1,720,961 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Carnosine and anserine as biomarkers of beef meat quality
No full textMeat quality is influenced by pre-slaughter events such as breed, age, environment, stress and post-slaughter events such as carcass pH and temperature, electrical stimulation. All these factors can facilitate the interaction of prooxidants with the cellular macromolecules resulting in the generation of free radicals and the propagation of oxidative reactions. The oxidation is a major deterioration reaction which often results in a significant loss of meat product quality. Carnosine and anserine are naturally occurring skeletal muscle dipeptides. Their function is not completely understood, but they are thought to act both as buffering agents and as antioxidants in vitro e in vivo. The aim of this study was to evaluate the carnosine and anserine content in muscles of conventionally processed young bulls of two different breeds (Charolais and Limousine) raised in 4 different intensive-farms. All young bulls of both races were divided in two categories based on the animal health conditions :“Maximum” and “Minimum” and following the bulls slaughtering muscles were analyzed after 3 and 7 days of storage at 2±0.5°C.
Data indicate that the category “Maximum”, in both breeds, had a higher content of the two peptides compared with the “Minimum” category. The length of the ageing period and the breeding condition (type of breeding, farm, feeding etc) showed little or no influence on carnosine and anserine content
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Characterization of catecholthioether-induced apoptosis in human SH-SY5Y neuroblastoma cells
No full textEvaluation of quercetin cytoxicity on human colon tumor cell line and its possibile role as chemoresistance modulator
No full textAbstract
The development of the resistance to antineoplastic drugs is a major issue in the cancer treatment. Multidrug Resistance (MDR) of cancer cells is often associated with over-expression of P-glycoprotein (P-gp), a plasma membrane transporter. Recently, flavonoids, minor constituents of diet responsible for several biological activities, such as strong antioxidant and antiproliferative properties have been evaluated as MDR modulators with controversial results. Several studies have displayed that polyphenols in certain conditions can act as pro-oxidants, showing cytotoxic and mutagenic effects. We have evaluated the effects of quercetin on tumor cell proliferation and its potential effectiveness as MDR reverser influencing the cytoxicity of antineoplastic drugs (doxorubicin). LoVo wild-type, a human colon adenocarcinoma cell line and LoVo Dx, a multidrug resistant variant cell line, in the presence of quercetin showed a concentration and time-dependent susceptibility to flavonoid toxicity. The cell line WT showed a decrease in viability after 24 hours of quercetin treatment (IC50 = 70M), while the cell line Dx, were less affected (IC50 = 200 M). With respect to the MDR modulating activity, quercetin was found not to be a P-gp inhibitor compared to the well established P-gp reversers, Verapamil and Cyclosprin A. Conversely, quercetin protected both cell lines against doxorubicin toxicity
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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