12,629 research outputs found
Correction to: Chamoun et al., Bacterial pathogenesis and interleukin-17: interconnecting mechanisms of immune regulation, host genetics, and microbial virulence that influence severity of infection
No full textChamoun MN, Blumenthal A, Sullivan MJ, Schembri MA, Ulett GC. 2018. Bacterial pathogenesis and interleukin-17: interconnecting mechanisms of immune regulation, host genetics, and microbial virulence that influence severity of infection. Critical Reviews in Microbiology. https://doi.org/10.1080/1040841X.2018.1426556.
When the above article was first published online, the below three corrections were missed.
The author ‘Antje Blumenthal’ was wrongly affiliated to the affiliation “cSchool of Chemistry and Molecular Biosciences, and Australian Infectious Disease Research Centre, The University of Queensland, Brisbane, Australia”. Now this affiliation has been removed for this author.
The affiliation ‘bTranslational Research Institute, The University of Queensland Diamantina Institute, Woolloongabba, Australia’ of the author ‘Antje Blumenthal’ should read ‘bThe University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Australia’.
In Table 3, the sentence ‘Benefit of manipulating IL-17 levels to improve immunization strategies M. tuberculosis’ should read “Benefit of manipulating IL-17 levels to improve immunization strategies against M. tuberculosis”.No Full Tex
Növényvédőszerekre történő vizsgálati módszer kidolgozása GC/MS technikával
No full textDolgozatomban tíz darab ma is használatban lévő növényvédőszerre hozok létre egy érzékeny vizsgálati módszert GC/MS alkalmazásával. Részletezem a módszerfejlesztés menetét és az analitikai rendszer teljesítményjellemzőinek meghatározását, majd összegzem az eredményeket.tbenVegyészmérnökBSc/B
A Model-Based Analysis of GC-Biased Gene Conversion in the Human and Chimpanzee Genomes
Full text linkGC-biased gene conversion (gBGC) is a recombination-associated process that favors the fixation of G/C alleles over A/T alleles. In mammals, gBGC is hypothesized to contribute to variation in GC content, rapidly evolving sequences, and the fixation of deleterious mutations, but its prevalence and general functional consequences remain poorly understood. gBGC is difficult to incorporate into models of molecular evolution and so far has primarily been studied using summary statistics from genomic comparisons. Here, we introduce a new probabilistic model that captures the joint effects of natural selection and gBGC on nucleotide substitution patterns, while allowing for correlations along the genome in these effects. We implemented our model in a computer program, called phastBias, that can accurately detect gBGC tracts about 1 kilobase or longer in simulated sequence alignments. When applied to real primate genome sequences, phastBias predicts gBGC tracts that cover roughly 0.3% of the human and chimpanzee genomes and account for 1.2% of human-chimpanzee nucleotide differences. These tracts fall in clusters, particularly in subtelomeric regions; they are enriched for recombination hotspots and fast-evolving sequences; and they display an ongoing fixation preference for G and C alleles. They are also significantly enriched for disease-associated polymorphisms, suggesting that they contribute to the fixation of deleterious alleles. The gBGC tracts provide a unique window into historical recombination processes along the human and chimpanzee lineages. They supply additional evidence of long-term conservation of megabase-scale recombination rates accompanied by rapid turnover of hotspots. Together, these findings shed new light on the evolutionary, functional, and disease implications of gBGC. The phastBias program and our predicted tracts are freely available. © 2013 Capra et al
GC-FID data of biocatalytic esterification reactions & NMR data of lignin characterization
No full textTabulated chromatographic data (GC-FID) from butyl butyrate esterification reactions. 13C and 31P NMR data from pine kraft lignin (BIOPIVA 100) and cationic pine kraft lignin. A list of sample code identifiers with their descriptions is available upon request from the author.<br
GC-MS fingerprints of 20 batches of Schizonepetae Spica samples and reference chromatogram (R).
No full textGC-MS fingerprints of 20 batches of Schizonepetae Spica samples and reference chromatogram (R).</p
A study on volatile metabolites screening by HS-SPME-GC-MS and HS-GC-IMS for discrimination and characterization of white and yellowed rice
No full textStrappe, P ORCiD: 0000-0003-0100-0558Background and objectives: Yellowed rice results in serious economic losses to grain industry. This study attempted to profile the volatile metabolites in before- and after-yellowing rice of five Chinese common rice cultivars. Application untargeted metabolomics approach to discover the biomarkers in yellowed rice. Findings: The volatile metabolites were detected by headspace-gas chromatography–ion mobility spectrometry (HS-GC-IMS) and headspace solid-phase microextraction–gas chromatography-mass spectrometry (HS-SPME-GC-MS). Yellowed rice emitted more aldehydes, alcohols, furan, and less ester than white rice. Partial least squares-discriminant analysis (PLS-DA) based on GC-MS and GC-IMS data was revealed a good classifying tool for white and yellowed rice. Hexanal, nonanal, octanal, 1-pentanol, and 2-pentyl-furan were selected as the potential markers by the variable importance in projection (VIP) variable selection method. All of these markers were associated with fatty acid oxygenation. Conclusions: Comparative analysis and biomarker identification of the volatile metabolites of different cultivars of Chinese yellowed rice lay a foundation for research on yellowing mechanism. Significance and novelty: The results of the current study provide a useful basis in the rice yellowing mechanism study. Additionally, a rapid rice aroma analysis method using GC-IMS was developed. So in the future, yellowed rapid reorganization GC-IMS technology could be a preferred choice. © 2020 Cereals & Grains Associatio
Mitochondrial phylogeny reveals the artificial introduction of the pale chub Zacco platypus (Cyprinidae) in Taiwan.
No full textAFLPs congruent with morphological differentiation of Asian common minnow Zacco in Taiwan (Pisces: Cyprinidae).
No full text- …
