1,721,119 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Endometriosis in Monozygotic and Dizygotic Twins: A Review of Literature
No full textEndometriosis is a common estrogen-dependent inflammatory disease and a major contributor to pelvic pain and
subfertility in women of reproductive age. Its etiology and pathogenesis are not well known yet, but different studies
had highlighted its multifactorial nature, influenced by both genetic and environmental components. This minireview
analyzes the prevalence of the disease and the concordance for the presence and stage of endometriosis
in monozygotic (MZ) and dizygotic (DZ) twins. A higher concordance for the presence of the disease in MZ twins
rather than DZ twins was observed, with a statistically significant difference (p-value < 0.05). Only one study had
evaluated the concordance for endometriosis stage within MZ twins, observing a high rate of concordance. Genetic
component seems to play a pivotal role in the development of endometriosis and its severity
Endometriosis: Novel models, diagnosis, and treatment
Full text linkEndometriosis remains a cause of significant morbidity in
reproductive-aged women resulting in pelvic pain, pelvic
masses, and infertility. Endometriosis is defined as the presence
of endometrial glands and stroma outside of their normal
intrauterine location, most commonly in the dependent
portions of the pelvis. Endometriosis is treated with medical
therapies, surgery or both.Themedical therapies include oral
contraceptive pills, progestins, gonadotropin releasing hormone
analogues, and danazol. All of these medical therapies
induce a hormonal steady state that results in an environment
not conducive to the growth of endometriosis. Surgical therapies
for endometriosis-associated pain include the removal
of endometriotic implants and adhesions with restoration
of normal anatomy. Laparoscopy is an effective surgical
approach with the goal of excising visible endometriosis.
Since endometriosis is a chronic condition, it is not uncommon
for recurrences to occur. While endometriosis remains
an enigmatic disease, the introduction of new pharmacologic
agents and newer endoscopic methods of surgical treatment
has facilitated and improved the overall management of this
disease.
This special issue contains some papers that refer to
molecular and cellular mechanisms of endometriosis physiopathology
and some papers that refer to biomarker development
for improved early diagnosis and risk of disease,
while the other papers refer minimally to invasive treatment
for endometriosis and new medical therapies. Finally, there
are somemanuscripts about prevention of endometriosis and
novel models in endometriosis research
Role of laparoscopic hysterectomy in the management of endometrial cancer.
No full textPURPOSE OF REVIEW: By the current review we aim to describe different options for laparoscopic hysterectomy in patients with endometrial cancer and discuss the reported risk factors and limitations of laparoscopic hysterectomy in surgical staging of endometrial cancer.
RECENT FINDINGS: Laparoscopic techniques and equipment have matured over the last 15 years and are now widely used to treat patients with endometrial cancer, thereby potentially reducing perioperative morbidity and postoperative pain, and providing shorter hospital stay, faster recovery and improved quality of life compared with the corresponding open procedures. However, some risk factors are postulated to limit the use of laparoscopic hysterectomy in staging of endometrial cancer.
SUMMARY: Surgical staging of endometrial cancer by laparoscopic hysterectomy is feasible and well tolerated. This surgical approach does not seem to affect recurrence and overall survival rates. Limitations of laparoscopic hysterectomy in management of endometrial cancer need to be evaluated
Unicornuate uterus with noncommunicating functional horn: diagnostic workup and laparoscopic horn amputation
No full textObjective: To describe the diagnosis and the management of hematometra in a patient with unicornuate uterus with noncommunicating functional horn (hemi uterus and rudimentary uterine hemicavity). Design: Video case report. Setting: Minimally invasive gynaecology unit. Patient(s): Sixteen-year-old nulliparous woman admitted to the gynaecologic emergency department with pelvic pain during menses. Intervention(s): Two-dimensional transvaginal ultrasound, magnetic resonance imaging, and laparoscopic rudimentary horn resection. Main Outcome Measure(s): Description of a case of anomaly of the female reproductive tract treated by laparoscopy. Result(s): After pain reduction and stabilization of clinical condition, ultrasound and magnetic resonance were performed, which detected a hemi uterus with a right rudimentary uterine hemicavity and a hematosalpinx. The removal of the right rudimentary uterine horn was successfully performed. The patient was in good health at the 3-month follow-up visit. Conclusion(s): Laparoscopic amputation of a functional rudimentary horn is considered the basic and traditional surgical option for women with hemiuterus. A detailed diagnostic evaluation should be performed to avoid misdiagnoses of other anomalies with blind hemicavity, which may be treated by hysteroscopy. Laparoscopic surgery with minimally invasive approach could be an essential tool to treat these cases, achieving optimal results with low postsurgical pain and a short hospital stay
Deep Infiltrating Endometriosis and Spontaneous Hemoperitoneum: A Life-Threatening Situation Treated by Laparoscopy
No full textObjective: To describe a case of spontaneous hemoperitoneum in a woman affected by deep infiltrating endometriosis (DIE). Design: Technical video showing laparoscopic management of a spontaneous hemoperitoneum in a patient with DIE. Setting: Minimally Invasive Gynecological Unit, Sant'Orsola Academic Hospital, Bologna, Italy. Intervention: A 35-year-old nulliparous woman was admitted to our gynecologic emergency room because of pelvic pain and a fainting sensation. She had a history of DIE and had been followed for 6 months by our outpatient clinics. The patient underwent an immediate laparoscopy because of the rapid worsening of clinical conditions. After blood suction and difficult adhesiolysis, a vascular lesion with a huge blood flow, close to the left utero-ovarian ligament, was detected. Selective coagulation was performed with good results. During the follow-up visit after 1 month, the patient reported good health. Written informed consent was obtained from the patient for publication of this case report. Conclusion: Spontaneous hemoperitoneum represents a rare and life-threatening complication associated with endometriosis. In patients with hemoperitoneum and a history of endometriosis, it is important to pay attention to the possible presence of uncommon bleeding localizations. Laparoscopy was useful and effective in this challenging situation, identifying the bleeding source and performing selective coagulation
Innovative Cadaveric Technique: Utilising n-Butyl Cyanoacrylate (n-BCA) for Deep Endometriosis Excision Simulation in Minimal Invasive Surgery Training
No full textBackground: Our study aimed to create a novel technique using n-butyl cyanoacrylate (n-BCA) for minimal access simulation training on cadavers in deep endometriosis excision. Objectives: A step-by-step video demonstration of using n-BCA in cadavers to simulate deep endometriosis. This technique is integrated into training sessions using cadavers aimed at enhancing surgical proficiency for deep endometriosis procedures. Material and methods: Video article describing using n-BCA in cadavers as a simulation model. Result: This technique has been used in a hands-on cadaveric training course, and positive feedback supports the recommendation to incorporate this technique. Conclusion: Utilizing a human cadaver model proves beneficial for enhancing understanding of deep pelvic innervation. Implementing n-BCA in these cadaver dissections demonstrates both reproducibility and safety. This approach significantly contributes to refining surgical expertise in the excision of deep infiltrating endometriosis
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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