1,721,149 research outputs found
L’identità di un ragazzo: analisi della formazione delle maschilità attraverso il romanzo-indagine Faire le Garçon di Jérôme Meizoz
No full textA partire dagli anni ’80 l’attenzione sulla costruzione delle maschilità è divenuta sempre più oggetto di indagine da un punto di vista prettamente scientifico e in seguito anche oggetto di interesse anche per la produzione letteraria. Ne è un esempio il romanzo Faire le Garçon, scritto da Jérôme Meizoz, che, grazie alla sua struttura bipartita che comprende il romanzo vero e proprio e delle indagini, riesce ad esaminare la costruzione delle maschilità e a narrare nuovi modi di pensare al maschile. Partendo da questo romanzo peculiare, questo articolo avrà come oggetto l’analisi del modo in cui ragazzi costruiscono la loro identità, spinti per lo più da visioni pseudoscientifiche e inaccurate sul genere, svelando i problemi di una visione del maschile troppo rigida e legata a un immaginario violento e mostrando la volontà sempre maggiore dei ragazzi di staccarsi da essa, per cercare nuovi modi per costruire la loro identità maschile
Histopathology of the gut in rheumatic diseases
Full text linkThe gastrointestinal tract regulates the trafficking of macromolecules between the environment and the host through an epithelial barrier mechanism and is an important part of the immune system controlling the equilibrium between tolerance and immunity to non-self-antigens. Various evidence indicates that intestinal inflammation occurs in patients with rheumatic diseases. In many rheumatic diseases intestinal inflammation appears to be linked to dysbiosis and possibly represents the common denominator in the pathogenesis of different rheumatic diseases. The continuative interaction between dysbiosis and the intestinal immune system may lead to the aberrant activation of immune cells that can re-circulate from the gut to the sites of extraintestinal inflammation as observed in patients with ankylosing spondylitis. The exact contribution of genetic factors in the development of intestinal inflammation in rheumatic diseases needs to be clarified
Pathogenesis of polymyalgia rheumatica
Full text linkPolymyalgia rheumatica (PMR) is a chronic, inflammatory disorder of unknown cause, almost exclusively occurring in people aged over 50 and often associated with giant cell arteritis. The evidence that PMR occurs almost exclusively in individuals aged over 50 may indicate that age-related immune alterations in genetically predisposed subjects contribute to development of the disease. Several infectious agents have been investigated as possible triggers of PMR even though the results are inconclusive. Activation of the innate and adaptive immune systems has been proved in PMR patients as demonstrated by the activation of dendritic cells and monocytes/macrophages and the altered balance between Th17 and Treg cells. Disturbed B cell distribution and function have been also demonstrated in PMR patients suggesting a pathogenesis more complex than previously imagined. In this review we will discuss the recent findings regarding the pathogenesis of PMR
Gut-derived CD8+ tissue-resident memory T cells are expanded in the peripheral blood and synovia of SpA patients
Full text linkCurrent evidence that exercise can increase the number of adult stem cells
No full textThe number of adult stem cells (ASCs) is very small, limiting the regenerative potential of tissues. One of the most studied ASCs in humans is the satellite cell (SC), which proliferates and increases pool size under exercise stress and muscle damage. This review examines the growth factor response to specific types of exercise to show the potential of exercise to stimulate not only SC self-renewal, but also other ASCs. We postulate that the same factors that stimulate a high proliferation of SCs in skeletal muscle after physical exercise should also stimulate the proliferation of ASCs in the tissue in which they reside, such as heart, bone, liver and etc. Regular exercise should be promoted, not only for disease prevention, but to maintain a high ASCs reserve and progenitor cell potential for rapid activation in response to future stressors and damage. © 2012 Springer Science+Business Media B.V
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
INTERNET OF MEDICAL THINGS (IOMT) AND INTEGRATED HOME ASSISTANCE
No full textThis article furnishes an overview of the actual IoT technology used in integrated home assistance. It delineates how the IoMT devices are improving the implementation of integrated home assistance services, and how the IoT technology can influence the global healthcare assistance in upcoming years aiding healthcare systems by supplying secure and effective cures in a complementary or alternative way, even during periods of crisis or health epidemics, like that of "COVID-19." Healthcare assistance based on IoT and the use of deep machine learning can in fact help healthcare workers by giving them new and improved diagnostic capabilities. The combination of machines and clinical experience improves the reliability of the services of integrated home assistance. Artificial intelligence and deep learning can also optimize disease management, provide large amounts of data, and generate analytics from IoMT devices. Transforming the delivery of integrated home assistance healthcare services in this way, thanks to IoT, is essential for improving self-management for people with chronic illnesses and providing specialized care for people located far away or at home
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