1,720,963 research outputs found
DNA binding and transactivation activity of A-myb, a c-myb-related gene.
A partial-length A-myb complementary DNA recently cloned by low-stringency hybridization with a c-myb probe to complementary DNA libraries derived from human cell lines showed a high degree of homology with the DNA-binding domain of c-myb and B-myb, suggesting that A-myb also encoded a DNA-binding protein. We report here the sequence of the entire coding region of A-myb complementary DNA and show that the full-length GST-A-myb fusion protein or a truncated derivative corresponding only to the putative DNA-binding domain interacts specifically with Myb-binding sites of the c-myb responsive promoters, MIM-1 and CD34. In transient transfection assays, A-myb transactivated the bound promoters. These results suggest that, analogous to the other members of the Myb family, the A-myb gene encodes a bona fide transactivator. The distinct function of A-myb might derive from its pattern of expression and/or its relative potency as a transactivator of myb target genes
Latest Frasnian Atrypida (Brachiopoda) from South China
In South China latest Frasnian (Palmatolepis linguiformis Zone) the representatives of the order Atrypida (Brachiopoda) are most common in central Hunan Province. They are relatively rare in other parts of South China due to unfavourable ecologic conditions. Unlike most previously reported sections, including some sections in South China, the four Frasnian-Famennian (F-F) boundary sections examined here do not show any evidence for black shale. Atrypids are abundant and relatively diverse about 15 to 20 m below the F-F boundary (six species), and very rare about 1-2 m below the boundary (with only two species). It seems that the disappearance of most atrypids occurred well before the F-F boundary. Nine species (including Iowatrypa? qidongensis sp. n.), assigned to six genera, are discussed and described.PaleontologySCI(E)10ARTICLE2345-3604
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Rugose corals and brachiopods across the Frasnian-Famennian boundary in central Hunan, South China
We present taxonomic revision of rugose corals and brachiopods from several Frasnian-Fammenian (F-F) boundary sections in central Hunan Province, China. Diversity of shallow-water rugose corals gradually increased during the Frasnian, but ended with sudden extinction near the end of Frasnian. Ostracods were abundant during the Frasnian; their extinction coincided with anoxic deposition of the end-Frasnian black shale deposits. The early Famennian ostracod fauna is of low diversity. The brachiopod fauna of the late Frasnian (Palmatolepis rhenana and Pa. linguiformis zones) is dominated by atrypids, small-sized cyrtospiriferids, and the rhynchonellid Hunanotoechia. All atrypids disappeared before the F-F boundary with highest rates of extinction below the boundary (probably low in the Pa. linguiformis Zone). The Frasnian cyrtospiriferid fauna is also of low diversity and dominated by small taxa. All but one of the cyrtospiriferid taxa crossed the F-F boundary. The early Famennian post-extinction recovery brachiopod fauna was the result of rapid radiation of new forms shortly after the terminal Frasnian event. The early Famennian fauna is characterized by diverse cyrtospiriferids, abundant Yunnanellina and productoids, Above the early recovery fauna another fauna was recovered, with brachiopods Hunanospirifer and Yunnanella and is correlated with the late or latest Pa. crepida Zone. Sinalosia rugosa gen. et sp. nov. (Productida) is erected.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000176065300014&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701PaleontologySCI(E)14ARTICLE2373-3964
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
- …
