do not have a well-defined outcome; they are knowledge-centric. Their workflow structure and execution may evolve dynamically based on the environmental context and the type of service or activity invoked during process execution. It is impractical to define static plans and response process workflows for every possible situation since unforeseeable situations may arise. Thus, a dynamic response requires adaptability to a changing situation as an incident evolves.
In this thesis, we develop an iterative end-to-end solution for the dynamic composition and management of an Emergency Response Management System, called Dynamic Emergency Response Processes System (DERPS). DERPS allows the Incident Commander to develop a contextualized response using ontology-based reasoning and allows its dynamic adaptation to situational changes. We also adapt and apply DERPS in the COVID-19 context. Specifically, given the pandemic’s scale and scope, home-based isolation has been considered a potential first step to reduce the spread of the virus and limit the stress on the healthcare system. However, home-based isolation needs and requirements are unique for each patient. We show how DERPS can be utilized to develop personalized patient care plans to ensure that each patient’s needs are appropriately met while they are confined to their home. We develop a prototype implementation to show the feasibility of the proposed framework and discuss challenges and issues in deploying such a system in practice.Ph.D.Includes bibliographical reference
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