2,474 research outputs found
Alfonso de' Pazzi (l'Etrusco) (Firenze, 1509-1555)
Scheda relativa ai manoscritti autografi del poeta fiorentino Alfonso de' Pazzi, detto l'Etrusco
Congenital Optic Pit and Argon Laser Photocoagulation
Congenital Optic Pit of the papilla (CPP) is a monolateral little hole located in the inferior temporal portion of the optic nerve
CPP is characterized by a spherical shape involving 1/3 of the optic nerve surface and has a deep face with pigmented base
The most important complication is retinal detachment, in particular macular detachment.
The origin of subretinal fluid is unknown.
We observed 2 cases, both females, 18 and 25 years old, one complicated by macular detachment.
We treated macular detachment with argon laser photocoagulation applying spots around the detached retina and achieved improvement of visual acuity.
Most important diagnostic feature in CPP seems to be retinal angiography, demonstrating hyperfluorescence of CPP and macular detachment
Retinal detachment and convexity intracranial meningioma: an uncommon association.
CASE REPORT: A 70-years-old woman presented with a one week history of progressive loss of vision in the right eye (RE) diagnosed as retinal detachment from 7 to 1 o' clock with retinal break at the 10.30 o' clock associated. Gadolinium enhanced magnetic resonance imaging (MRI) scan of the brain and orbits with fat suppression showed a convexity meningioma. Scleral buckling with a segmental sponge, subretinal fluid drainage and cryopexy were performed with detachment repair. CONCLUSION: In our patient with retinal detachment and convexity meningioma without significant neurological symptoms, performing ocular surgery and close follow up care seemed to be the optimal treatment option
Corneo–conjunctival leukoplakia: histology and confocal microscopy
Purpose: To explore corneo-conjunctival leukoplakias using in vivo confocal microscope and to
compare images to histology and impression cytology specimens.
Methods: Twenty-nine patients affected by corneo-conjunctival leukoplakia, after evaluation with slit lamp exam, were investigated with the Heidelberg Retina Tomograph II, Rostock Cornea Module. Subsequently a diagnostic excision or impression cytology of the cornea and/or conjunctiva was performed.
Results: Histology identified seventeen Pterygia, six Pingueculas, two limbal stem cell deficiency (LSCD), one suture-related corneal vascularization, one cicatricial Pterygoid and two corneal intraepitelial neoplasias (CIN). Confocal microscopy was compared to histopathologic sections and impression citology specimens.
In all patients typical white colour of lesions was attribuable to a different degree of reactive hyperkeratosis.
The main pathological features were visible on our confocal microscopy images: infiltration of conjunctival tissue surrounding lesions, vascularization, cellular morphology and activity, changes in extracellular matrix and modifications of limbar architecture.
Conclusions: Confocal microscopy may be a useful aid for diagnosis and follow up in primitive and secondary corneo-conjunctival lesions. However the ability to provide high resolution, real-time images of the full thickness of the living human cornea and conjunctiva is strictly dependent on surface transparency and additional studies are required to establish exact correlations between confocal microscopy images and histopatology
The chronicle of Alfonson lll and its significance for the historiography of the Asturian kingdom 718-910 AD
The Asturian kingdom provided the earliest organised
resistance in the Iberian peninsula to the Muslim invaders who overthrew the Visigothic state at the start of the 8th century. Information on the origins of the Asturian kingdom is regrettably sparse. Historians of the kingdom are totally reliant on a late 9th-century cycle of Asturian chronicles associated with the royal court, the most substantial of which is the Chronicle of Alfonso III. This work has survived in two fundamental recensions from the 10th century. Historians' gratitude for its existence is tinged with frustration at its readily apparent weaknesses, such as a chronological imprecision on events and an enigmatic brevity in the commentary.
This thesis considers the 9th-century Asturian chronicles in
the context of their own time. In particular, it examines the Chronicle of Alfonso III not as a disappointing source which fails to yield to modern scholars the information they crave on this obscure period of early Spanish history, but, rather, as an expression of the aims of a medieval author and his copyists. The Chronicle was the product of scarce and valuable resources. Its author, within the limits of his literary ability and source of information, transmitted a message which interacted with the individual understanding of its intended audience. This shift of
emphasis in analysing the Chronicle of Alfonso III rests on the assumption that its original text may be recognised in the later recensions which used it, by addition or omission, as a vehicle for their own interests
Use of amniotic membrane transplantation in isolated conjunctival Bowen disease: a case report
PURPOSE: To report a case of isolated conjunctival Bowen disease treated with surgical resection and amniotic membrane transplantation.
METHODS: Interventional case report.
RESULTS: A 70-year-old man was admitted to our clinic with a large conjunctival verrucous plaque well-demarcated in the correspondence of the bulbar conjunctiva in the superior quadrant of the left eye with involved limbal and corneal surface. Ophthalmologic examination on slit-lamp examination and color fundus photographs were carried out before surgery and the results were evaluated.
CONCLUSIONS: Treatment options and treatment studies of Bowen disease are difficult because there are a variety of different protocols and the success of the management depends on several factors (body site, lesion size, number of lesions, and thickness). In the conjunctival localization of the lesion, amniotic membrane transplantation appears to be a useful therapeutic choice after surgical resection of the lesion used to reconstruct ocular and conjunctival surfac
Pterygomaxillary extension of orbital pseudotumor. Case report
Lo pseudotumore orbitario è un’ infiammazione benigna, aspecifica e idiomatica, localizzata nell'orbita e con eccezionale estensione alla base cranica. La sua eziopatogenesi non è conosciuta, definirne la natura istologica è importante per un corretto trattamento.
Riportiamo un raro caso di pseudotumor orbitario con estensione nella fossa infratemporale discutendone gli aspetti clinici e terapeutici
Pseudophakic eye globe disruption
PURPOSE:
Scleral rupture due to bulb bursting can result from a heavy contusion. Owing to refined surgical techniques and the use of antibiotics and cortisone-based medication, more conservative concepts have followed. In major ruptures, the results were almost always very poor, with atrophy or subatrophy of the eyes.
METHODS:
A 63-year-old man with major left ocular trauma and intraocular lens dislocation in the subconjunctival area was referred to the authors for clinical and surgical evaluation.
RESULTS:
Surgery was performed 3 weeks after the trauma to allow for improvement in the patient's condition. The reabsorption of a palpebral-frontal hematoma, which made bulb exploration almost impossible, was fundamental in order to proceed. After 1 year, the best-corrected visual acuity was 0.9. In fact, great improvements in surgical techniques in recent years have allowed us to consider the problem of major rupture in a new way, both technically and from an organizational point of view.
CONCLUSIONS:
In terms of organization, the concept of urgent surgical procedures must be reevaluated, because besides traumatic damage, incomplete surgical measures may result. This makes all treatment useless, in both barely equipped and highly specialized centers
Alfonso Garcia Valdecasas Garcia Valdecasas - vita e opera
La presente tesis doctoral tiene por objetivo analizar la obra y el pensamiento de Alfonso Garcia Valdecasas y Garcia Valdecasas. El estudio se encuadra en el área del derecho romano puesto que él comenzó su carrera como iusromanista, doctorándose en Bolonia como colegial del Real Colegio de España con una tesis dirigida por Emilio Costa. Aquel trabajo recibió el premio Vittorio Emanuele Secondo y, tal y como se demostrará, fue el primer trabajo estrictamente científico de la romanística hispana moderna. Otras publicaciones del autor que se incluyen en el presente trabajo permitirán trazar las líneas del pensamiento jurídico, filosófico y –en parte- político de Alfonso Garcia Valdecasas y Garcia Valdecasas.This PhD thesis aims at analyzing both the work and the thought of Alfonso Garcia-Valdecasas Garcia-Valdecasas. The study is in the field of roman law due to the fact that he started his career as a iusromanist, receiving his PhD in Bologna as a collegiate of the Royal Spanish College with a thesis under the supervision of Professor Emilio Costa. That piece received the Vittorio Emanuele II price and, as it will be demonstrated, it represents the first purely scientific work in the modern hispanic roman law science. Other publications by the author included in this very work will allow to outline the traits of the legal, philosophical and -partly- political thought of Alfonso Garcia-Valdecasas Garcia-Valdecasas.Questa tesi di dottorato ha per obbiettivo analizzare l’opera e il pensiero di Alfonso Garcia-Valdecasas y Garcia-Valdecasas. Lo studio si presenta nell’area del diritto romano poiché egli inizió la sua traiettoria come iusromanista, dottorandosi a Bologna come collegiale del Collegio di Spagna, con una tesi diretta da Emilio Costa. Quel lavoro ricevette il Premio Vittorio Emanuele II e, come si mostrerá, rappresenta il primo lavoro prettamente scientifico della romanistica ispanica moderna. Altre pubblicazioni dell’autore incluse nel presente lavoro permetteranno di delineare i tratti del pensiero giuridico, filosofico e –in parte- político di Alfonso Garcia Valdecasas y Garcia Valdecasas
Neoplastic Implications in Patients Suffering from Hidradenitis Suppurativa under Systemic Treatments
Hidradenitis suppurativa (HS) is a chronic, recurrent, inflammatory skin disease of the apocrine glands. It typically involves the axillary, submammary, genital, inguinal, perineal, and perianal regions. The development of abscesses, sinus tracts, and scars can lead to pain, scarring, disfigurement and decreased quality of life. HS is associated with a wide range of comorbidities. Several studies of co-occurrence of HS and nonmelanoma skin cancer suggest a causal relationship. In an attempt to assess the link between HS and cancer, we performed a systematic review of the current scientific knowledge through a PubMed-based literature search. Results show that HS could be associated with an overall risk of cancer and numerous specific cancers such as: nonmelanoma skin cancer (NMSC), hematologic malignancies, and metastatic cancer. Among NMSC, squamous cell carcinoma (SCC) is considered the most common complication arising in long-standing HS. Based on our review, we suggest that cautious surveillance and active intervention may be warranted in patients with HS. Moreover, an age-appropriate cancer screening should be offered to all patients, especially those who developed HS later in their life or in long-standing moderate to severe HS with multiple comorbidities
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